Name,Ticker,Title of class,Class,Change,CUSIP,Value,Shares or principal amount,Weighting Tesla Inc,TSLA,,Sell,88160R101,302029000.0,721988.0,7.618 Illumina Inc,ILMN,,Buy,452327109,241420000.0,727740.0,6.089 Square Inc,SQ,,Buy,852234103,234474000.0,3747978.0,5.914 CRISPR Therapeutics AG,CRSP,,Buy,H17182108,180074000.0,2956635.0,4.542 Stratasys Ltd,SSYS,,Buy,M85548101,171183000.0,8463934.0,4.318 Invitae Corp,NVTA,,Buy,46185L103,169512000.0,10509132.0,4.275 Editas Medicine Inc,EDIT,,Sell,28106W103,131684000.0,4447277.0,3.321 Intellia Therapeutics Inc,NTLA,,Buy,45826J105,128237000.0,8741432.0,3.234 2U Inc,TWOU,,Buy,90214J101,125234000.0,5220253.0,3.159 Zillow Group Inc,ZG,,New,98954M101,110098000.0,2407049.0,2.777 Xilinx Inc,XLNX,,Buy,983919101,104276000.0,1066539.0,2.63 Roku Inc,ROKU,,Buy,77543R102,98762000.0,737580.0,2.491 Splunk Inc,SPLK,,Sell,848637104,94739000.0,632564.0,2.389 Twitter Inc,TWTR,,Buy,90184L102,94480000.0,2947892.0,2.383 LendingTree Inc,TREE,,Buy,52603B107,86374000.0,284649.0,2.179 NanoString Technologies Inc,NSTG,,Sell,63009R109,84999000.0,3055316.0,2.144 Proto Labs Inc,PRLB,,Buy,743713109,81740000.0,804925.0,2.062 Veracyte Inc,VCYT,,Buy,92337F107,77853000.0,2788436.0,1.964 salesforce.com Inc,CRM,,Buy,79466L302,76529000.0,470544.0,1.93 Trade Desk Inc/The,TTD,,Buy,88339J105,70424000.0,271092.0,1.776 Teladoc Health Inc,TDOC,,Sell,87918A105,62845000.0,750655.0,1.585 MercadoLibre Inc,MELI,,Buy,58733R102,58584000.0,102431.0,1.478 Tencent Holdings Ltd,TCEHY,adr,Sell,88032Q109,56419000.0,1175156.0,1.423 NVIDIA Corp,NVDA,,Sell,67066G104,55233000.0,234736.0,1.393 Netflix Inc,NFLX,,Buy,64110L106,53826000.0,166350.0,1.358 LendingClub Corp,LC,,Buy,52603A208,53738000.0,4258140.0,1.355 Compugen Ltd,CGEN,,Buy,M25722105,53493000.0,8975310.0,1.349 Materialise NV,MTLS,adr,Buy,57667T100,51898000.0,2834406.0,1.309 Teradyne Inc,TER,,Sell,880770102,44665000.0,655002.0,1.127 Cerus Corp,CERS,,Buy,157085101,39737000.0,9416460.0,1.002 Autodesk Inc,ADSK,,Buy,052769106,37673000.0,205347.0,0.95 Eventbrite Inc,EB,,Buy,29975E109,37638000.0,1866050.0,0.949 Syros Pharmaceuticals Inc,SYRS,,Buy,87184Q107,35088000.0,5077807.0,0.885 Alibaba Group Holding Ltd,BABA,adr,Buy,01609W102,32259000.0,152094.0,0.814 Pinterest Inc,PINS,,Buy,72352L106,30892000.0,1657274.0,0.779 Seres Therapeutics Inc,MCRB,,Buy,81750R102,25095000.0,7273840.0,0.633 Cellectis SA,CLLS,adr,Buy,15117K103,22975000.0,1342001.0,0.579 Iovance Biotherapeutics Inc,IOVA,,Buy,462260100,22790000.0,823344.0,0.575 