$4.8 Billion is the total value of RTW INVESTMENTS, LP's 60 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 42.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RXDX | Sell | PROMETHEUS BIOSCIENCES INC | $351,162,201 | -4.8% | 3,272,104 | -2.5% | 7.31% | -2.9% |
| PTCT | Buy | PTC THERAPEUTICS INC | $343,599,355 | +60.3% | 7,093,298 | +26.3% | 7.16% | +63.5% |
| ALNY | ALNYLAM PHARMACEUTICALS INC | $337,211,076 | -15.7% | 1,683,362 | 0.0% | 7.02% | -14.0% | |
| RCKT | ROCKET PHARMACEUTICALS INC | $302,991,534 | -12.5% | 17,687,772 | 0.0% | 6.31% | -10.7% | |
| IMCR | Buy | IMMUNOCORE HLDGS PLCads | $279,333,182 | -12.0% | 5,649,943 | +1.6% | 5.82% | -10.2% |
| MASI | MASIMO CORP | $277,085,518 | +24.7% | 1,501,493 | 0.0% | 5.77% | +27.2% | |
| AXSM | Buy | AXSOME THERAPEUTICS INC | $233,203,136 | +1.4% | 3,780,855 | +26.9% | 4.86% | +3.5% |
| PEN | Sell | PENUMBRA INC | $187,661,764 | +20.8% | 673,371 | -3.6% | 3.91% | +23.2% |
| ARGX | ARGENX SEsponsored adr | $179,656,213 | -1.6% | 482,195 | 0.0% | 3.74% | +0.3% | |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $171,266,940 | -6.8% | 4,270,996 | +7.7% | 3.57% | -5.0% |
| TMO | Sell | THERMO FISHER SCIENTIFIC INC | $167,339,808 | -30.2% | 290,334 | -33.3% | 3.48% | -28.8% |
| ESTA | Buy | ESTABLISHMENT LABS HLDGS INC | $161,840,208 | +3.8% | 2,389,138 | +0.6% | 3.37% | +5.9% |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC C | $155,130,700 | +165.4% | 8,242,864 | +124.5% | 3.23% | +170.7% |
| NTRA | Buy | NATERA INC | $145,006,192 | +38.3% | 2,611,783 | +0.1% | 3.02% | +41.1% |
| MRTX | MIRATI THERAPEUTICS INC | $135,450,979 | -17.9% | 3,643,114 | 0.0% | 2.82% | -16.3% | |
| CLDX | CELLDEX THERAPEUTICS INC NEW | $110,970,056 | -19.3% | 3,084,215 | 0.0% | 2.31% | -17.6% | |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $105,818,377 | +170.0% | 4,600,799 | +28.1% | 2.20% | +175.5% |
| New | ORCHESTRA BIOMED HLDGS INC | $100,169,182 | – | 5,118,507 | +100.0% | 2.09% | – | |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $98,043,182 | -21.2% | 6,387,178 | +13.9% | 2.04% | -19.6% |
| VCEL | Buy | VERICEL CORP | $96,517,716 | +18.2% | 3,291,873 | +6.2% | 2.01% | +20.6% |
| BRKR | New | BRUKER CORP | $93,610,043 | – | 1,187,342 | +100.0% | 1.95% | – |
| CYTK | CYTOKINETICS INC | $90,586,028 | -23.2% | 2,574,198 | 0.0% | 1.89% | -21.7% | |
| ILMN | Sell | ILLUMINA INC | $87,496,938 | -23.3% | 376,250 | -33.3% | 1.82% | -21.8% |
| AVDL | AVADEL PHARMACEUTICALS PLCsponsored adr | $52,596,161 | +27.9% | 5,741,939 | 0.0% | 1.10% | +30.5% | |
| TXG | Buy | 10X GENOMICS INC | $51,844,866 | +63.0% | 929,286 | +6.5% | 1.08% | +66.4% |
| AXNX | AXONICS INC | $48,284,181 | -12.7% | 884,974 | 0.0% | 1.00% | -11.1% | |
