$1.43 Billion is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 134 reported holdings in Q2 2021. The portfolio turnover from Q1 2021 to Q2 2021 was 72.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | New | SPDR SER TRput | $84,625,000 | – | 625,000 | +100.0% | 5.72% | – |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $68,745,000 | +44.0% | 1,147,673 | +19.5% | 4.65% | +26.9% |
| JNJ | Sell | JOHNSON & JOHNSON | $66,820,000 | -10.4% | 405,608 | -10.6% | 4.52% | -21.0% |
| MRK | Sell | MERCK & CO INC | $60,085,000 | -3.6% | 772,601 | -4.5% | 4.06% | -15.0% |
| MRK | New | MERCK & CO INCput | $60,085,000 | – | 772,600 | +100.0% | 4.06% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $51,412,000 | – | 276,130 | +100.0% | 3.48% | – |
| SNY | Sell | SANOFIsponsored adr | $44,413,000 | -10.0% | 843,400 | -15.5% | 3.00% | -20.7% |
| GNRC | Sell | GENERAC HLDGS INC | $43,327,000 | +25.2% | 104,363 | -1.2% | 2.93% | +10.4% |
| ENPH | ENPHASE ENERGY INCcall | $42,235,000 | +13.2% | 230,000 | 0.0% | 2.86% | -0.1% | |
| LLY | Sell | LILLY ELI & CO | $41,748,000 | -47.9% | 181,895 | -57.6% | 2.82% | -54.1% |
| ABBV | Sell | ABBVIE INC | $41,248,000 | -36.4% | 366,194 | -38.9% | 2.79% | -43.9% |
| IGV | Buy | ISHARES TRput | $40,954,000 | +69.2% | 105,000 | +48.1% | 2.77% | +49.2% |
| XLK | New | SELECT SECTOR SPDR TRput | $31,009,000 | – | 210,000 | +100.0% | 2.10% | – |
| IWM | Sell | ISHARES TRput | $24,084,000 | -48.1% | 105,000 | -50.0% | 1.63% | -54.2% |
| CCCC | Buy | C4 THERAPEUTICS INC | $19,624,000 | +6.7% | 518,611 | +4.3% | 1.33% | -5.9% |
| FVRR | Sell | FIVERR INTL LTDcall | $19,157,000 | -11.8% | 79,000 | -21.0% | 1.30% | -22.2% |
| NICE | Buy | NICE LTDsponsored adr | $19,001,000 | +120.8% | 76,786 | +94.5% | 1.28% | +94.7% |
| TEVA | Buy | TEVA PHARMACEUTICAL INDS LTDcall | $18,909,000 | +84.4% | 1,910,000 | +114.9% | 1.28% | +62.5% |
| TAN | New | INVESCO EXCH TRADED FD TR IIcall | $18,759,000 | – | 210,000 | +100.0% | 1.27% | – |
| EPIX | Buy | ESSA PHARMA INC | $18,522,000 | +35.9% | 648,303 | +38.2% | 1.25% | +19.9% |
| KRNT | Sell | KORNIT DIGITAL LTD | $18,375,000 | +24.9% | 147,793 | -0.4% | 1.24% | +10.2% |
| MSFT | MICROSOFT CORP | $18,295,000 | +14.9% | 67,536 | 0.0% | 1.24% | +1.3% | |
| KURA | Buy | KURA ONCOLOGY INC | $18,116,000 | -10.7% | 868,886 | +21.1% | 1.22% | -21.3% |
| ZLAB | Buy | ZAI LAB LTDadr | $17,335,000 | +97.5% | 97,946 | +48.9% | 1.17% | +74.3% |
| BIIB | New | BIOGEN INCcall | $17,313,000 | – | 50,000 | +100.0% | 1.17% | – |
| SWTX | Buy | SPRINGWORKS THERAPEUTICS INC | $16,080,000 | +58.8% | 195,117 | +41.7% | 1.09% | +40.0% |
| FATE | Buy | FATE THERAPEUTICS INC | $14,346,000 | +58.4% | 165,299 | +50.5% | 0.97% | +39.8% |
| LPSN | Sell | LIVEPERSON INC | $14,229,000 | +3.8% | 225,000 | -13.5% | 0.96% | -8.6% |