Apple Inc,AAPL,,Sell,037833100,21030000.0,71615.0,0.53 Amazon.com Inc,AMZN,,Buy,023135106,20796000.0,11254.0,0.525 Grayscale Bitcoin Trust BTC,,open-end fund,Buy,389637109,19241000.0,2349322.0,0.485 ExOne Co/The,XONE,,Buy,302104104,17686000.0,2370763.0,0.446 Cloudera Inc,CLDR,,Sell,18914U100,16144000.0,1388111.0,0.407 Inovio Pharmaceuticals Inc,INO,,Buy,45773H201,15130000.0,4584966.0,0.382 Arcturus Therapeutics Holdings,ARCT,,Buy,03969T109,15041000.0,1383756.0,0.379 Twilio Inc,TWLO,,Buy,90138F102,14661000.0,149177.0,0.37 Pinduoduo Inc,PDD,adr,Sell,722304102,13495000.0,356811.0,0.34 Ionis Pharmaceuticals Inc,IONS,,Buy,462222100,13050000.0,216025.0,0.329 Baidu Inc,BIDU,adr,Sell,056752108,12878000.0,101885.0,0.325 CareDx Inc,CDNA,,Buy,14167L103,12196000.0,565438.0,0.308 Guardant Health Inc,GH,,Buy,40131M109,11862000.0,151807.0,0.299 Incyte Corp,INCY,,Buy,45337C102,11778000.0,134882.0,0.297 AeroVironment Inc,AVAV,,Buy,008073108,11288000.0,182832.0,0.285 Codexis Inc,CDXS,,Buy,192005106,10935000.0,683855.0,0.276 PayPal Holdings Inc,PYPL,,Buy,70450Y103,10155000.0,93880.0,0.256 Shopify Inc,SHOP,,Buy,82509L107,9766000.0,24563.0,0.246 HubSpot Inc,HUBS,,Buy,443573100,9443000.0,59580.0,0.238 Spotify Technology SA,SPOT,,Buy,L8681T102,8918000.0,59630.0,0.225 Advanced Micro Devices Inc,AMD,,Sell,007903107,8715000.0,190039.0,0.22 Fate Therapeutics Inc,FATE,,Buy,31189P102,8437000.0,431128.0,0.213 Aptiv PLC,APTV,,Sell,G6095L109,8347000.0,87890.0,0.211 Twist Bioscience Corp,TWST,,Buy,90184D100,8371000.0,398613.0,0.211 Snap Inc,SNAP,,Buy,83304A106,8221000.0,503430.0,0.207 Adobe Inc,ADBE,,Buy,00724F101,7911000.0,23986.0,0.2 Pacific Biosciences of Califor,PACB,,Buy,69404D108,7758000.0,1509414.0,0.196 Castle Biosciences Inc,CSTL,,Buy,14843C105,7081000.0,206014.0,0.179 Organovo Holdings Inc,ONVO,,Buy,68620A104,6936000.0,19499439.0,0.175 Personalis Inc,PSNL,,Buy,71535D106,6822000.0,625856.0,0.172 Cellular Biomedicine Group Inc,CBMG,,Buy,15117P102,6689000.0,411880.0,0.169 Rubius Therapeutics Inc,RUBY,,Sell,78116T103,6467000.0,680764.0,0.163 Workday Inc,WDAY,,Buy,98138H101,6154000.0,37421.0,0.155 Zscaler Inc,ZS,,Buy,98980G102,5875000.0,126339.0,0.148 Alteryx Inc,AYX,,New,02156B103,5744000.0,57396.0,0.145 Atlassian Corp PLC,TEAM,,Buy,G06242104,5344000.0,44410.0,0.135 Trimble Inc,TRMB,,Buy,896239100,5339000.0,128075.0,0.135 JD.com Inc,JD,adr,Sell,47215P106,5199000.0,147581.0,0.131 ANSYS Inc,ANSS,,Sell,03662Q105,3586000.0,13930.0,0.09 NXP Semiconductors NV,NXPI,,Buy,N6596X109,3497000.0,27476.0,0.088 