$760 Million is the total value of Ikarian Capital, LLC's 196 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 34.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | Buy | SPDR SER TRcall | $84,092,000 | +712.9% | 935,600 | +912.6% | 11.06% | +617.6% |
| NBIX | New | NEUROCRINE BIOSCIENCES INCcall | $40,277,000 | – | 429,600 | +100.0% | 5.30% | – |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INCcall | $24,192,000 | +173.8% | 313,800 | +213.8% | 3.18% | +141.7% |
| AMGN | New | AMGEN INCcall | $24,182,000 | – | 100,000 | +100.0% | 3.18% | – |
| BIIB | New | BIOGEN INCcall | $23,629,000 | – | 112,200 | +100.0% | 3.11% | – |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INCcall | $22,077,000 | -27.0% | 135,200 | -24.2% | 2.90% | -35.5% |
| RETA | Buy | REATA PHARMACEUTICALS INCput | $21,281,000 | +707.0% | 649,600 | +549.6% | 2.80% | +612.0% |
| BCYC | Sell | BICYCLE THERAPEUTICS PLCsponsored ads | $21,009,000 | -43.7% | 478,784 | -21.9% | 2.76% | -50.3% |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEWput | $20,282,000 | +16.3% | 595,500 | +32.0% | 2.67% | +2.7% |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCput | $19,235,000 | – | 117,800 | +100.0% | 2.53% | – |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $18,323,000 | +13.1% | 537,958 | +28.3% | 2.41% | -0.2% |
| KZR | Buy | KEZAR LIFE SCIENCES INC | $18,001,000 | +5.5% | 1,083,116 | +6.1% | 2.37% | -6.9% |
| UTHR | New | UNITED THERAPEUTICS CORP DELcall | $17,942,000 | – | 100,000 | +100.0% | 2.36% | – |
| HZNP | Sell | HORIZON THERAPEUTICS PUB Lcall | $16,633,000 | -37.5% | 158,100 | -36.0% | 2.19% | -44.8% |
| MIST | Buy | MILESTONE PHARMACEUTICALS IN | $12,383,000 | +8.0% | 1,928,752 | +10.2% | 1.63% | -4.7% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEWcall | $11,718,000 | -48.9% | 344,100 | -42.1% | 1.54% | -54.9% |
| BCYC | New | BICYCLE THERAPEUTICS PLCcall | $11,617,000 | – | 264,700 | +100.0% | 1.53% | – |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $11,585,000 | +42.1% | 110,116 | +45.5% | 1.52% | +25.3% |
| GILD | New | GILEAD SCIENCES INCcall | $10,779,000 | – | 181,300 | +100.0% | 1.42% | – |
| GILD | New | GILEAD SCIENCES INCput | $10,779,000 | – | 181,300 | +100.0% | 1.42% | – |
| ATHA | Sell | ATHIRA PHARMA INCcall | $10,587,000 | -5.5% | 784,200 | -8.8% | 1.39% | -16.6% |
| ACET | Buy | ADICET BIO INC | $10,132,000 | +21.3% | 507,348 | +6.3% | 1.33% | +7.1% |
| ZNTL | Buy | ZENTALIS PHARMACEUTICALS INC | $9,329,000 | -41.9% | 202,203 | +5.8% | 1.23% | -48.7% |
| APLS | Sell | APELLIS PHARMACEUTICALS INCcall | $8,896,000 | -5.9% | 175,100 | -12.4% | 1.17% | -16.9% |
| SAGE | New | SAGE THERAPEUTICS INC | $8,272,000 | – | 249,907 | +100.0% | 1.09% | – |
| SAGE | Buy | SAGE THERAPEUTICS INCcall | $8,275,000 | +4209.9% | 250,000 | +5455.6% | 1.09% | +3651.7% |
