$334 Million is the total value of DAFNA Capital Management LLC's 72 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 19.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | Buy | SPDR S&P BIOTECH ETFetf | $43,439,700 | -7.5% | 570,000 | +0.7% | 13.02% | -1.6% |
| STXS | STEREOTAXIS INC | $27,908,330 | -1.4% | 13,680,554 | 0.0% | 8.37% | +4.9% | |
| ISEE | Buy | IVERIC BIO INC | $14,913,682 | +15.0% | 612,975 | +1.2% | 4.47% | +22.4% |
| ASND | Buy | ASCENDIS PHARMA A/Ssponsored adr | $14,497,431 | -8.8% | 135,212 | +3.8% | 4.35% | -2.9% |
| KRTX | Buy | KARUNA THERAPEUTICS INC | $14,272,000 | +0.8% | 78,573 | +9.1% | 4.28% | +7.4% |
| IBB | ISHARES NASDAQ BIOTECH INDXetf | $13,238,900 | -1.6% | 102,500 | 0.0% | 3.97% | +4.7% | |
| RVMD | Buy | REVOLUTION MEDICINES INC | $12,471,503 | +9.6% | 575,785 | +20.5% | 3.74% | +16.7% |
| BPMC | BLUEPRINT MEDICINES CORP | $11,752,963 | +2.7% | 261,235 | 0.0% | 3.52% | +9.3% | |
| XENE | XENON PHARMACEUTICALS INC | $11,312,933 | -9.2% | 316,092 | 0.0% | 3.39% | -3.4% | |
| CYTK | Buy | CYTOKINETICS INC | $9,729,859 | +15.4% | 276,495 | +50.3% | 2.92% | +22.9% |
| SNDX | SYNDAX PHARMACEUTICALS INC | $9,442,182 | -17.0% | 447,073 | 0.0% | 2.83% | -11.7% | |
| DXCM | DEXCOM INC | $7,848,191 | +2.6% | 67,552 | 0.0% | 2.35% | +9.2% | |
| SAGE | SAGE THERAPEUTICS INC | $7,565,640 | +10.0% | 180,306 | 0.0% | 2.27% | +17.1% | |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $7,552,530 | -13.5% | 74,615 | +2.0% | 2.26% | -8.0% |
| MORF | Sell | MORPHIC HOLDING INC | $6,755,138 | +29.2% | 179,467 | -8.2% | 2.02% | +37.5% |
| IDYA | IDEAYA BIOSCIENCES INC | $6,430,555 | -24.4% | 468,358 | 0.0% | 1.93% | -19.6% | |
| CSII | CARDIOVASCULAR SYSTEMS | $5,699,582 | +45.8% | 286,988 | 0.0% | 1.71% | +55.2% | |
| Buy | DICE THERAPEUTICS INC | $5,374,310 | +39.5% | 187,585 | +51.9% | 1.61% | +48.5% | |
| VKTX | Sell | VIKING THERAPEUTICS INC | $5,313,931 | +8.4% | 319,155 | -38.8% | 1.59% | +15.4% |
| MRUS | Buy | MERUS N V | $5,225,563 | +25.2% | 283,998 | +5.2% | 1.57% | +33.2% |
| ATRC | Buy | ATRICURE INC | $5,203,177 | +62.8% | 125,529 | +74.3% | 1.56% | +73.3% |
| NRIX | NURIX THERAPEUTICS INC | $5,032,252 | -19.1% | 566,695 | 0.0% | 1.51% | -13.9% | |
| EWTX | Sell | EDGEWISE THERAPEUTICS INC | $4,890,704 | -28.7% | 733,239 | -4.4% | 1.47% | -24.1% |
| KALV | KALVISTA PHARMACEUTICALS INC | $4,842,012 | +16.3% | 616,032 | 0.0% | 1.45% | +23.8% | |
| BCRX | Buy | BIOCRYST PHARMACEUTICALS INC | $4,599,510 | +59.6% | 551,500 | +119.7% | 1.38% | +69.8% |
| ACET | Buy | ADICET BIO INC | $4,591,031 | -18.7% | 797,054 | +26.2% | 1.38% | -13.5% |
| IPSC | Buy | CENTURY THERAPEUTICS INC | $4,536,702 | +86.0% | 1,307,407 | +175.0% | 1.36% | +98.0% |
| APLS | Sell | APELLIS PHARMACEUTICALS INC | $3,808,926 | -11.7% | 57,746 | -30.8% | 1.14% | -6.0% |
| ALEC | Buy | ALECTOR INC | $3,667,191 | -25.4% | 592,438 | +11.3% | 1.10% | -20.6% |
| ARAY | ACCURAY INC | $3,630,403 | +42.1% | 1,222,358 | 0.0% | 1.09% | +51.1% | |
| Buy | MEDIWOUND LTD | $3,431,938 | +24.7% | 257,653 | +26.2% | 1.03% | +32.8% | |
| Sell | BIOHAVEN LTD | $3,218,474 | -41.0% | 235,613 | -40.1% | 0.96% | -37.2% | |