Taiwan Semiconductor Manufactu,TSM,adr,Sell,874039100,3476000.0,59833.0,0.088 Iridium Communications Inc,IRDM,,Buy,46269C102,3425000.0,138992.0,0.086 Bristol-Myers Squibb Co,BMY,,Sell,110122108,3406000.0,53054.0,0.086 Alphabet Inc,GOOGL,,New,02079K305,2760000.0,2061.0,0.07 Sea Ltd,SE,adr,New,81141R100,2702000.0,67191.0,0.068 Rakuten Inc,RKUNY,adr,Buy,75102W108,2629000.0,309129.0,0.066 Cognex Corp,CGNX,,Sell,192422103,2614000.0,46649.0,0.066 Meituan Dianping,,,Sell,G59669104,2564000.0,196027.0,0.065 Kratos Defense & Security Solu,KTOS,,Buy,50077B207,2590000.0,143836.0,0.065 Elbit Systems Ltd,ESLT,,Sell,M3760D101,2542000.0,16394.0,0.064 Intercontinental Exchange Inc,ICE,,Buy,45866F104,2554000.0,27593.0,0.064 SLM Solutions Group AG,,,Sell,D6T690109,2479000.0,125343.0,0.063 Komatsu Ltd,KMTUY,adr,Buy,500458401,2480000.0,103154.0,0.063 HP Inc,HPQ,,Buy,40434L105,2443000.0,118859.0,0.062 FLIR Systems Inc,FLIR,,Buy,302445101,2408000.0,46253.0,0.061 SBI Holdings Inc/Japan,,,Buy,J6991H100,2432000.0,114400.0,0.061 Renishaw PLC,,,Buy,G75006117,2397000.0,47956.0,0.06 Rakuten Inc,,,Buy,J64264104,2292000.0,266905.0,0.058 Pluristem Therapeutics Inc,PSTI,,Buy,72940R300,2308000.0,585694.0,0.058 Straumann Holding AG,,,Sell,H8300N119,2249000.0,2291.0,0.057 MGI Digital Graphic Technology,,,Sell,F4090S113,2277000.0,37140.0,0.057 Intuitive Surgical Inc,ISRG,,Sell,46120E602,2155000.0,3646.0,0.054 3D Systems Corp,DDD,,Sell,88554D205,2118000.0,242026.0,0.053 HDFC Bank Ltd,HDB,adr,Buy,40415F101,2059000.0,32498.0,0.052 Adyen NV,,,Buy,N3501V104,1901000.0,2316.0,0.048 Deere & Co,DE,,Buy,244199105,1885000.0,10880.0,0.048 ZhongAn Online P&C Insurance C,,,Buy,Y989DF109,1846000.0,511700.0,0.047 Intuit Inc,INTU,,Sell,461202103,1843000.0,7037.0,0.046 Guidewire Software Inc,GWRE,,Sell,40171V100,1825000.0,16630.0,0.046 Intrexon Corp,XON,,Buy,46122T102,1780000.0,324891.0,0.045 General Motors Co,GM,,Sell,37045V100,1517000.0,41437.0,0.038 Z Holdings Corp,,,New,J9894K105,1292000.0,305100.0,0.033 TransUnion,TRU,,Sell,89400J107,1141000.0,13325.0,0.029 PTC Inc,PTC,,Buy,69370C100,1136000.0,15174.0,0.029 Microsoft Corp,MSFT,,Sell,594918104,1107000.0,7019.0,0.028 Wirecard AG,,,Buy,D22359133,1120000.0,9291.0,0.028 Dassault Systemes SE,,,Sell,F2457H472,1053000.0,6401.0,0.027 Verisk Analytics Inc,VRSK,,Buy,92345Y106,1040000.0,6964.0,0.026 Charles Schwab Corp/The,SCHW,,Buy,808513105,1037000.0,21800.0,0.026 Facebook Inc,FB,,Sell,30303M102,1028000.0,5010.0,0.026 Altair Engineering