RA Capital Management Q4 2019

RA Capital Management holdings Q4 2019
Name ValueChangeSharesChangeWeightingChange
SYNTHORX INC$679,652
329.56%
9,724,5980.00%20.61%
118.63%
ASCENDIS PHARMA A Ssponsored adr$582,265
46.28%
4,185,342
1.28%
17.66%
-25.55%
RA PHARMACEUTICALS INC$227,998
98.44%
4,858,2600.00%6.91%
0.99%
ARVINAS INC$150,918
320.98%
3,672,872
120.79%
4.58%
114.26%
CHEMOCENTRYX INCNew $126,5363,199,3893.84%
RHYTHM PHARMACEUTICALS INC$124,496
68.49%
5,422,312
58.44%
3.78%
-14.24%
EIDOS THERAPEUTICS INC$124,116
59.55%
2,162,6710.00%3.76%
-18.80%
ZOGENIX INC$117,853
30.20%
2,260,7510.00%3.57%
-33.74%
PHATHOM PHARMACEUTICALS INCNew $113,5623,646,8083.44%
TG THERAPEUTICS INC$109,672
183.88%
9,880,323
43.60%
3.33%
44.48%
SATSUMA PHARMACEUTICALS INC$92,139
31.11%
4,681,8580.00%2.79%
-33.27%
ORCHARD THERAPEUTICS PLCads$87,861
41.56%
6,389,901
22.31%
2.66%
-27.95%
89BIO INCNew $83,1083,161,2142.52%
FORTY SEVEN INCNew $76,1121,933,2502.31%
WAVE LIFE SCIENCES LTD$62,318
-60.96%
7,775,2070.00%1.89%
-80.13%
RETROPHIN INC$60,385
30.66%
4,252,453
6.64%
1.83%
-33.50%
AUDENTES THERAPEUTICS INCNew $53,999902,3831.64%
PREVAIL THERAPEUTICS INC$53,246
28.91%
3,363,6050.00%1.61%
-34.39%
CRINETICS PHARMACEUTICALS INC$47,049
66.82%
1,875,2090.00%1.43%
-15.09%
ARDELYX INCNew $40,2185,358,8631.22%
AXSOME THERAPEUTICS INC$38,017
182.72%
367,816
-44.64%
1.15%
43.89%
IGM BIOSCIENCES INC$37,501
353.02%
982,723
110.72%
1.14%
130.57%
STOKE THERAPEUTICS INC$31,717
31.78%
1,119,9630.00%0.96%
-32.93%
RELMADA THERAPEUTICS INCNew $29,705761,6660.90%
MOMENTA PHARMACEUTICALS INCNew $28,5261,445,8010.87%
SOLID BIOSCIENCES INC$20,342
-56.96%
4,571,1640.00%0.62%
-78.10%
SCPHARMACEUTICALS INC$18,378
-3.58%
3,247,0050.00%0.56%
-50.93%
ALECTOR INC$17,230
19.49%
1,000,0000.00%0.52%
-39.19%
KALA PHARMACEUTICALS INC$16,743
-3.02%
4,537,4780.00%0.51%
-50.64%
GALERA THERAPEUTICS INCNew $13,8731,054,1780.42%
DYNAVAX TECHNOLOGIES CORP$13,533
60.00%
2,365,9120.00%0.41%
-18.57%
PORTOLA PHARMACEUTICALS INC$10,254
-10.96%
429,3990.00%0.31%
-54.68%
ESSA PHARMA INC$5,500
63.20%
1,000,0000.00%0.17%
-16.94%
X4 PHARMACEUTICALS INC$2,892
-52.41%
270,292
-43.47%
0.09%
-75.78%
SENSEONICS HLDGS INCSold $0-2,727,273-0.16%
CHIMERIX INCSold $0-1,782,202-0.25%
ODONATE THERAPEUTICS INCSold $0-200,000-0.31%
MYOVANT SCIENCES LTDSold $0-6,166,875-1.91%
DICERNA PHARMACEUTICALS INCSold $0-2,456,669-2.10%
PRECISION BIOSCIENCES INCSold $0-1,842,366-0.92%
KODIAK SCIENCES INCSold $0-1,025,165-0.88%
Portfolio Information
QuarterQ4 2019
Total value$3,297,714,000
Holdings34
Managers
Peter Kolchinsky
Quarters
2019-12-31
$3,297,714
2019-09-30
$1,678,386
2019-06-30
$1,862,830
2019-03-31
$2,319,025
2018-12-31
$1,717,985
2018-09-30
$1,870,521
2018-06-30
$1,540,247
2018-03-31
$1,305,208
2017-12-31
$1,195,149
2017-09-30
$1,106,912
2017-06-30
$871,430
2017-03-31
$815,257
2016-12-31
$705,844
2016-09-30
$969,369
2016-06-30
$722,235
2016-03-31
$782,348
2015-12-31
$1,010,538
2015-09-30
$696,301
2015-06-30
$994,105
2015-03-31
$1,006,949
2014-12-31
$930,497
2014-09-30
$846,275
2014-06-30
$989,267
2014-03-31
$1,394,409
2013-12-31
$858,468
2013-09-30
$958,088
2013-06-30
$753,991
SEC Filings