| PCVX | Buy | VAXCYTE INC | $7,630,000 | +8.7% | 315,991 | +7.1% | 1.00% | -4.1% |
| TCON | Buy | TRACON PHARMACEUTICALS INC | $7,477,000 | +0.3% | 2,843,232 | +5.7% | 0.98% | -11.4% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $7,320,000 | +30.8% | 239,441 | +33.7% | 0.96% | +15.5% |
| BHVN | New | BIOHAVEN PHARMACTL HLDG CO L | $7,114,000 | – | 60,000 | +100.0% | 0.94% | – |
| SRRA | Sell | SIERRA ONCOLOGY INC | $6,983,000 | -43.5% | 217,915 | -61.7% | 0.92% | -50.2% |
| GOSS | Sell | GOSSAMER BIO INC | $6,730,000 | -49.0% | 775,315 | -33.6% | 0.88% | -55.0% |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $6,524,000 | – | 25,000 | +100.0% | 0.86% | – |
| RIGL | Buy | RIGEL PHARMACEUTICALS INC | $6,390,000 | +449.0% | 2,137,128 | +386.4% | 0.84% | +385.5% |
| KRTX | New | KARUNA THERAPEUTICS INC | $6,340,000 | – | 50,000 | +100.0% | 0.83% | – |
| BLU | Buy | BELLUS HEALTH INC NEW | $6,283,000 | +1462.9% | 913,327 | +1726.7% | 0.83% | +1276.7% |
| IMTX | Buy | IMMATICS N.V | $6,243,000 | -37.0% | 781,388 | +5.9% | 0.82% | -44.4% |
| MCRB | Buy | SERES THERAPEUTICS INC | $5,986,000 | -9.7% | 840,624 | +5.6% | 0.79% | -20.3% |
| SCPH | Buy | SCPHARMACEUTICALS INC | $5,510,000 | +21.8% | 970,098 | +7.6% | 0.72% | +7.6% |
| GLPG | GALAPAGOS NVspon adr | $5,413,000 | +11.4% | 86,865 | 0.0% | 0.71% | -1.7% | |
| New | AMYLYX PHARMACEUTICALS INC | $5,097,000 | – | 396,654 | +100.0% | 0.67% | – | |
| AMGN | New | AMGEN INC | $4,837,000 | – | 20,000 | +100.0% | 0.64% | – |
| RCUS | New | ARCUS BIOSCIENCES INCcall | $4,734,000 | – | 150,000 | +100.0% | 0.62% | – |
| BCYC | New | BICYCLE THERAPEUTICS PLCput | $4,677,000 | – | 106,600 | +100.0% | 0.62% | – |
| KZR | Buy | KEZAR LIFE SCIENCES INCcall | $4,666,000 | +64.9% | 280,800 | +65.9% | 0.61% | +45.5% |
| PFE | New | PFIZER INC | $4,142,000 | – | 80,000 | +100.0% | 0.54% | – |
| BPMC | New | BLUEPRINT MEDICINES CORPcall | $4,088,000 | – | 64,000 | +100.0% | 0.54% | – |
| CMRX | Buy | CHIMERIX INC | $3,852,000 | -24.7% | 841,203 | +5.8% | 0.51% | -33.5% |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $3,856,000 | – | 50,000 | +100.0% | 0.51% | – |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INCcall | $3,806,000 | -12.3% | 160,700 | +26.6% | 0.50% | -22.7% |
| Buy | AADI BIOSCIENCE INC | $3,536,000 | -25.5% | 208,368 | +6.1% | 0.46% | -34.2% | |
| INBX | Buy | INHIBRX INC | $3,516,000 | -46.3% | 157,842 | +5.3% | 0.46% | -52.6% |
| NTLA | New | INTELLIA THERAPEUTICS INC | $3,445,000 | – | 47,408 | +100.0% | 0.45% | – |
| New | AMYLYX PHARMACEUTICALS INCcall | $3,213,000 | – | 250,000 | +100.0% | 0.42% | – | |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $2,846,000 | – | 86,905 | +100.0% | 0.37% | – |
| AYLA | Buy | AYALA PHARMACEUTICALS INC | $2,819,000 | -50.5% | 708,383 | +5.8% | 0.37% | -56.3% |