| AMZN | Buy | AMAZON COM INC | $13,970,000 | +63.5% | 4,061 | +47.1% | 0.94% | +44.3% |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $13,597,000 | +159.7% | 302,965 | +49.9% | 0.92% | +128.9% |
| VTGN | Sell | VISTAGEN THERAPEUTICS INC | $12,854,000 | +44.5% | 4,080,673 | -2.3% | 0.87% | +27.4% |
| AUDC | Sell | AUDIOCODES LTDord | $12,746,000 | -0.7% | 385,194 | -19.0% | 0.86% | -12.4% |
| KYMR | Buy | KYMERA THERAPEUTICS INC | $12,605,000 | +31.0% | 259,895 | +5.0% | 0.85% | +15.6% |
| VRNS | Buy | VARONIS SYS INC | $12,562,000 | +76.4% | 218,013 | +57.2% | 0.85% | +55.7% |
| ONCR | Sell | ONCORUS INC | $12,331,000 | -1.9% | 893,548 | -1.1% | 0.83% | -13.5% |
| HOWL | New | WEREWOLF THERAPEUTICS INC | $12,049,000 | – | 706,294 | +100.0% | 0.82% | – |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $11,953,000 | +175.2% | 634,088 | +123.1% | 0.81% | +142.6% |
| AFMD | Buy | AFFIMED N V | $10,852,000 | +34.6% | 1,276,702 | +25.3% | 0.73% | +18.8% |
| ALXO | Buy | ALX ONCOLOGY HLDGS INC | $10,538,000 | +9.6% | 192,728 | +47.9% | 0.71% | -3.3% |
| TWLO | New | TWILIO INCcl a | $10,445,000 | – | 26,500 | +100.0% | 0.71% | – |
| RACA | Buy | THERAPEUTICS ACQUISITION COR | $10,378,000 | +37.1% | 1,009,497 | +40.2% | 0.70% | +21.0% |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $9,852,000 | – | 378,642 | +100.0% | 0.67% | – |
| CSTE | Buy | CAESARSTONE LTD | $9,508,000 | +29.4% | 644,146 | +20.4% | 0.64% | +14.0% |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $9,395,000 | -34.2% | 547,187 | -14.2% | 0.64% | -42.0% |
| FB | New | FACEBOOK INCcl a | $9,388,000 | – | 27,000 | +100.0% | 0.64% | – |
| SEDG | New | SOLAREDGE TECHNOLOGIES INC | $8,899,000 | – | 32,200 | +100.0% | 0.60% | – |
| NTLA | New | INTELLIA THERAPEUTICS INC | $8,508,000 | – | 52,550 | +100.0% | 0.58% | – |
| BIIB | Buy | BIOGEN INC | $8,309,000 | +336.9% | 23,995 | +252.9% | 0.56% | +284.9% |
| TEVA | TEVA PHARMACEUTICAL INDS LTDsponsored ads | $8,245,000 | -14.2% | 832,878 | 0.0% | 0.56% | -24.3% | |
| NAUT | New | NAUTILUS BIOTECHNOLOGY INC | $8,080,000 | – | 800,000 | +100.0% | 0.55% | – |
| NKTX | Buy | NKARTA INC | $8,001,000 | +140.8% | 252,478 | +150.0% | 0.54% | +112.2% |
| STTK | Buy | SHATTUCK LABS INC | $7,949,000 | +93.3% | 274,214 | +94.9% | 0.54% | +70.8% |
| ONTO | Sell | ONTO INNOVATION INC | $7,855,000 | -4.4% | 107,548 | -14.0% | 0.53% | -15.7% |
| STOK | Buy | STOKE THERAPEUTICS INC | $7,847,000 | +34.0% | 233,135 | +54.7% | 0.53% | +18.3% |
| DYN | Sell | DYNE THERAPEUTICS INC | $7,779,000 | +11.3% | 369,714 | -17.9% | 0.53% | -1.9% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $7,642,000 | +49.8% | 47,309 | +58.9% | 0.52% | +32.2% |
| IONS | New | IONIS PHARMACEUTICALS INCcall | $7,443,000 | – | 186,600 | +100.0% | 0.50% | – |
| BLSA | BCLS ACQUISITION CORP | $7,244,000 | -0.4% | 687,900 | 0.0% | 0.49% | -12.2% | |
| BGNE | BEIGENE LTDsponsored adr | $7,173,000 | -1.4% | 20,900 | 0.0% | 0.48% | -13.1% | |
