| HealthInvest Partners AB | 98,000 | $5,826 | 9.28% |
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| SECTOR GAMMA AS | 681,538 | $40,517 | 8.80% |
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| Axiom Investment Management LLC | 58,708 | $3,491 | 7.59% |
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| McCarthy Asset Management, Inc. | 150,449 | $8,944 | 6.23% |
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| Camber Capital Management LP | 2,500,000 | $148,625 | 5.38% |
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| CHIRON CAPITAL MANAGEMENT, LLC | 97,727 | $5,810 | 3.66% |
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| Tekla Capital Management LLC | 1,686,565 | $100,266 | 3.52% |
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| Twin Lakes Capital Management, LLC | 94,099 | $5,594 | 3.16% |
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| MATRIX ASSET ADVISORS INC/NY | 362,989 | $21,580 | 2.90% |
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| PENN DAVIS MCFARLAND INC | 293,030 | $17,421 | 2.80% |
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| Opes Wealth Management LLC | 142,819 | $8,491 | 2.76% |
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| WALLED LAKE PLANNING & WEALTH MANAGEMENT, LLC | 77,043 | $4,580 | 2.72% |
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| CONTINENTAL ADVISORS LLC | 87,937 | $5,228 | 2.58% |
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| Verity & Verity, LLC | 312,641 | $18,587 | 2.58% |
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| TOBAM | 802,991 | $47,738 | 2.40% |
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| MASTERS CAPITAL MANAGEMENT LLC | 1,000,000 | $59,450 | 2.39% |
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| CONTINENTAL ADVISORS LLC | 80,000 | $4,756 | 2.35% |
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| GREYLIN INVESTMENT MANGEMENT INC | 228,570 | $13,588 | 2.33% |
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| BOURGEON CAPITAL MANAGEMENT LLC | 170,124 | $10,114 | 2.29% |
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| MORGAN DEMPSEY CAPITAL MANAGEMENT LLC | 129,434 | $7,695 | 2.28% |
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