| ATHA | New | ATHIRA PHARMA INCput | $2,700,000 | – | 200,000 | +100.0% | 0.36% | – |
| STSA | Buy | SATSUMA PHARMACEUTICALS INC | $2,482,000 | -12.3% | 653,448 | +3.8% | 0.33% | -22.7% |
| XFOR | Sell | X4 PHARMACEUTICALS INC | $2,402,000 | -53.7% | 1,372,022 | -39.4% | 0.32% | -59.1% |
| ZLAB | Buy | ZAI LAB LTDcall | $2,336,000 | +287.4% | 53,100 | +453.1% | 0.31% | +241.1% |
| Sell | PARDES BIOSCIENCES INC | $2,338,000 | -64.3% | 323,934 | -19.0% | 0.31% | -68.5% | |
| OVID | Buy | OVID THERAPEUTICS INC | $2,319,000 | +2.4% | 738,372 | +4.7% | 0.30% | -9.5% |
| SVRA | Buy | SAVARA INC | $2,126,000 | +11.3% | 1,622,552 | +5.4% | 0.28% | -1.8% |
| KYMR | New | KYMERA THERAPEUTICS INC | $2,117,000 | – | 50,000 | +100.0% | 0.28% | – |
| WVE | Buy | WAVE LIFE SCIENCES LTD | $2,095,000 | -32.8% | 1,048,039 | +5.5% | 0.28% | -40.9% |
| PMVP | New | PMV PHARMACEUTICALS INCcall | $2,082,000 | – | 100,000 | +100.0% | 0.27% | – |
| PMVP | New | PMV PHARMACEUTICALS INCput | $2,082,000 | – | 100,000 | +100.0% | 0.27% | – |
| CABA | Buy | CABALETTA BIO INC | $2,070,000 | -43.7% | 1,020,070 | +5.1% | 0.27% | -50.4% |
| CNTB | Buy | CONNECT BIOPHARMA HLDGS LTDads | $2,047,000 | +51.6% | 677,859 | +158.5% | 0.27% | +33.8% |
| CLNN | Buy | CLENE INC | $2,026,000 | +1.0% | 514,283 | +5.1% | 0.27% | -11.0% |
| INBX | Buy | INHIBRX INCcall | $1,911,000 | -45.8% | 85,800 | +6.2% | 0.25% | -52.3% |
| GOSS | Buy | GOSSAMER BIO INCcall | $1,836,000 | -18.8% | 211,600 | +5.8% | 0.24% | -28.5% |
| LQDA | Sell | LIQUIDIA CORPORATION | $1,751,000 | +10.6% | 243,904 | -25.1% | 0.23% | -2.5% |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS IN | $1,732,000 | -63.9% | 49,997 | -69.5% | 0.23% | -68.1% |
| LYRA | Buy | LYRA THERAPEUTICS INC | $1,698,000 | -1.2% | 422,338 | +7.0% | 0.22% | -12.9% |
| FNCH | Buy | FINCH THERAPEUTICS GROUP INC | $1,662,000 | -47.2% | 330,523 | +4.7% | 0.22% | -53.3% |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $1,667,000 | – | 375,000 | +100.0% | 0.22% | – |
| VKTX | Buy | VIKING THERAPEUTICS INC | $1,596,000 | -30.7% | 532,429 | +6.3% | 0.21% | -38.8% |
| CLVS | Sell | CLOVIS ONCOLOGY INC | $1,561,000 | -48.2% | 772,339 | -30.6% | 0.20% | -54.3% |
| AUTL | Sell | AUTOLUS THERAPEUTICS PLCspon ads | $1,552,000 | -45.1% | 372,217 | -31.7% | 0.20% | -51.5% |
| TARA | Buy | PROTARA THERAPEUTICS INC | $1,515,000 | -19.6% | 296,426 | +6.1% | 0.20% | -29.2% |
| ALRN | Buy | AILERON THERAPEUTICS INC | $1,487,000 | -4.4% | 2,902,086 | +5.0% | 0.20% | -15.5% |
| Buy | RENOVACOR INC | $1,456,000 | -44.9% | 343,283 | +0.1% | 0.19% | -51.4% | |
| MGNX | Buy | MACROGENICS INC | $1,446,000 | -42.3% | 164,119 | +5.2% | 0.19% | -49.1% |
| ELDN | Buy | ELEDON PHARMACEUTICALS INC | $1,429,000 | -5.9% | 362,537 | +5.2% | 0.19% | -16.8% |
| MRUS | Buy | MERUS N V | $1,420,000 | -12.3% | 53,703 | +5.5% | 0.19% | -22.4% |