| IDYA | Buy | IDEAYA BIOSCIENCES INC | $7,027,000 | +48.0% | 334,794 | +65.8% | 0.48% | +30.5% |
| VRNT | New | VERINT SYS INC | $6,761,000 | – | 150,000 | +100.0% | 0.46% | – |
| ALT | New | ALTIMMUNE INC | $6,731,000 | – | 683,395 | +100.0% | 0.46% | – |
| NRIX | Buy | NURIX THERAPEUTICS INC | $6,477,000 | -3.1% | 244,157 | +13.5% | 0.44% | -14.6% |
| AGIO | New | AGIOS PHARMACEUTICALS INCcall | $6,393,000 | – | 116,000 | +100.0% | 0.43% | – |
| MRUS | Buy | MERUS N V | $6,037,000 | +275.4% | 286,506 | +272.1% | 0.41% | +231.7% |
| RACB | RESEARCH ALLIANCE CORP II | $6,000,000 | -2.4% | 600,000 | 0.0% | 0.41% | -14.0% | |
| ORTX | ORCHARD THERAPEUTICS PLCads | $5,999,000 | -39.5% | 1,366,564 | 0.0% | 0.41% | -46.6% | |
| ATER | New | ATERIAN INC | $5,852,000 | – | 399,999 | +100.0% | 0.40% | – |
| STRO | SUTRO BIOPHARMA INC | $5,481,000 | -18.3% | 294,825 | 0.0% | 0.37% | -28.0% | |
| ALLT | Sell | ALLOT LTD | $5,477,000 | -18.4% | 276,187 | -34.3% | 0.37% | -28.2% |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $5,360,000 | +3.1% | 500,000 | 0.0% | 0.36% | -9.0% | |
| SBTX | Buy | SILVERBACK THERAPEUTICS INC | $5,371,000 | -26.6% | 173,891 | +3.6% | 0.36% | -35.4% |
| QURE | New | UNIQURE NV | $5,298,000 | – | 172,000 | +100.0% | 0.36% | – |
| VRNA | VERONA PHARMA PLCsponsored ads | $5,240,000 | -21.8% | 801,256 | 0.0% | 0.35% | -31.1% | |
| FVRR | New | FIVERR INTL LTD | $5,214,000 | – | 21,500 | +100.0% | 0.35% | – |
| INBX | Buy | INHIBRX INC | $5,204,000 | +126.2% | 189,083 | +64.9% | 0.35% | +100.0% |
| ATER | New | ATERIAN INCcall | $5,202,000 | – | 355,600 | +100.0% | 0.35% | – |
| CRIS | Sell | CURIS INC | $4,747,000 | -52.7% | 588,264 | -33.6% | 0.32% | -58.3% |
| CVRX | New | CVRX INC | $4,200,000 | – | 150,000 | +100.0% | 0.28% | – |
| RUN | New | SUNRUN INC | $4,016,000 | – | 72,000 | +100.0% | 0.27% | – |
| IMAB | Sell | I MABsponsored ads | $3,891,000 | +46.1% | 46,350 | -15.7% | 0.26% | +28.9% |
| SGTX | Sell | SIGILON THERAPEUTICS INC | $3,865,000 | -52.1% | 360,239 | -0.6% | 0.26% | -57.8% |
| BEAM | New | BEAM THERAPEUTICS INC | $3,659,000 | – | 28,425 | +100.0% | 0.25% | – |
| PLTK | New | PLAYTIKA HLDG CORP | $3,576,000 | – | 150,000 | +100.0% | 0.24% | – |
| ARKO | Sell | ARKO CORP | $3,399,000 | -16.2% | 369,875 | -9.3% | 0.23% | -26.0% |
| ANNX | New | ANNEXON INC | $3,339,000 | – | 148,318 | +100.0% | 0.23% | – |
| EUCR | Buy | EUCRATES BIOMEDICAL ACQU COR | $3,239,000 | +7.7% | 329,025 | +8.2% | 0.22% | -5.2% |
| ISEE | New | IVERIC BIO INC | $3,155,000 | – | 500,000 | +100.0% | 0.21% | – |
| RPTX | Sell | REPARE THERAPEUTICS INC | $3,130,000 | -58.9% | 100,391 | -59.5% | 0.21% | -63.7% |
| GRCL | Buy | GRACELL BIOTECHNOLOGIES INCsponsored ads | $3,040,000 | -7.1% | 233,850 | +10.0% | 0.21% | -17.9% |