| Sell | VENTYX BIOSCIENCES INC | $46,527,514 | -8.6% | 1,388,881 | -10.5% | 0.97% | -6.7% | |
| CUTR | Buy | CUTERA INC | $43,616,598 | -45.2% | 1,846,596 | +2.7% | 0.91% | -44.1% |
| STOK | Buy | STOKE THERAPEUTICS INC | $36,573,348 | +2.4% | 4,390,558 | +13.4% | 0.76% | +4.5% |
| TARS | TARSUS PHARMACEUTICALS INC | $32,029,931 | -14.3% | 2,548,125 | 0.0% | 0.67% | -12.6% | |
| SCPH | New | SCPHARMACEUTICALS INC | $29,911,436 | – | 3,297,843 | +100.0% | 0.62% | – |
| ACET | ADICET BIO INC | $24,430,879 | -35.6% | 4,241,472 | 0.0% | 0.51% | -34.2% | |
| GHRS | GH RESEARCH PLCordinary shares | $17,329,966 | -17.8% | 2,168,957 | 0.0% | 0.36% | -16.0% | |
| VKTX | New | VIKING THERAPEUTICS INC | $16,650,000 | – | 1,000,000 | +100.0% | 0.35% | – |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $15,708,741 | -56.8% | 5,511,839 | +10.4% | 0.33% | -55.9% |
| OM | Sell | OUTSET MED INC | $14,879,307 | -36.6% | 808,658 | -11.1% | 0.31% | -35.3% |
| OLK | Sell | OLINK HLDG ABsponsored ads | $14,748,408 | -40.8% | 654,612 | -33.3% | 0.31% | -39.7% |
| New | MINERALYS THERAPEUTICS INC | $14,440,086 | – | 922,100 | +100.0% | 0.30% | – | |
| PMVP | Sell | PMV PHARMACEUTICALS INC | $14,305,697 | -62.3% | 2,999,098 | -31.2% | 0.30% | -61.5% |
| MIST | Sell | MILESTONE PHARMACEUTICALS IN | $12,829,042 | -24.9% | 3,256,102 | -24.5% | 0.27% | -23.5% |
| Buy | ROIVANT SCIENCES LTD | $11,459,051 | +78.7% | 1,552,717 | +93.4% | 0.24% | +82.4% | |
| MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $10,695,000 | +103.7% | 500,000 | 0.0% | 0.22% | +108.4% | ||
| GH | GUARDANT HEALTH INC | $10,099,991 | -13.8% | 430,887 | 0.0% | 0.21% | -12.1% | |
| DERMTECH INC | $10,003,550 | +107.9% | 2,718,356 | 0.0% | 0.21% | +112.2% | ||
| APYX | APYX MEDICAL CORPORATION | $9,787,044 | +23.1% | 3,398,279 | 0.0% | 0.20% | +25.9% | |
| URGN | UROGEN PHARMA LTD | $7,922,967 | +4.2% | 857,464 | 0.0% | 0.16% | +6.5% | |
| IMUX | Buy | IMMUNIC INC | $6,398,744 | +18.4% | 4,294,459 | +11.2% | 0.13% | +20.9% |
| ALLK | Sell | ALLAKOS INC | $5,903,406 | -57.3% | 1,326,608 | -19.3% | 0.12% | -56.4% |
| CSTL | Sell | CASTLE BIOSCIENCES INC | $5,873,075 | -51.7% | 258,498 | -50.0% | 0.12% | -50.8% |
| IMTX | IMMATICS N.V | $5,830,500 | -20.8% | 845,000 | 0.0% | 0.12% | -19.3% | |
| RLMD | Buy | RELMADA THERAPEUTICS INC | $4,817,947 | -33.2% | 2,131,835 | +3.1% | 0.10% | -32.0% |
| New | JASPER THERAPEUTICS INC | $4,216,954 | – | 2,329,809 | +100.0% | 0.09% | – | |
| XGN | Buy | EXAGEN INC | $3,380,577 | +3.2% | 1,391,184 | +2.0% | 0.07% | +4.5% |
| AKYA | Sell | AKOYA BIOSCIENCES INC | $2,686,492 | -42.0% | 328,422 | -32.1% | 0.06% | -41.1% |