| VBLT | Buy | VASCULAR BIOGENICS LTD | $1,404,000 | -9.9% | 830,747 | +5.0% | 0.18% | -20.3% |
| CMMB | Buy | CHEMOMAB THERAPEUTICS LTDsponsored ads | $1,292,000 | -29.4% | 268,104 | +1.1% | 0.17% | -37.5% |
| SYBX | Buy | SYNLOGIC INC | $1,248,000 | +6.6% | 519,775 | +7.4% | 0.16% | -5.7% |
| ACET | Sell | ADICET BIO INCcall | $1,241,000 | -64.5% | 62,100 | -69.0% | 0.16% | -68.7% |
| ANEB | Buy | ANEBULO PHARMACEUTICALS INC | $1,225,000 | +14.4% | 181,199 | +5.2% | 0.16% | +0.6% |
| SNPX | Buy | SYNAPTOGENIX INC | $1,186,000 | -4.3% | 153,226 | +5.2% | 0.16% | -15.7% |
| Buy | BELLICUM PHARMACEUTICALS INC | $1,131,000 | +53.0% | 523,348 | +5.4% | 0.15% | +35.5% | |
| NUVB | Buy | NUVATION BIO INC | $1,122,000 | -34.0% | 213,310 | +6.7% | 0.15% | -41.5% |
| AUPH | Buy | AURINIA PHARMACEUTICALS INC | $1,077,000 | -42.8% | 87,071 | +5.8% | 0.14% | -49.5% |
| PHAT | Buy | PHATHOM PHARMACEUTICALS INC | $1,069,000 | -27.1% | 78,550 | +5.4% | 0.14% | -35.6% |
| CASI | Buy | CASI PHARMACEUTICALS INC | $1,067,000 | +9.1% | 1,320,155 | +7.9% | 0.14% | -4.1% |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $1,047,000 | -2.9% | 316,939 | +2.2% | 0.14% | -14.3% |
| ASND | Buy | ASCENDIS PHARMA A/Ssponsored adr | $1,028,000 | -9.0% | 8,763 | +4.3% | 0.14% | -19.6% |
| BCLI | Buy | BRAINSTORM CELL THERAPEUTICS | $1,022,000 | -11.8% | 304,161 | +5.0% | 0.13% | -22.5% |
| Buy | MAXCYTE INC | $964,000 | -27.2% | 137,958 | +6.1% | 0.13% | -35.5% | |
| VSTM | Buy | VERASTEM INC | $956,000 | -26.9% | 678,023 | +6.4% | 0.13% | -35.4% |
| CABA | Buy | CABALETTA BIO INCcall | $912,000 | -43.1% | 449,000 | +6.1% | 0.12% | -49.8% |
| AKBA | New | AKEBIA THERAPEUTICS INCput | $860,000 | – | 1,200,000 | +100.0% | 0.11% | – |
| CRVS | Buy | CORVUS PHARMACEUTICALS INC | $837,000 | -28.0% | 510,126 | +5.7% | 0.11% | -36.4% |
| ISEE | Buy | IVERIC BIO INC | $825,000 | +6.0% | 49,099 | +5.5% | 0.11% | -6.9% |
| TCDA | New | TRICIDA INCput | $764,000 | – | 92,900 | +100.0% | 0.10% | – |
| BLSA | Buy | BCLS ACQUISITION CORP | $762,000 | +4.7% | 77,274 | +4.7% | 0.10% | -7.4% |
| PBLA | Buy | PANBELA THERAPEUTICS INC | $750,000 | +26.7% | 355,959 | +5.2% | 0.10% | +12.5% |
| HEPA | Buy | HEPION PHARMACEUTICALS INC | $751,000 | +19.2% | 582,137 | +5.2% | 0.10% | +5.3% |
| QSI | Buy | QUANTUM SI INC | $736,000 | -35.2% | 157,363 | +9.0% | 0.10% | -42.6% |
| NKTR | Sell | NEKTAR THERAPEUTICScall | $722,000 | -78.6% | 133,900 | -46.4% | 0.10% | -81.1% |
| IMUX | New | IMMUNIC INCput | $696,000 | – | 61,500 | +100.0% | 0.09% | – |
| NXTC | Buy | NEXTCURE INC | $686,000 | -14.7% | 141,058 | +5.2% | 0.09% | -25.0% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $636,000 | -45.6% | 90,805 | +4.7% | 0.08% | -51.7% |
| IFRX | Buy | INFLARX NV | $639,000 | -59.5% | 349,468 | +5.6% | 0.08% | -64.3% |