| CYCC | CYCLACEL PHARMACEUTICALS INC | $3,009,000 | -16.7% | 508,322 | 0.0% | 0.20% | -26.4% | |
| TRMR | New | TREMOR INTL LTDads | $2,985,000 | – | 150,000 | +100.0% | 0.20% | – |
| VINC | Buy | VINCERX PHARMA INC | $2,955,000 | +63.3% | 227,450 | +142.7% | 0.20% | +43.9% |
| S | New | SENTINELONE INCcl a | $2,907,000 | – | 68,400 | +100.0% | 0.20% | – |
| ACHL | Sell | ACHILLES THERAPEUTICS PLCsponsored ads | $2,861,000 | -42.4% | 292,194 | -2.6% | 0.19% | -49.1% |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $2,872,000 | +101.4% | 84,074 | +93.9% | 0.19% | +78.0% |
| ARGX | ARGENX SEsponsored adr | $2,785,000 | +9.3% | 9,249 | 0.0% | 0.19% | -3.6% | |
| FREQ | New | FREQUENCY THERAPEUTICS INC | $2,741,000 | – | 275,160 | +100.0% | 0.18% | – |
| CYT | New | CYTEIR THERAPEUTICS INC | $2,675,000 | – | 125,000 | +100.0% | 0.18% | – |
| PRGO | New | PERRIGO CO PLC | $2,407,000 | – | 52,500 | +100.0% | 0.16% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $2,399,000 | – | 18,000 | +100.0% | 0.16% | – |
| CEREW | Sell | CEREVEL THERAPEUTICS HLDNG I*w exp 06/09/202 | $2,379,000 | +238.9% | 165,295 | -0.6% | 0.16% | +198.1% |
| IPSC | New | CENTURY THERAPEUTICS INC | $2,347,000 | – | 80,000 | +100.0% | 0.16% | – |
| LVTX | Buy | LAVA THERAPEUTICS NV | $2,343,000 | -27.9% | 215,359 | +0.7% | 0.16% | -36.5% |
| GLUE | New | MONTE ROSA THERAPEUTICS INC | $2,270,000 | – | 100,000 | +100.0% | 0.15% | – |
| TMPM | TURMERIC ACQUISITION CORPcl a | $2,170,000 | +1.2% | 219,440 | 0.0% | 0.15% | -10.4% | |
| JYAC | JIYA ACQUISITION CORP | $1,978,000 | +1.0% | 199,028 | 0.0% | 0.13% | -10.7% | |
| HCAQ | HEALTHCOR CATALIO ACQU CORP | $1,970,000 | -1.5% | 200,000 | 0.0% | 0.13% | -13.1% | |
| HCCCU | Sell | HEALTHCARE CAPITAL CORPunit 12/31/2025 | $1,962,000 | -50.3% | 196,610 | -50.8% | 0.13% | -56.1% |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $1,700,000 | – | 150,000 | +100.0% | 0.12% | – |
| WIX | WIX COM LTD | $1,655,000 | +4.0% | 5,700 | 0.0% | 0.11% | -8.2% | |
| PLRX | New | PLIANT THERAPEUTICS INC | $1,485,000 | – | 51,000 | +100.0% | 0.10% | – |
| CLRMU | Sell | CLARIM ACQUISITION CORPunit 99/99/9999 | $1,478,000 | -50.5% | 148,886 | -50.4% | 0.10% | -56.3% |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $1,480,000 | – | 53,867 | +100.0% | 0.10% | – |
| PRAX | New | PRAXIS PRECISION MEDICINES I | $1,382,000 | – | 75,600 | +100.0% | 0.09% | – |
| YMTX | Sell | YUMANITY THERAPEUTICS INC | $1,343,000 | -64.4% | 115,298 | -44.7% | 0.09% | -68.6% |
| DFPH | Sell | DFP HEALTHCARE ACQUISITNS CO | $1,257,000 | -22.5% | 126,491 | -22.3% | 0.08% | -31.5% |
| FLAC | FRAZIER LIFESCIENCES ACQU CO | $1,237,000 | -1.9% | 126,687 | 0.0% | 0.08% | -13.4% | |
| LFTR | Sell | LEFTERIS ACQUISITION CORP | $1,116,000 | -5.5% | 114,428 | -4.6% | 0.08% | -17.6% |
| CELC | New | CELCUITY INC | $1,080,000 | – | 45,000 | +100.0% | 0.07% | – |
