$304 Million is the total value of Ghost Tree Capital, LLC's 70 reported holdings in Q3 2023. The portfolio turnover from Q2 2023 to Q3 2023 was 73.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | SPDR SER TRcall | $21,906,000 | -12.2% | 300,000 | 0.0% | 7.20% | -12.6% | |
| MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $18,810,000 | +11.8% | 330,000 | 0.0% | 6.19% | +11.3% | ||
| SRPT | New | SAREPTA THERAPEUTICS INCcall | $18,183,000 | – | 150,000 | +100.0% | 5.98% | – |
| New | MOONLAKE IMMUNOTHERAPEUTICSput | $14,250,000 | – | 250,000 | +100.0% | 4.69% | – | |
| AKRO | New | AKERO THERAPEUTICS INCcall | $12,645,000 | – | 250,000 | +100.0% | 4.16% | – |
| KRYS | Buy | KRYSTAL BIOTECH INC | $9,280,000 | +295.2% | 80,000 | +300.0% | 3.05% | +293.8% |
| MDGL | Buy | MADRIGAL PHARMACEUTICALS INC | $8,397,300 | -33.9% | 57,500 | +4.5% | 2.76% | -34.1% |
| TGTX | Buy | TG THERAPEUTICS INC | $8,360,000 | -59.2% | 1,000,000 | +21.2% | 2.75% | -59.4% |
| ASND | Sell | ASCENDIS PHARMA A/Ssponsored adr | $7,959,400 | -10.8% | 85,000 | -15.0% | 2.62% | -11.1% |
| AXSM | AXSOME THERAPEUTICS INC | $7,687,900 | -2.7% | 110,000 | 0.0% | 2.53% | -3.1% | |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $7,604,311 | +112.9% | 664,132 | +91.2% | 2.50% | +112.1% |
| PCVX | Sell | VAXCYTE INC | $7,137,200 | -49.0% | 140,000 | -50.0% | 2.35% | -49.2% |
| TARS | Buy | TARSUS PHARMACEUTICALS INC | $7,108,000 | +162.2% | 400,000 | +166.7% | 2.34% | +161.2% |
| APLS | New | APELLIS PHARMACEUTICALS INCcall | $7,037,400 | – | 185,000 | +100.0% | 2.31% | – |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $6,672,000 | +7.4% | 400,000 | +77.8% | 2.19% | +6.9% |
| COGT | Buy | COGENT BIOSCIENCES INC | $6,337,500 | -6.9% | 650,000 | +13.0% | 2.08% | -7.3% |
| RCKT | New | ROCKET PHARMACEUTICALS INCcall | $6,044,550 | – | 295,000 | +100.0% | 1.99% | – |
| AMAM | Buy | AMBRX BIOPHARMA INCsponsored ads | $6,037,500 | +54.0% | 525,000 | +120.4% | 1.99% | +53.5% |
| AKRO | Sell | AKERO THERAPEUTICS INC | $5,816,700 | -65.4% | 115,000 | -68.1% | 1.91% | -65.5% |
| IMVT | New | IMMUNOVANT INC | $4,990,700 | – | 130,000 | +100.0% | 1.64% | – |
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $4,848,800 | -50.2% | 40,000 | -52.9% | 1.60% | -50.4% |
| SNDX | New | SYNDAX PHARMACEUTICALS INCput | $4,356,000 | – | 300,000 | +100.0% | 1.43% | – |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $4,334,109 | +146.4% | 705,881 | +151.2% | 1.42% | +145.3% |
| REPL | New | REPLIMUNE GROUP INCcall | $4,277,500 | – | 250,000 | +100.0% | 1.41% | – |
| VRDN | Buy | VIRIDIAN THERAPEUTICS INC | $4,218,500 | -26.1% | 275,000 | +14.6% | 1.39% | -26.4% |
| TSHA | New | TAYSHA GENE THERAPIES INC | $4,187,000 | – | 1,325,000 | +100.0% | 1.38% | – |
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $4,134,000 | – | 325,000 | +100.0% | 1.36% | – |
| PHAT | Buy | PHATHOM PHARMACEUTICALS INC | $4,096,150 | +85.4% | 395,000 | +156.1% | 1.35% | +84.8% |