| Sell | THIRD HARMONIC BIO INC | $2,202,910 | -16.0% | 534,687 | -12.3% | 0.05% | -14.8% | |
| ARYD | Sell | ARYA SCIENCES ACQU CORP IVcl a | $1,324,490 | -73.8% | 127,970 | -74.4% | 0.03% | -72.8% |
| MIRO | Buy | MIROMATRIX MED INC | $747,973 | -10.7% | 445,222 | +59.0% | 0.02% | -5.9% |
| New | YS BIOPHARMA CO LTDordinary shares | $545,744 | – | 341,090 | +100.0% | 0.01% | – | |
| Sell | SIGHT SCIENCES INC | $361,224 | -95.6% | 41,330 | -93.8% | 0.01% | -95.2% | |
| New | ROCKET PHARMACEUTICALS INC*w exp 09/02/202 | $38,500 | – | 350,000 | +100.0% | 0.00% | – | |
| MSACW | Exit | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $0 | – | -33,331 | -100.0% | 0.00% | – |
| Exit | SCIENCE 37 HOLDINGS INC | $0 | – | -2,586,108 | -100.0% | -0.02% | – | |
| NAUT | Exit | NAUTILUS BIOTECHNOLOGY INC | $0 | – | -600,000 | -100.0% | -0.02% | – |
| Exit | NYXOAH S A | $0 | – | -269,993 | -100.0% | -0.03% | – | |
| LUNG | Exit | PULMONX CORP | $0 | – | -275,000 | -100.0% | -0.05% | – |
| MASS | Exit | 908 DEVICES INC | $0 | – | -312,000 | -100.0% | -0.05% | – |
| MSAC | Exit | MEDICUS SCIENCES ACQUISITION | $0 | – | -300,000 | -100.0% | -0.06% | – |
| JNJ | Exit | JOHNSON & JOHNSON | $0 | – | -18,127 | -100.0% | -0.06% | – |
| BWAY | Exit | BRAINSWAY LTDsponsored ads | $0 | – | -1,602,381 | -100.0% | -0.08% | – |
| TELA | Exit | TELA BIO INC | $0 | – | -390,364 | -100.0% | -0.09% | – |
| Exit | TENAYA THERAPEUTICS INC | $0 | – | -2,458,750 | -100.0% | -0.10% | – | |
| SMIHU | Exit | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $0 | – | -500,000 | -100.0% | -0.10% | – |
| Exit | ARYA SCIENCES ACQUISITN CORP | $0 | – | -500,000 | -100.0% | -0.10% | – | |
| JNCE | Exit | JOUNCE THERAPEUTICS INC | $0 | – | -5,106,341 | -100.0% | -0.12% | – |
| GLUE | Exit | MONTE ROSA THERAPEUTICS INC | $0 | – | -1,214,572 | -100.0% | -0.19% | – |
| Exit | AADI BIOSCIENCE INC | $0 | – | -764,701 | -100.0% | -0.20% | – | |
| HSAQ | Exit | HEALTH SCIENCES ACQ CORP 2 | $0 | – | -1,000,000 | -100.0% | -0.20% | – |
| TERN | Exit | TERNS PHARMACEUTICALS INC | $0 | – | -1,000,000 | -100.0% | -0.21% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -2,819,472 | -100.0% | -0.34% | – |
| Exit | CINCOR PHARMA INC | $0 | – | -1,389,705 | -100.0% | -0.35% | – | |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -821,288 | -100.0% | -0.36% | – |
| OYST | Exit | OYSTER PT PHARMA INC | $0 | – | -2,304,977 | -100.0% | -0.53% | – |
| BCYC | Exit | BICYCLE THERAPEUTICS PLCsponsored ads | $0 | – | -1,258,587 | -100.0% | -0.76% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -1,845,366 | -100.0% | -0.85% | – |
| GMED | Exit | GLOBUS MED INCcl a | $0 | – | -747,685 | -100.0% | -1.13% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.