| LCAP | Sell | LIONHEART ACQUISITION CORP I | $986,000 | +0.4% | 99,859 | -0.1% | 0.07% | -10.7% |
| OMEG | OMEGA ALPHA SPACcl a | $995,000 | +0.5% | 100,000 | 0.0% | 0.07% | -11.8% | |
| ETAC | E MERGE TECHNOLOGY ACQUISITI | $976,000 | +0.1% | 100,000 | 0.0% | 0.07% | -12.0% | |
| CMLTU | New | CM LIFE SCIENCES III INCunit 04/30/2028 | $821,000 | – | 75,000 | +100.0% | 0.06% | – |
| GRPH | New | GRAPHITE BIO INC | $767,000 | – | 24,957 | +100.0% | 0.05% | – |
| NICE SYS INCnote 1.250% 1/1 | $731,000 | +9.8% | 250,000 | 0.0% | 0.05% | -3.9% | ||
| APSG | Sell | APOLLO STRATEGIC GROWTH CAPT | $714,000 | -51.9% | 73,055 | -51.3% | 0.05% | -57.9% |
| TWNIU | Sell | TAILWIND INTERNATNAL ACQ CORunit 99/99/9999 | $483,000 | -67.5% | 48,342 | -67.8% | 0.03% | -71.1% |
| ELEV | New | ELEVATION ONCOLOGY INC | $407,000 | – | 30,000 | +100.0% | 0.03% | – |
| IMTXW | IMMATICS N.V*w exp 07/01/202 | $344,000 | +16.6% | 100,000 | 0.0% | 0.02% | 0.0% | |
| MGIC | New | MAGIC SOFTWARE ENTERPRISES Lord | $259,000 | – | 15,976 | +100.0% | 0.02% | – |
| CERE | Sell | CEREVEL THERAPEUTICS HLDNG I | $236,000 | -98.1% | 9,212 | -99.0% | 0.02% | -98.3% |
| SRSA | SARISSA CAPITAL ACQUISITN COcl a | $237,000 | -2.1% | 23,900 | 0.0% | 0.02% | -15.8% | |
| OTLKW | OUTLOOK THERAPEUTICS INC*w exp 02/18/202 | $49,000 | -62.6% | 129,500 | 0.0% | 0.00% | -70.0% | |
| NBSE | Exit | NEUBASE THERAPEUTICS INC | $0 | – | -31,900 | -100.0% | -0.02% | – |
| FTEVU | Exit | FINTECH EVOLUTION ACQUIS GROunit 99/99/9999 | $0 | – | -25,000 | -100.0% | -0.02% | – |
| NRACU | Exit | NOBLE ROCK ACQUISITION CORPunit 01/31/2028 | $0 | – | -28,000 | -100.0% | -0.02% | – |
| CMLF | Exit | CM LIFE SCIENCES INC | $0 | – | -20,000 | -100.0% | -0.02% | – |
| MDHU | Exit | MDH ACQUISITION CORPunit 99/99/9999 | $0 | – | -31,000 | -100.0% | -0.02% | – |
| AGGRU | Exit | AGILE GROWTH CORPunit 03/09/2026 | $0 | – | -50,000 | -100.0% | -0.04% | – |
| ZWRKU | Exit | Z-WORK ACQUISITION CORPunit 99/99/9999 | $0 | – | -50,000 | -100.0% | -0.04% | – |
| SCAQU | Exit | STRATIM CLOUD ACQUISITION COunit 03/05/2026 | $0 | – | -50,000 | -100.0% | -0.04% | – |
| EJFAU | Exit | EJF ACQUISITION CORPunit 03/10/2026 | $0 | – | -49,900 | -100.0% | -0.04% | – |
| VTIQU | Exit | VECTOIQ ACQUISITION CORP IIunit 99/99/9999 | $0 | – | -50,000 | -100.0% | -0.04% | – |
| SPRQ | Exit | SPARTAN ACQUISITION CORP II | $0 | – | -50,000 | -100.0% | -0.04% | – |
| LABP | Exit | LANDOS BIOPHARMA INC | $0 | – | -70,000 | -100.0% | -0.05% | – |
| LOKMU | Exit | LIVE OAK MOBILITY ACQUISI COunit 03/01/2028 | $0 | – | -75,000 | -100.0% | -0.06% | – |
| NVMI | Exit | NOVA MEASURING INSTRUMENTS L | $0 | – | -8,556 | -100.0% | -0.06% | – |
| GLHAU | Exit | GLASS HOUSES ACQUISITION CORunit 03/25/2028 | $0 | – | -89,884 | -100.0% | -0.07% | – |
| CNTB | Exit | CONNECT BIOPHARMA HLDGS LTDads | $0 | – | -50,000 | -100.0% | -0.07% | – |