| VTGN | Buy | VISTAGEN THERAPEUTICS INC | $633,000 | -31.7% | 511,186 | +7.5% | 0.08% | -39.9% |
| SLDB | SOLID BIOSCIENCES INC | $625,000 | -31.4% | 521,155 | 0.0% | 0.08% | -39.7% | |
| Buy | ASTRIA THERAPEUTICS INC | $619,000 | +30.9% | 92,223 | +5.3% | 0.08% | +15.7% | |
| GMTX | Buy | GEMINI THERAPEUTICS INC | $615,000 | -49.8% | 443,096 | +5.2% | 0.08% | -55.5% |
| Buy | MYMD PHARMACEUTICALS INC | $612,000 | -18.5% | 131,389 | +6.0% | 0.08% | -28.6% | |
| Buy | TENAX THERAPEUTICS INC | $596,000 | -17.5% | 735,097 | +5.9% | 0.08% | -27.8% | |
| HARP | Buy | HARPOON THERAPEUTICS INC | $582,000 | -30.7% | 117,009 | +5.1% | 0.08% | -38.4% |
| KALV | Buy | KALVISTA PHARMACEUTICALS INC | $586,000 | +21.1% | 39,730 | +8.6% | 0.08% | +6.9% |
| CYCN | Buy | CYCLERION THERAPEUTICS INC | $585,000 | -32.4% | 527,462 | +4.9% | 0.08% | -40.3% |
| RLMD | Buy | RELMADA THERAPEUTICS INC | $588,000 | +25.9% | 21,801 | +5.1% | 0.08% | +10.0% |
| AKBA | New | AKEBIA THERAPEUTICS INCcall | $575,000 | – | 800,000 | +100.0% | 0.08% | – |
| ICPT | Buy | INTERCEPT PHARMACEUTICALS IN | $572,000 | +1.8% | 35,149 | +1.7% | 0.08% | -10.7% |
| KOD | New | KODIAK SCIENCES INCput | $565,000 | – | 73,100 | +100.0% | 0.07% | – |
| DMAC | Buy | DIAMEDICA THERAPEUTICS INC | $553,000 | -29.0% | 221,252 | +5.8% | 0.07% | -37.1% |
| Buy | AVALO THERAPEUTICS INC | $554,000 | -54.7% | 764,271 | +6.3% | 0.07% | -59.9% | |
| MBIO | Buy | MUSTANG BIO INC | $551,000 | -34.4% | 546,824 | +8.1% | 0.07% | -42.4% |
| RPHM | Buy | RENEO PHARMACEUTICALS INC | $546,000 | -63.5% | 185,597 | +6.1% | 0.07% | -67.7% |
| VTVT | Buy | VTV THERAPEUTICS INCcl a | $536,000 | -23.1% | 742,980 | +6.1% | 0.07% | -32.7% |
| CRBP | Buy | CORBUS PHARMACEUTICALS HLDGS | $530,000 | -9.2% | 997,627 | +5.2% | 0.07% | -19.5% |
| OTIC | Buy | OTONOMY INC | $525,000 | +21.2% | 218,538 | +4.9% | 0.07% | +6.2% |
| KOD | New | KODIAK SCIENCES INC | $526,000 | – | 68,100 | +100.0% | 0.07% | – |
| RETA | Sell | REATA PHARMACEUTICALS INCcall | $502,000 | -90.5% | 15,300 | -92.4% | 0.07% | -91.6% |
| ASMB | Buy | ASSEMBLY BIOSCIENCES INC | $468,000 | -6.6% | 227,076 | +5.7% | 0.06% | -17.3% |
| BDTX | Buy | BLACK DIAMOND THERAPEUTICS I | $441,000 | -44.9% | 159,390 | +5.9% | 0.06% | -51.3% |
| AGTC | Buy | APPLIED GENETIC TECHNOLOGIES | $440,000 | -40.7% | 412,293 | +5.6% | 0.06% | -47.7% |
| OCUP | Buy | OCUPHIRE PHARMA INC | $401,000 | -9.3% | 124,021 | +5.0% | 0.05% | -19.7% |
| IPA | Buy | IMMUNOPRECISE ANTIBODIES LTD | $399,000 | +1.0% | 77,650 | +5.1% | 0.05% | -11.9% |
| New | NEUROSENSE THERAPEUTICS LTDordinary shares | $397,000 | – | 100,000 | +100.0% | 0.05% | – | |
| VLON | Buy | VALLON PHARMACEUTICALS INC | $380,000 | -67.9% | 201,758 | +1.9% | 0.05% | -71.6% |
| RGLS | Buy | REGULUS THERAPEUTICS INC | $384,000 | -1.0% | 1,289,130 | +4.9% | 0.05% | -13.8% |