| RVNC | Sell | REVANCE THERAPEUTICS INC | $4,014,500 | -69.8% | 350,000 | -33.3% | 1.32% | -69.9% |
| Sell | AMYLYX PHARMACEUTICALS INC | $3,936,650 | -66.8% | 215,000 | -60.9% | 1.30% | -66.9% | |
| CBAY | New | CYMABAY THERAPEUTICS INCcall | $3,547,089 | – | 237,900 | +100.0% | 1.17% | – |
| XENE | Sell | XENON PHARMACEUTICALS INC | $3,380,166 | -52.5% | 98,951 | -46.5% | 1.11% | -52.7% |
| IMVT | New | IMMUNOVANT INCput | $3,263,150 | – | 85,000 | +100.0% | 1.07% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $3,016,915 | – | 101,443 | +100.0% | 0.99% | – |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $2,904,000 | -60.4% | 200,000 | -42.9% | 0.96% | -60.5% |
| IMGN | Buy | IMMUNOGEN INC | $2,777,250 | +47.2% | 175,000 | +75.0% | 0.91% | +46.5% |
| New | STRUCTURE THERAPEUTICS INCsponsored ads | $2,773,100 | – | 55,000 | +100.0% | 0.91% | – | |
| AVTE | AEROVATE THERAPEUTICS INC | $2,730,243 | -20.9% | 201,197 | 0.0% | 0.90% | -21.2% | |
| MOR | New | MORPHOSYS AGsponsored ads | $2,688,000 | – | 400,000 | +100.0% | 0.88% | – |
| CYTK | New | CYTOKINETICS INC | $2,651,400 | – | 90,000 | +100.0% | 0.87% | – |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $2,613,600 | -63.8% | 60,000 | -70.0% | 0.86% | -63.9% |
| EYPT | New | EYEPOINT PHARMACEUTICALS INC | $2,596,750 | – | 325,000 | +100.0% | 0.85% | – |
| VKTX | Sell | VIKING THERAPEUTICS INC | $2,490,750 | -76.4% | 225,000 | -65.4% | 0.82% | -76.5% |
| Sell | ASTRIA THERAPEUTICS INC | $2,238,000 | -10.5% | 300,000 | -0.1% | 0.74% | -10.8% | |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $2,128,000 | -15.3% | 175,000 | -12.5% | 0.70% | -15.6% |
| KRTX | KARUNA THERAPEUTICS INC | $2,113,625 | -22.0% | 12,500 | 0.0% | 0.70% | -22.3% | |
| New | ACELYRIN INC | $2,034,000 | – | 200,000 | +100.0% | 0.67% | – | |
| New | ACELYRIN INCput | $2,034,000 | – | 200,000 | +100.0% | 0.67% | – | |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | $2,006,000 | -28.9% | 100,000 | 0.0% | 0.66% | -29.1% | |
| BBIO | Buy | BRIDGEBIO PHARMA INC | $1,977,750 | +173.8% | 75,000 | +78.6% | 0.65% | +173.1% |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $1,667,200 | – | 80,000 | +100.0% | 0.55% | – |
| LEGN | New | LEGEND BIOTECH CORPsponsored ads | $1,511,325 | – | 22,500 | +100.0% | 0.50% | – |
| QURE | UNIQURE NV | $1,442,650 | -41.4% | 215,000 | 0.0% | 0.47% | -41.7% | |
| RCUS | ARCUS BIOSCIENCES INC | $1,346,250 | -11.6% | 75,000 | 0.0% | 0.44% | -11.9% | |
| TVTX | New | TRAVERE THERAPEUTICS INC | $1,341,000 | – | 150,000 | +100.0% | 0.44% | – |
| ARGX | New | ARGENX SEsponsored adr | $1,229,075 | – | 2,500 | +100.0% | 0.40% | – |
| New | VENTYX BIOSCIENCES INC | $1,215,550 | – | 35,000 | +100.0% | 0.40% | – | |
| AADI BIOSCIENCE INC | $1,210,000 | -29.2% | 250,000 | 0.0% | 0.40% | -29.6% | ||
| KALV | New | KALVISTA PHARMACEUTICALS INC | $963,000 | – | 100,000 | +100.0% | 0.32% | – |