| ENFAU | Exit | 890 5TH AVE PARTNERS INCunit 01/12/2026 | $0 | – | -98,828 | -100.0% | -0.08% | – |
| FCAC | Exit | FALCON CAPITAL ACQUISITN COR | $0 | – | -100,010 | -100.0% | -0.08% | – |
| MACQU | Exit | MCAP ACQUISITION CORPunit 02/18/2030 | $0 | – | -100,000 | -100.0% | -0.08% | – |
| VPCCU | Exit | VPC IMPACT ACQU HOLDI III INunit 99/99/9999 | $0 | – | -100,000 | -100.0% | -0.08% | – |
| VPCBU | Exit | VPC IMPACT ACQUISITION HLDGunit 03/05/2026 | $0 | – | -100,000 | -100.0% | -0.08% | – |
| SWBK | Exit | SWITCHBACK II CORPORATION | $0 | – | -103,698 | -100.0% | -0.08% | – |
| CAPA | Exit | HIGHCAPE CAP ACQUISITION CORcall | $0 | – | -85,000 | -100.0% | -0.08% | – |
| HSAQ | Exit | HEALTH SCIENCES ACQ CORP 2 | $0 | – | -100,000 | -100.0% | -0.09% | – |
| RAAC | Exit | REVOLUTION ACCELERTN ACQU CO | $0 | – | -109,994 | -100.0% | -0.09% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -5,530 | -100.0% | -0.09% | – |
| GMDA | Exit | GAMIDA CELL LTD | $0 | – | -178,450 | -100.0% | -0.11% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -100,000 | -100.0% | -0.11% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -23,890 | -100.0% | -0.11% | – |
| FMIVU | Exit | FORUM MERGER IV CORPunit 03/15/2028 | $0 | – | -150,000 | -100.0% | -0.11% | – |
| KURIU | Exit | ALKURI GLOBAL ACQUISITION COunit 01/01/2028 | $0 | – | -150,000 | -100.0% | -0.11% | – |
| LCAHU | Exit | LANDCADIA HOLDINGS IV INCunit 05/01/2025 | $0 | – | -150,000 | -100.0% | -0.11% | – |
| TERN | Exit | TERNS PHARMACEUTICALS INC | $0 | – | -70,000 | -100.0% | -0.12% | – |
| IMCR | Exit | IMMUNOCORE HLDGS PLCads | $0 | – | -36,000 | -100.0% | -0.12% | – |
| NSTB | Exit | NORTHERN STAR INVSTMNT CORP | $0 | – | -155,367 | -100.0% | -0.12% | – |
| KDNY | Exit | CHINOOK THERAPEUTICS INC | $0 | – | -101,666 | -100.0% | -0.12% | – |
| PIRS | Exit | PIERIS PHARMACEUTICALS INC | $0 | – | -650,000 | -100.0% | -0.13% | – |
| SVAC | Exit | STARBOARD VALUE ACQUISITN CO | $0 | – | -170,937 | -100.0% | -0.13% | – |
| GIGGU | Exit | GIGCAPITAL4 INCunit 99/99/9999 | $0 | – | -175,000 | -100.0% | -0.13% | – |
| EQ | Exit | EQUILLIUM INC | $0 | – | -254,184 | -100.0% | -0.14% | – |
| WPF | Exit | FOLEY TRASIMENE ACQUISTN COR | $0 | – | -200,000 | -100.0% | -0.15% | – |
| CAPA | Exit | HIGHCAPE CAP ACQUISITION COR | $0 | – | -172,396 | -100.0% | -0.16% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -198,260 | -100.0% | -0.16% | – |
| FNCH | Exit | FINCH THERAPEUTICS GROUP INC | $0 | – | -150,000 | -100.0% | -0.18% | – |
| CAMT | Exit | CAMTEK LTDord | $0 | – | -79,746 | -100.0% | -0.18% | – |
| TIL | Exit | INSTIL BIO INC | $0 | – | -95,000 | -100.0% | -0.18% | – |
| LSAQ | Exit | LIFESCI ACQUISITION II CORP | $0 | – | -244,000 | -100.0% | -0.19% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -158,500 | -100.0% | -0.20% | – |
| PHAS | Exit | PHASEBIO PHARMACEUTICALS INC | $0 | – | -750,000 | -100.0% | -0.20% | – |