| ZLAB | New | ZAI LAB LTDadr | $376,000 | – | 81,843 | +100.0% | 0.05% | – |
| FATE | Buy | FATE THERAPEUTICS INC | $374,000 | -29.2% | 9,640 | +6.7% | 0.05% | -38.0% |
| YMTX | Buy | YUMANITY THERAPEUTICS INC | $355,000 | -47.6% | 236,284 | +3.3% | 0.05% | -53.5% |
| MITO | Buy | STEALTH BIOTHERAPEUTICS CORPsponsored ads | $350,000 | -11.8% | 501,836 | +4.9% | 0.05% | -22.0% |
| Buy | ALTAMIRA THERAPEUTICS LTD | $351,000 | -36.5% | 320,010 | +5.0% | 0.05% | -43.9% | |
| CDAK | Buy | CODIAK BIOSCIENCES INC | $328,000 | -40.8% | 52,177 | +5.0% | 0.04% | -48.2% |
| CYCC | Buy | CYCLACEL PHARMACEUTICALS INC | $319,000 | -17.1% | 104,741 | +5.3% | 0.04% | -26.3% |
| MREO | Buy | MEREO BIOPHARMA GROUP PLCads | $318,000 | +3.6% | 915,856 | +7.3% | 0.04% | -8.7% |
| CBIO | Buy | CATALYST BIOSCIENCES INC | $314,000 | -24.5% | 476,625 | +4.9% | 0.04% | -33.9% |
| ONCT | Buy | ONCTERNAL THERAPEUTICS INC | $292,000 | -35.3% | 210,182 | +5.5% | 0.04% | -43.3% |
| EYPT | Buy | EYEPOINT PHARMACEUTICALS INC | $274,000 | +4.6% | 22,552 | +5.3% | 0.04% | -7.7% |
| AGEN | Buy | AGENUS INC | $267,000 | -19.6% | 108,933 | +5.6% | 0.04% | -28.6% |
| GNCA | Buy | GENOCEA BIOSCIENCES INC | $259,000 | +13.6% | 206,336 | +4.8% | 0.03% | 0.0% |
| BIIB | Sell | BIOGEN INC | $237,000 | -96.7% | 1,122 | -96.2% | 0.03% | -97.1% |
| PASG | Buy | PASSAGE BIO INC | $223,000 | -48.3% | 71,856 | +5.9% | 0.03% | -54.7% |
| TPST | Buy | TEMPEST THERAPEUTICS INC | $210,000 | -32.3% | 61,827 | +5.1% | 0.03% | -39.1% |
| SEEL | Buy | SEELOS THERAPEUTICS INC | $215,000 | -46.0% | 257,883 | +5.6% | 0.03% | -52.5% |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $208,000 | +33.3% | 12,124 | +12.4% | 0.03% | +17.4% |
| LRMR | Buy | LARIMAR THERAPEUTICS INC | $209,000 | -59.0% | 51,606 | +9.4% | 0.03% | -64.5% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $201,000 | -1.5% | 1,237 | +3.5% | 0.03% | -13.3% |
| KOD | Sell | KODIAK SCIENCES INCcall | $199,000 | -98.6% | 25,700 | -84.7% | 0.03% | -98.8% |
| LIFE | Buy | ATYR PHARMA INC | $197,000 | -24.8% | 37,017 | +5.6% | 0.03% | -33.3% |
| ASLN | Buy | ASLAN PHARMACEUTICALS LTDads | $192,000 | +2.7% | 970,747 | +5.8% | 0.02% | -10.7% |
| IVA | Buy | INVENTIVA SAads | $178,000 | -9.6% | 15,579 | +5.6% | 0.02% | -20.7% |
| Buy | BRIGHT MINDS BIOSCIENCES INC | $161,000 | -49.2% | 105,958 | +6.0% | 0.02% | -55.3% | |
| Buy | APTOSE BIOSCIENCES INC | $147,000 | +6.5% | 106,952 | +4.8% | 0.02% | -9.5% | |
| OCUL | Buy | OCULAR THERAPEUTIX INC | $147,000 | -23.0% | 29,644 | +7.6% | 0.02% | -32.1% |
| ENVB | Buy | ENVERIC BIOSCIENCES INC | $141,000 | -62.1% | 423,834 | +6.0% | 0.02% | -65.5% |
| PBYI | PUMA BIOTECHNOLOGY INC | $144,000 | -5.3% | 49,843 | 0.0% | 0.02% | -17.4% | |
| GMDA | Buy | GAMIDA CELL LTD | $135,000 | +70.9% | 32,689 | +5.3% | 0.02% | +50.0% |
