| Tri Locum Partners LP | 6,247,500 | $6,809,775 | 2.18% |
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| Bain Capital Life Sciences Investors, LLC | 15,960,588 | $17,397,041 | 1.94% |
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| Stonepine Capital Management, LLC | 5,273,685 | $5,748,317 | 1.91% |
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| NEA Management Company, LLC | 14,986,793 | $16,335,604 | 1.26% |
|---|
| Sio Capital Management, LLC | 2,599,003 | $2,832,913 | 0.88% |
|---|
| New Leaf Venture Partners, L.L.C. | 335,000 | $365,150 | 0.47% |
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| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,973,683 | $2,151,314 | 0.25% |
|---|
| Monashee Investment Management LLC | 427,265 | $465,719 | 0.20% |
|---|
| Orbimed Advisors | 7,133,515 | $7,775,531 | 0.16% |
|---|
| Parkman Healthcare Partners LLC | 800,000 | $872,000 | 0.16% |
|---|
| Perceptive Advisors | 3,545,454 | $3,864,545 | 0.13% |
|---|
| Polar Capital Holdings Plc | 7,500,000 | $8,175,000 | 0.06% |
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| GSA CAPITAL PARTNERS LLP | 621,587 | $678 | 0.06% |
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| Simplify Asset Management Inc. | 400,000 | $436,000 | 0.05% |
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| UBS OCONNOR LLC | 1,559,986 | $1,700,385 | 0.04% |
|---|
| ARMISTICE CAPITAL, LLC | 2,356,000 | $2,568,040 | 0.04% |
|---|
| 1620 INVESTMENT ADVISORS, INC. | 10,000 | $10,900 | 0.01% |
|---|
| AXA S.A. | 3,147,865 | $3,431,173 | 0.01% |
|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4,276,315 | $4,661,183 | 0.01% |
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| Total Clarity Wealth Management, Inc. | 11,532 | $12,570 | 0.01% |
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