| BMEA | Sell | BIOMEA FUSION INC | $894,400 | -78.6% | 65,000 | -65.8% | 0.29% | -78.6% |
| ROIVANT SCIENCES LTD | $747,520 | +15.9% | 64,000 | 0.0% | 0.25% | +15.5% | ||
| VRNA | Sell | VERONA PHARMA PLCsponsored ads | $733,500 | -68.5% | 45,000 | -59.1% | 0.24% | -68.6% |
| INBX | INHIBRX INC | $642,250 | -29.3% | 35,000 | 0.0% | 0.21% | -29.7% | |
| FUSN | Sell | FUSION PHARMACEUTICALS INC | $632,546 | -67.2% | 243,287 | -41.0% | 0.21% | -67.3% |
| ABOS | New | ACUMEN PHARMACEUTICALS INC | $622,500 | – | 150,000 | +100.0% | 0.20% | – |
| ETNB | New | 89BIO INC | $463,200 | – | 30,000 | +100.0% | 0.15% | – |
| RNA | AVIDITY BIOSCIENCES INC | $414,700 | -42.5% | 65,000 | 0.0% | 0.14% | -42.9% | |
| RAIN | RAIN ONCOLOGY INC | $280,085 | -28.2% | 325,000 | 0.0% | 0.09% | -28.7% | |
| MRSN | MERSANA THERAPEUTICS INC | $77,788 | -61.4% | 61,250 | 0.0% | 0.03% | -61.2% | |
| FGEN | Exit | FIBROGEN INC | $0 | – | -36,500 | -100.0% | -0.03% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INC | $0 | – | -31,000 | -100.0% | -0.07% | – |
| REPL | Exit | REPLIMUNE GROUP INC | $0 | – | -10,865 | -100.0% | -0.08% | – |
| PTCT | Exit | PTC THERAPEUTICS INC | $0 | – | -16,675 | -100.0% | -0.22% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -100,000 | -100.0% | -0.23% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -27,578 | -100.0% | -0.24% | – |
| BTAI | Exit | BIOXCEL THERAPEUTICS INCcall | $0 | – | -130,000 | -100.0% | -0.29% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -20,000 | -100.0% | -0.38% | – |
| BCRX | Exit | BIOCRYST PHARMACEUTICALS INC | $0 | – | -200,000 | -100.0% | -0.46% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -75,000 | -100.0% | -0.49% | – |
| VIR | Exit | VIR BIOTECHNOLOGY INC | $0 | – | -150,000 | -100.0% | -1.22% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -22,500 | -100.0% | -1.32% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -65,000 | -100.0% | -1.34% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -85,000 | -100.0% | -2.86% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -180,000 | -100.0% | -5.41% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| MIRATI THERAPEUTICS INC | 30 | Q3 2023 | 7.3% |
| ASCENDIS PHARMA A/S - ADR | 28 | Q3 2023 | 11.8% |
| BIOCRYST PHARMACEUTICALS INC | 25 | Q2 2023 | 2.4% |
| AMICUS THERAPEUTICS INC | 23 | Q3 2023 | 5.6% |
| SAREPTA THERAPEUTICS INC | 22 | Q3 2023 | 9.1% |
| SPDR SER TR | 20 | Q3 2022 | 16.9% |
| IOVANCE BIOTHERAPEUTICS INC | 18 | Q2 2023 | 5.5% |
| ROCKET PHARMACEUTICALS INC | 18 | Q2 2023 | 6.1% |
| SAGE THERAPEUTICS INC | 18 | Q1 2021 | 4.8% |
| IMMUNOMEDICS INC | 17 | Q2 2020 | 8.7% |
View Ghost Tree Capital, LLC's complete holdings history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-14 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-16 |
| 13F-HR | 2021-11-15 |
View Ghost Tree Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.