| GLTO | Exit | GALECTO INC | $0 | – | -448,016 | -100.0% | -0.21% | – |
| GRTX | Exit | GALERA THERAPEUTICS INC | $0 | – | -323,348 | -100.0% | -0.22% | – |
| LGVU | Exit | LONGVIEW ACQUISITION CORP IIunit 99/99/9999 | $0 | – | -300,000 | -100.0% | -0.23% | – |
| EWTX | Exit | EDGEWISE THERAPEUTICS INC | $0 | – | -100,000 | -100.0% | -0.25% | – |
| Exit | CATABASIS PHARMACEUTICALS IN | $0 | – | -1,294,000 | -100.0% | -0.29% | – | |
| IFRX | Exit | INFLARX NV | $0 | – | -1,000,000 | -100.0% | -0.30% | – |
| FOREU | Exit | FORESIGHT ACQUISITION CORPunit 01/29/2026 | $0 | – | -420,000 | -100.0% | -0.32% | – |
| ORIC | Exit | ORIC PHARMACEUTICALS INC | $0 | – | -169,900 | -100.0% | -0.32% | – |
| FTCH | Exit | FARFETCH LTDord sh cl a | $0 | – | -80,000 | -100.0% | -0.32% | – |
| CLOU | Exit | GLOBAL X FDSput | $0 | – | -170,600 | -100.0% | -0.34% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -1,312,415 | -100.0% | -0.34% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -220,320 | -100.0% | -0.35% | – |
| RTPZ | Exit | REINVENT TECHNOLOGY PARTNERS | $0 | – | -468,012 | -100.0% | -0.36% | – |
| RADA | Exit | RADA ELECTR INDS LTD | $0 | – | -407,925 | -100.0% | -0.38% | – |
| BIDU | Exit | BAIDU INCspon adr rep a | $0 | – | -25,000 | -100.0% | -0.42% | – |
| ARYA | Exit | ARYA SCIENCES ACQUISITION CO | $0 | – | -400,000 | -100.0% | -0.42% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -145,476 | -100.0% | -0.50% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -258,880 | -100.0% | -0.51% | – |
| COGT | Exit | UNUM THERAPEUTICS INC | $0 | – | -762,569 | -100.0% | -0.51% | – |
| CYBR | Exit | CYBERARK SOFTWARE LTD | $0 | – | -55,000 | -100.0% | -0.55% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -670,459 | -100.0% | -0.55% | – | |
| MWK | Exit | MOHAWK GROUP HLDGS INC | $0 | – | -251,015 | -100.0% | -0.57% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INC | $0 | – | -175,140 | -100.0% | -0.58% | – |
| BOLT | Exit | BOLT BIOTHERAPEUTICS INC | $0 | – | -241,000 | -100.0% | -0.61% | – |
| TLT | Exit | ISHARES TRput | $0 | – | -60,000 | -100.0% | -0.62% | – |
| PRGO | Exit | PERRIGO CO PLCcall | $0 | – | -210,000 | -100.0% | -0.65% | – |
| ICLN | Exit | ISHARES TRput | $0 | – | -420,000 | -100.0% | -0.78% | – |
| PANW | Exit | PALO ALTO NETWORKS INC | $0 | – | -32,300 | -100.0% | -0.80% | – |
| MWK | Exit | MOHAWK GROUP HLDGS INCcall | $0 | – | -355,600 | -100.0% | -0.80% | – |
| BMY | Exit | BRISTOL-MYERS SQUIBB CO | $0 | – | -200,000 | -100.0% | -0.97% | – |
| JNJ | Exit | JOHNSON & JOHNSONcall | $0 | – | -200,000 | -100.0% | -2.52% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
- Sphera Global Healthcare GP Ltd #1
- Sphera Global Healthcare Management LP #2
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-08-17
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.