| First Light Asset Management, LLC | 1,489,407 | $65,236,027 | 6.20% |
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| Millrace Asset Group, Inc. | 48,730 | $2,134 | 2.64% |
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| SECTORAL ASSET MANAGEMENT INC | 236,532 | $10,360,102 | 2.02% |
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| DAFNA Capital Management LLC | 125,529 | $5,498,170 | 1.71% |
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| NEXT CENTURY GROWTH INVESTORS LLC | 313,724 | $13,741,111 | 1.49% |
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| PERKINS CAPITAL MANAGEMENT INC | 29,350 | $1,286 | 1.28% |
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| Soleus Capital Management, L.P. | 306,000 | $13,402,800 | 1.24% |
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| Hood River Capital Management LLC | 847,342 | $37,113,580 | 1.19% |
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| Tamarack Advisers, LP | 40,000 | $1,752,000 | 1.14% |
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| EMERALD MUTUAL FUND ADVISERS TRUST | 411,400 | $18,019,320 | 1.09% |
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| EMERALD ADVISERS, LLC | 498,972 | $21,854,974 | 1.06% |
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| Granite Investment Partners, LLC | 395,810 | $17,336,478 | 0.73% |
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| Decheng Capital Management III (Cayman), LLC | 46,259 | $2,026,144 | 0.68% |
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| TimesSquare Capital Management, LLC | 904,835 | $39,632 | 0.62% |
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| Bellevue Group AG | 747,560 | $32,743,128 | 0.53% |
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| Champlain Investment Partners, LLC | 1,851,540 | $81,097,452 | 0.53% |
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| Delap Wealth Advisory, LLC | 9,000 | $394,200 | 0.38% |
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| GW&K Investment Management, LLC | 866,527 | $37,954 | 0.38% |
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| ESSEX INVESTMENT MANAGEMENT CO LLC | 52,907 | $2,317,327 | 0.38% |
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| FRED ALGER MANAGEMENT, LLC | 1,435,814 | $62,888,653 | 0.36% |
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