Inc,ALTR,,Sell,021369103,997000.0,27758.0,0.025 DocuSign Inc,DOCU,,Buy,256163106,947000.0,12772.0,0.024 Discovery Ltd,,,New,S2192Y109,906000.0,104920.0,0.023 AquaBounty Technologies Inc,AQB,,Buy,03842K200,882000.0,406682.0,0.022 Interactive Brokers Group Inc,IBKR,,Sell,45841N107,831000.0,17821.0,0.021 Cornerstone OnDemand Inc,CSOD,,New,21925Y103,834000.0,14243.0,0.021 Nasdaq Inc,NDAQ,,Sell,631103108,800000.0,7474.0,0.02 Conformis Inc,CFMS,,Buy,20717E101,638000.0,425240.0,0.016 Inmode Ltd,INMD,,New,M5425M103,540000.0,13786.0,0.014 Bellicum Pharmaceuticals Inc,BLCM,,Buy,079481107,538000.0,417433.0,0.014 Galmed Pharmaceuticals Ltd,GLMD,,Buy,M47238106,525000.0,90748.0,0.013 AudioCodes Ltd,AUDC,,Sell,M15342104,496000.0,19300.0,0.013 UroGen Pharma Ltd,URGN,,Buy,M96088105,535000.0,16025.0,0.013 Align Technology Inc,ALGN,,Buy,016255101,533000.0,1911.0,0.013 Kamada Ltd,KMDA,,Sell,M6240T109,478000.0,69617.0,0.012 AMETEK Inc,AME,,Sell,031100100,461000.0,4621.0,0.012 Hexagon AB,,,Sell,W40063104,486000.0,8634.0,0.012 Malam - Team Ltd,,,New,M87437105,417000.0,2199.0,0.011 Teva Pharmaceutical Industries,TEVA,adr,Sell,881624209,452000.0,46129.0,0.011 FARO Technologies Inc,FARO,,Sell,311642102,435000.0,8640.0,0.011 Bezeq The Israeli Telecommunic,,,Sell,M2012Q100,437000.0,544272.0,0.011 Ultra Clean Holdings Inc,UCTT,,Sell,90385V107,446000.0,18986.0,0.011 Perion Network Ltd,,,New,M78673114,426000.0,68451.0,0.011 Danel Adir Yeoshua Ltd,,,Sell,M27013107,442000.0,4754.0,0.011 Cellcom Israel Ltd,CELJF,,Sell,M2196U109,430000.0,135055.0,0.011 Fiverr International Ltd,FVRR,,Sell,M4R82T106,391000.0,16635.0,0.01 Mellanox Technologies Ltd,MLNX,,Sell,M51363113,377000.0,3214.0,0.01 Fattal Holdings 1998 Ltd,,,Sell,M4148G105,382000.0,2345.0,0.01 Zip Co Ltd,,,New,Q9899L134,390000.0,156718.0,0.01 One Software Technologies Ltd,,,Sell,M9866H102,404000.0,5288.0,0.01 Taro Pharmaceutical Industries,TARO,,Sell,M8737E108,414000.0,4707.0,0.01 Matrix IT Ltd,,,Sell,M6859E153,414000.0,20581.0,0.01 Allot Ltd,ALLT,,Sell,M0854Q105,399000.0,46919.0,0.01 CyberArk Software Ltd,CYBR,,Buy,M2682V108,408000.0,3499.0,0.01 Camtek Ltd/Israel,CAMT,,Sell,M20791105,382000.0,35243.0,0.01 Nova Measuring Instruments Ltd,NVMI,,Sell,M7516K103,412000.0,10879.0,0.01 Tower Semiconductor Ltd,TSEM,,Sell,M87915274,386000.0,16035.0,0.01 Radware Ltd,RDWR,,Sell,M81873107,396000.0,15376.0,0.01 Sapiens International Corp NV,SPNS,,Sell,G7T16G103,415000.0,18064.0,0.01 SolarEdge Technologies Inc,SEDG,,Sell,83417M104,404000.0,4251.0,0.01 