RA Capital Management Q4 2018

RA Capital Management holdings Q4 2018
Name ValueChangeSharesChangeWeightingChange
WAVE LIFE SCIENCES LTD$315,807
-15.92%
7,512,0490.00%18.38%
-8.45%
ASCENDIS PHARMA A Ssponsored adr$265,670
-11.59%
4,240,5360.00%15.46%
-3.74%
SYNTHORX INCNew $169,0149,724,5989.84%
ZOGENIX INC$86,854
-6.80%
2,382,168
26.79%
5.06%
1.48%
BIOCRYST PHARMACEUTICALS$86,029
22.09%
10,660,349
15.44%
5.01%
32.93%
ORCHARD THERAPEUTICS PLCadsNew $76,2274,845,9334.44%
INFLARX NV$75,835
12.29%
2,085,089
5.96%
4.41%
22.26%
SOLID BIOSCIENCES INC$72,077
-43.20%
2,689,4440.00%4.20%
-38.15%
MYOVANT SCIENCES LTD$60,907
-33.54%
3,711,549
7.52%
3.55%
-27.64%
EIDOS THERAPEUTICS INC$59,206
174.32%
2,162,6710.00%3.45%
198.67%
CRINETICS PHARMACEUTICALS INC$56,238
15.40%
1,875,209
10.24%
3.27%
25.64%
RHYTHM PHARMACEUTICALS INC$52,425
-7.85%
1,950,3320.00%3.05%
0.33%
IMMUNOMEDICS INC$43,116
-33.65%
3,021,466
-3.15%
2.51%
-27.76%
ARVINAS INC$40,329
-23.83%
3,138,4120.00%2.35%
-17.07%
RA PHARMACEUTICALS INC$33,963
-51.26%
4,858,260
26.13%
1.98%
-46.93%
TG THERAPEUTICS INC$33,613
-26.79%
8,198,3370.00%1.96%
-20.29%
KALVISTA PHARMACEUTICALS INC$28,461
-10.67%
1,441,0700.00%1.66%
-2.74%
MOMENTA PHARMACEUTICALS INC$28,244
-31.09%
2,558,357
64.17%
1.64%
-24.97%
DICERNA PHARMACEUTICALS INC$26,262
-56.25%
2,456,669
-37.54%
1.53%
-52.36%
EIGER BIOPHARMACEUTICALS INCNew $24,5412,415,4581.43%
IOVANCE BIOTHERAPEUTICS INC$24,076
90.88%
2,720,452
142.65%
1.40%
107.83%
MODERNA INCNew $23,1241,514,3261.35%
KALA PHARMACEUTICALS INC$22,188
6.38%
4,537,478
114.72%
1.29%
15.82%
SCPHARMACEUTICALS INC$10,743
-35.94%
2,857,1430.00%0.63%
-30.26%
PROTEON THERAPEUTICS INC$3,036
16.41%
1,337,4620.00%0.18%
26.75%
SAGE THERAPEUTICS INCSold $0-350,933-2.65%
PROGENICS PHARMACEUTICALS INCSold $0-3,030,303-1.02%
APELLIS PHARMACEUTICALS INCSold $0-900,000-0.86%
GLYCOMIMETICS INCSold $0-253,547-0.20%
ENDOCYTE INCSold $0-6,196,143-5.88%
Portfolio Information
QuarterQ4 2018
Total value$1,717,985,000
Holdings25
Managers
Peter Kolchinsky
Quarters
2018-12-31
$1,717,985
2018-09-30
$1,870,521
2018-06-30
$1,540,247
2018-03-31
$1,305,208
2017-12-31
$1,195,149
2017-09-30
$1,106,912
2017-06-30
$871,430
2017-03-31
$815,257
2016-12-31
$705,844
2016-09-30
$969,369
2016-06-30
$722,235
2016-03-31
$782,348
2015-12-31
$1,010,538
2015-09-30
$696,301
2015-06-30
$994,105
2015-03-31
$1,006,949
2014-12-31
$930,497
2014-09-30
$846,275
2014-06-30
$989,267
2014-03-31
$1,394,409
2013-12-31
$858,468
2013-09-30
$958,088
2013-06-30
$753,991
SEC Filings