| GOSS | New | GOSSAMER BIO INCput | $129,000 | – | 14,900 | +100.0% | 0.02% | – |
| MNMD | Buy | MIND MEDICINE MINDMED INC | $118,000 | -14.5% | 105,958 | +6.0% | 0.02% | -23.8% |
| BTAI | Buy | BIOXCEL THERAPEUTICS INC | $113,000 | +8.7% | 5,428 | +5.1% | 0.02% | 0.0% |
| ORTX | Buy | ORCHARD THERAPEUTICS PLCads | $110,000 | -43.6% | 155,606 | +5.0% | 0.01% | -51.7% |
| NVAX | Buy | NOVAVAX INC | $100,000 | -45.4% | 1,362 | +6.2% | 0.01% | -51.9% |
| CMPX | Buy | COMPASS THERAPEUTICS INC | $100,000 | -55.0% | 74,171 | +6.0% | 0.01% | -60.6% |
| AMYT | Buy | AMRYT PHARMA PLCsponsored ads | $70,000 | -2.8% | 37,248 | +9.1% | 0.01% | -18.2% |
| ATNX | Buy | ATHENEX INC | $68,000 | -34.0% | 80,039 | +5.1% | 0.01% | -40.0% |
| IGMS | Buy | IGM BIOSCIENCES INC | $43,000 | -2.3% | 1,587 | +5.8% | 0.01% | -14.3% |
| Buy | TANGO THERAPEUTICS INC | $42,000 | -25.0% | 5,456 | +5.3% | 0.01% | -25.0% | |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $46,000 | +9.5% | 1,882 | +6.6% | 0.01% | 0.0% |
| ONTX | Buy | ONCONOVA THERAPEUTICS INC | $35,000 | -5.4% | 18,975 | +26.0% | 0.01% | -16.7% |
| SLNO | Buy | SOLENO THERAPEUTICS INC | $29,000 | -42.0% | 128,454 | +5.6% | 0.00% | -42.9% |
| KNTE | KINNATE BIOPHARMA INC | $22,000 | -37.1% | 1,990 | 0.0% | 0.00% | -40.0% | |
| PDSB | Buy | PDS BIOTECHNOLOGY CORP | $22,000 | -21.4% | 3,672 | +5.1% | 0.00% | -25.0% |
| TGTX | Sell | TG THERAPEUTICS INC | $21,000 | -98.9% | 2,292 | -97.7% | 0.00% | -98.9% |
| New | BAUDAX BIO INC | $4,000 | – | 2,966 | +100.0% | 0.00% | – | |
| KPTI | Buy | KARYOPHARM THERAPEUTICS INC | $6,000 | +20.0% | 830 | +5.7% | 0.00% | 0.0% |
| BLUE | Buy | BLUEBIRD BIO INC | $1,000 | -50.0% | 306 | +6.6% | 0.00% | – |
| Buy | 2SEVENTY BIO INC | $1,000 | -50.0% | 99 | +6.5% | 0.00% | – | |
| DCPH | Exit | DECIPHERA PHARMACEUTICALS INput | $0 | – | -800 | -100.0% | -0.00% | – |
| FLACU | Exit | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $0 | – | -941 | -100.0% | -0.00% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS INput | $0 | – | -1,100 | -100.0% | -0.00% | – |
| BXRX | Exit | BAUDAX BIO INC | $0 | – | -95,059 | -100.0% | -0.00% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -1,500 | -100.0% | -0.00% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCput | $0 | – | -1,300 | -100.0% | -0.03% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -2,161 | -100.0% | -0.03% | – |
| DCPH | Exit | DECIPHERA PHARMACEUTICALS INcall | $0 | – | -29,800 | -100.0% | -0.04% | – |
| ALLK | Exit | ALLAKOS INCput | $0 | – | -37,400 | -100.0% | -0.06% | – |
| RFL | Exit | RAFAEL HLDGS INC | $0 | – | -72,515 | -100.0% | -0.06% | – |
| RFL | Exit | RAFAEL HLDGS INCput | $0 | – | -100,000 | -100.0% | -0.08% | – |