Bertrandt AG,,,Buy,D1014N107,399000.0,6323.0,0.01 Magic Software Enterprises Ltd,MGIC,,New,559166103,381000.0,39134.0,0.01 Siemens AG,,,Sell,D69671218,361000.0,2764.0,0.009 NuVasive Inc,NUVA,,Sell,670704105,360000.0,4660.0,0.009 Nice Ltd,NICE,adr,Sell,653656108,370000.0,2382.0,0.009 Redhill Biopharma Ltd,RDHL,adr,Buy,757468103,354000.0,58373.0,0.009 Meituan Dianping,MPNGY,adr,New,58533E103,372000.0,14389.0,0.009 Kaiser Aluminum Corp,KALU,,Sell,483007704,341000.0,3079.0,0.009 General Electric Co,GE,,Sell,369604103,372000.0,33337.0,0.009 OC Oerlikon Corp AG,,,Sell,H59187106,351000.0,29881.0,0.009 BATM Advanced Communications,,,New,M19199112,347000.0,696776.0,0.009 Bet Shemesh Engines Holdings 1,,,Sell,M20119109,363000.0,9254.0,0.009 Check Point Software Technolog,CHKP,,Sell,M22465104,367000.0,3303.0,0.009 Evogene Ltd,EVGN,,Buy,M4119S104,345000.0,227211.0,0.009 FMS Enterprises Migun Ltd,,,Sell,M42619102,355000.0,9571.0,0.009 Foamix Pharmaceuticals Ltd,FOMX,,Sell,M46135105,367000.0,110343.0,0.009 Gilat Satellite Networks Ltd,GILT,,Sell,M51474118,344000.0,43487.0,0.009 Hilan Ltd,,,Sell,M5299H123,346000.0,8605.0,0.009 Ituran Location and Control Lt,ITRN,,Sell,M6158M104,364000.0,14474.0,0.009 Partner Communications Co Ltd,,,Sell,M78465107,354000.0,79452.0,0.009 Silicom Ltd,SILC,,Sell,M84116108,368000.0,11057.0,0.009 Wix.com Ltd,WIX,,Sell,M98068105,353000.0,2884.0,0.009 Moog Inc,MOGA,,Sell,615394202,304000.0,3560.0,0.008 United Parcel Service Inc,UPS,,Sell,911312106,301000.0,2568.0,0.008 Medtronic PLC,MDT,,Sell,G5960L103,318000.0,2802.0,0.008 Lincoln Electric Holdings Inc,LECO,,Sell,533900106,335000.0,3462.0,0.008 Intercure Ltd,,,Buy,M549GJ103,311000.0,288825.0,0.008 Arconic Inc,L100PS,,Sell,03965L100,337000.0,10954.0,0.008 Enlivex Therapeutics Ltd,ENLV,,New,M4130Y106,323000.0,38536.0,0.008 Stryker Corp,SYK,,Sell,863667101,296000.0,1411.0,0.007 Ceragon Networks Ltd,CRNT,,Sell,M22013102,273000.0,129788.0,0.007 Aerojet Rocketdyne Holdings In,AJRD,,Sell,007800105,288000.0,6308.0,0.007 Silvergate Capital Corp,SI,,New,82837P408,246000.0,15471.0,0.006 Z Holdings Corp,YAHOY,adr,New,98877X101,210000.0,24935.0,0.005 Nano Dimension Ltd,NNDM,adr,Sell,63008G203,184000.0,72612.0,0.005 Wirecard AG,,adr,Sell,97654L108,201000.0,3360.0,0.005 FirstRand Ltd,,,Sell,S5202Z131,149000.0,34982.0,0.004 Eastman Kodak Co,KODK,,Sell,277461406,79000.0,17072.0,0.002 LINE Corp,LN,adr,Sell,53567X101,64000.0,1314.0,0.002 Nintendo Co Ltd,,, ,J51699106,69000.0,171.0,0.002 Arkema