RA Capital Management Q4 2017

RA Capital Management holdings Q4 2017
Name ValueChangeSharesChangeWeightingChange
WAVE LIFE SCIENCES LTD$263,673
71.02%
7,512,049
5.97%
22.06%
58.39%
ASCENDIS PHARMA A Ssponsored adr$223,562
10.51%
5,580,6900.00%18.71%
2.35%
AVEXIS INC$129,625
8.23%
1,171,278
-5.40%
10.85%
0.24%
SAGE THERAPEUTICS INCNew $74,972455,1736.27%
INFLARX NVNew $60,2542,876,0805.04%
BIOHAVEN PHARMACTL HLDG CO LTD$53,887
-27.82%
1,997,2780.00%4.51%
-33.15%
ZOGENIX INC$45,868
31.88%
1,145,268
15.42%
3.84%
22.15%
DICERNA PHARMACEUTICALS INC$44,839
221.10%
4,965,513
104.46%
3.75%
197.40%
KALA PHARMACEUTICALS INC$39,074
-19.04%
2,113,2360.00%3.27%
-25.02%
MYOVANT SCIENCES LTD$35,777
-18.29%
2,830,4550.00%2.99%
-24.33%
SCPHARMACEUTICALS INCNew $34,5432,857,1432.89%
BIOCRYST PHARMACEUTICALS$34,295
-6.30%
6,984,6920.00%2.87%
-13.22%
KADMON HLDGS INC$22,695
1.62%
6,269,342
-5.96%
1.90%
-5.88%
APELLIS PHARMACEUTICALS INCNew $19,530900,0001.63%
SPERO THERAPEUTICS INCNew $14,4011,225,6471.20%
ENDOCYTE INCNew $14,4013,364,6481.20%
AVEO PHARMACEUTICALS INC$14,125
-65.84%
5,062,759
-55.31%
1.18%
-68.36%
KALVISTA PHARMACEUTICALS INC$14,050
222.99%
1,441,070
143.81%
1.18%
199.14%
RA PHARMACEUTICALS INC$11,490
-41.78%
1,351,8080.00%0.96%
-46.08%
SUNESIS PHARMACEUTICALS INCNew $11,4273,096,8400.96%
CLEMENTIA PHARMACEUTICALS INC COM NPV$11,111
12.38%
585,4030.00%0.93%
4.08%
KRYSTAL BIOTECH INC$7,364
5.52%
700,0000.00%0.62%
-2.27%
ARGENX SEsponsored adrNew $4,78775,8160.40%
G1 THERAPEUTICS INC$3,170
-93.63%
159,780
-94.05%
0.27%
-94.10%
PROTEON THERAPEUTICS INC$2,541
-5.01%
1,337,4620.00%0.21%
-12.02%
CHIASMA INC$2,001
-43.81%
1,176,806
-15.73%
0.17%
-47.96%
ACHILLION PHARMACEUTICALS INC$1,687
-97.24%
585,890
-95.70%
0.14%
-97.45%
VANDA PHARMACEUTICALS INCSold $0-243,971-0.39%
ACORDA THERAPEUTICS INCSold $0-900,259-1.92%
TG THERAPEUTICS INCSold $0-700,000-0.75%
SANGAMO THERAPEUTICS INCSold $0-1,250,000-1.69%
IMMUNOMEDICS INCSold $0-1,478,742-1.87%
INSMED INCSold $0-722,714-2.04%
IGNYTA INCSold $0-4,106,601-4.58%
AQUINOX PHARMACEUTICALS INCSold $0-710,682-0.91%
Portfolio Information
QuarterQ4 2017
Total value$1,195,149,000
Holdings27
Managers
Peter Kolchinsky
Quarters
2017-12-31
$1,195,149
2017-09-30
$1,106,912
2017-06-30
$871,430
2017-03-31
$815,257
2016-12-31
$705,844
2016-09-30
$969,369
2016-06-30
$722,235
2016-03-31
$782,348
2015-12-31
$1,010,538
2015-09-30
$696,301
2015-06-30
$994,105
2015-03-31
$1,006,949
2014-12-31
$930,497
2014-09-30
$846,275
2014-06-30
$989,267
2014-03-31
$1,394,409
2013-12-31
$858,468
2013-09-30
$958,088
2013-06-30
$753,991
SEC Filings