| AVIR | Exit | ATEA PHARMACEUTICALS INCcall | $0 | – | -116,600 | -100.0% | -0.16% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INCcall | $0 | – | -100,000 | -100.0% | -0.25% | – |
| ODT | Exit | ODONATE THERAPEUTICS INC | $0 | – | -1,340,631 | -100.0% | -0.27% | – |
| TGTX | Exit | TG THERAPEUTICS INCput | $0 | – | -98,600 | -100.0% | -0.28% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -164,174 | -100.0% | -0.28% | – |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -23,700 | -100.0% | -0.30% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INCcall | $0 | – | -22,300 | -100.0% | -0.31% | – |
| ALLK | Exit | ALLAKOS INCcall | $0 | – | -218,000 | -100.0% | -0.32% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -172,521 | -100.0% | -0.49% | – |
| IBB | Exit | ISHARES TRishares biotech | $0 | – | -24,022 | -100.0% | -0.55% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INCput | $0 | – | -196,000 | -100.0% | -0.56% | – |
| RCUS | Exit | ARCUS BIOSCIENCES INCput | $0 | – | -124,600 | -100.0% | -0.75% | – |
| ZGNX | Exit | ZOGENIX INCcall | $0 | – | -590,400 | -100.0% | -1.43% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INCput | $0 | – | -909,700 | -100.0% | -2.26% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INCcall | $0 | – | -399,400 | -100.0% | -5.36% | – |
| XBI | Exit | SPDR SER TRput | $0 | – | -542,400 | -100.0% | -9.05% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-13
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| XENON PHARMACEUTICALS INC | 15 | Q2 2023 | 1.5% |
| OCULAR THERAPEUTIX INC | 15 | Q3 2023 | 1.4% |
| SAREPTA THERAPEUTICS INC | 14 | Q3 2023 | 6.4% |
| X4 PHARMACEUTICALS INC - PIPE | 14 | Q2 2023 | 1.4% |
| PROTARA THERAPEUTICS INC | 14 | Q3 2023 | 1.2% |
| SPDR SER TR | 13 | Q3 2023 | 9.0% |
| VAXCYTE INC | 13 | Q3 2023 | 2.9% |
| TRACON PHARMACEUTICALS INC | 13 | Q3 2023 | 1.4% |
| MILESTONE PHARMACEUTICALS IN | 13 | Q3 2023 | 1.7% |
| BELLUS HEALTH INC NEW | 13 | Q1 2023 | 1.8% |
View Ikarian Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Milestone Pharmaceuticals Inc. | February 14, 2023 | 460,416 | 1.3% |
| X4 Pharmaceuticals, Inc | February 14, 2023 | 349,133 | 0.3% |
| aTYR PHARMA INC | February 14, 2022 | 35,048 | 0.1% |
| Cyclacel Pharmaceuticals, Inc. | February 14, 2022 | 99,422 | 1.0% |
| KalVista Pharmaceuticals, Inc. | February 14, 2022 | 36,576 | 0.2% |
| Lyra Therapeutics, Inc. | February 14, 2022 | 394,536 | 3.0% |
| Odonate Therapeutics, Inc. | February 14, 2022 | 1,340,631 | 3.5% |
| Protara Therapeutics, Inc. | February 14, 2022 | 279,256 | 2.5% |
| Science 37 Holdings, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
| scPharmaceuticals Inc. | February 14, 2022 | 901,362 | 3.3% |
View Ikarian Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-05 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
View Ikarian Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.