SA,,,Sell,F0392W125,43000.0,409.0,0.001 Allegheny Technologies Inc,ATI,,Buy,01741R102,41000.0,1995.0,0.001 SGL Carbon SE,,,Buy,D6949M108,43000.0,8041.0,0.001 Henkel AG & Co KGaA,,preference,Sell,D3207M110,41000.0,392.0,0.001 Evonik Industries AG,,,Sell,D2R90Y117,48000.0,1571.0,0.001 Bayer AG,,, ,D0712D163,32000.0,390.0,0.001 Xerox Holdings Corp,XRX,,Buy,98421M106,51000.0,1384.0,0.001 DuPont de Nemours Inc,DD,,Sell,26614N102,40000.0,617.0,0.001 Eastman Chemical Co,EMN,,Sell,277432100,45000.0,563.0,0.001 3M Co,MMM,,Sell,88579Y101,45000.0,253.0,0.001 Hexcel Corp,HXL,,Sell,428291108,39000.0,534.0,0.001 Koninklijke DSM NV,,,Sell,N5017D122,44000.0,338.0,0.001 Regeneron Pharmaceuticals Inc,REGN,,Sell,75886F107,33000.0,89.0,0.001 PolyOne Corp,POL,,Sell,73179P106,47000.0,1288.0,0.001 Sandvik AB,,,Sell,W74857165,49000.0,2505.0,0.001 Toray Industries Inc,,,Sell,J89494116,37000.0,5508.0,0.001 SoftBank Group Corp,,, ,J75963108,48000.0,1110.0,0.001 GMO internet Inc,,,New,J1822R104,51000.0,2700.0,0.001 FANUC Corp,,, ,J13440102,41000.0,220.0,0.001 Carpenter Technology Corp,CRS,,Sell,144285103,39000.0,785.0,0.001 Fidelity Government Cash Reser,,open-end fund,Exit,316067107,0.0,-3675.0,0.0 Fidelity Money Market Fund,,fund of funds,Exit,31617H805,0.0,-204.0,0.0 Fidelity Government Portfolio,,open-end fund,Exit,31607A703,0.0,0.0,0.0 Medidata Solutions Inc,MDSO,,Exit,58471A105,0.0,-211.0,0.0 Fidelity Municipal Money Marke,,open-end fund,Exit,316048107,0.0,-1544.0,0.0 5N Plus Inc,,,Exit,33833X101,0.0,-23087.0,-0.001 Visa Inc,V,,Exit,92826C839,0.0,-223.0,-0.001 SoftBank Group Corp,SFTBY,adr,Exit,83404D109,0.0,-1988.0,-0.001 GMO internet Inc,,,Exit,J1727L103,0.0,-2700.0,-0.001 MSCI Inc,MSCI,,Exit,55354G100,0.0,-145.0,-0.001 Intec Pharma Ltd,,,Exit,M53644106,0.0,-144414.0,-0.002 ASX Ltd,,,Exit,Q0604U105,0.0,-1579.0,-0.002 Xero Ltd,,,Exit,Q98665104,0.0,-3465.0,-0.003 Thermo Fisher Scientific Inc,TMO,,Exit,883556102,0.0,-897.0,-0.006 MediWound Ltd,MDWD,,Exit,M68830104,0.0,-130468.0,-0.009 Brainsway Ltd,,,Exit,M2043H103,0.0,-90614.0,-0.01 Fidelity Government Money Mark,,open-end fund,Exit,31617H102,0.0,-1037841.0,-0.023 Alphabet Inc,GOOG,,Exit,02079K107,0.0,-1479.0,-0.039 Titomic Ltd,,,Exit,Q90630114,0.0,-1471255.0,-0.048 LINE Corp,,,Exit,J38932109,0.0,-80154.0,-0.049 Bluebird Bio Inc,BLUE,,Exit,09609G100,0.0,-40200.0,-0.081 Nutanix Inc,NTNX,,Exit,67059N108,0.0,-209512.0,-0.12 GrubHub Inc,GRUB,,Exit,400110102,0.0,-121224.0,-0.149 Zillow Group Inc,Z,,Exit,98954M200,0.0,-2336106.0,-1.521