| RCUS | Buy | ARCUS BIOSCIENCES INC | $3,195,958 | +8.7% | 175,217 | +23.2% | 0.96% | +15.7% |
| AXGN | AXOGEN INC | $3,138,373 | -5.3% | 332,103 | 0.0% | 0.94% | +0.9% | |
| MRTX | MIRATI THERAPEUTICS INC | $2,736,448 | -17.9% | 73,600 | 0.0% | 0.82% | -12.7% | |
| BCYC | BICYCLE THERAPEUTICS PLCsponsored ads | $2,599,194 | -28.1% | 122,200 | 0.0% | 0.78% | -23.6% | |
| AUTL | AUTOLUS THERAPEUTICS PLCspon ads | $2,164,116 | -3.2% | 1,176,150 | 0.0% | 0.65% | +3.2% | |
| MRSN | Buy | MERSANA THERAPEUTICS INC | $2,099,647 | -13.3% | 510,863 | +23.6% | 0.63% | -7.6% |
| GLPG | GALAPAGOS NVspon adr | $2,035,362 | -12.9% | 52,675 | 0.0% | 0.61% | -7.3% | |
| PRQR | New | PROQR THERAPEUTICS N V | $2,003,440 | – | 940,582 | +100.0% | 0.60% | – |
| Buy | VIGIL NEUROSCIENCE INC | $1,686,895 | -20.1% | 172,308 | +2.1% | 0.51% | -14.8% | |
| KURA | Sell | KURA ONCOLOGY INC | $1,342,658 | -25.3% | 109,784 | -24.2% | 0.40% | -20.4% |
| ITOS | ITEOS THERAPEUTICS INC | $1,341,402 | -30.3% | 98,560 | 0.0% | 0.40% | -25.8% | |
| Buy | THESEUS PHARMACEUTICALS INC | $1,163,502 | +185.4% | 131,025 | +60.1% | 0.35% | +203.5% | |
| LRMR | Sell | LARIMAR THERAPEUTICS INC | $1,073,035 | -45.1% | 236,873 | -49.9% | 0.32% | -41.5% |
| ORIC | Sell | ORIC PHARMACEUTICALS INC | $970,858 | -37.6% | 170,326 | -35.5% | 0.29% | -33.6% |
| New | ASTRIA THERAPEUTICS INC | $929,444 | – | 69,883 | +100.0% | 0.28% | – | |
| STIM | NEURONETICS INC | $912,916 | -57.6% | 313,717 | 0.0% | 0.27% | -54.9% | |
| BWAY | Buy | BRAINSWAY LTDsponsored ads | $831,837 | +53.1% | 473,981 | +115.4% | 0.25% | +62.7% |
| KROS | Sell | KEROS THERAPEUTICS INC | $826,715 | -47.8% | 19,361 | -41.3% | 0.25% | -44.4% |
| GNFT | GENFIT S Aads | $811,554 | -6.6% | 197,940 | 0.0% | 0.24% | -0.8% | |
| MREO | MEREO BIOPHARMA GROUP PLCspon ads | $775,125 | -5.7% | 1,096,513 | 0.0% | 0.23% | 0.0% | |
| SURF | Buy | SURFACE ONCOLOGY INC | $768,680 | +19.7% | 1,100,000 | +40.5% | 0.23% | +27.1% |
| KPTI | KARYOPHARM THERAPEUTICS INC | $749,517 | +14.4% | 192,678 | 0.0% | 0.22% | +21.6% | |
| SYROS PHARMACEUTICALS INC | $709,894 | -25.6% | 265,878 | 0.0% | 0.21% | -20.8% | ||
| SPRB | New | SPRUCE BIOSCIENCES INC | $689,520 | – | 312,000 | +100.0% | 0.21% | – |
| Buy | ACRIVON THERAPEUTICS INC | $649,068 | +260.1% | 51,148 | +226.9% | 0.20% | +282.4% | |
| PARDES BIOSCIENCES INC | $632,790 | -21.9% | 479,386 | 0.0% | 0.19% | -16.7% | ||
| MASI | MASIMO CORP | $553,620 | +24.7% | 3,000 | 0.0% | 0.17% | +32.8% | |
| KNTE | Buy | KINNATE BIOPHARMA INC | $506,300 | +16.9% | 81,008 | +14.1% | 0.15% | +24.6% |
| REGULUS THERAPEUTICS INC | $470,833 | -38.1% | 555,555 | 0.0% | 0.14% | -34.1% | ||
| MDNA | MEDICENNA THERAPEUTICS CORP | $415,536 | +37.5% | 660,000 | 0.0% | 0.12% | +47.1% | |
| IKNA | Sell | IKENA ONCOLOGY INC | $389,629 | +19.6% | 112,936 | -7.8% | 0.12% | +27.2% |
| STRO | New | SUTRO BIOPHARMA INC | $391,314 | – | 84,700 | +100.0% | 0.12% | – |
| ADAP | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $382,660 | -25.3% | 351,064 | 0.0% | 0.12% | -20.1% | |
| CMPX | Sell | COMPASS THERAPEUTICS INC | $382,204 | -87.4% | 116,882 | -80.6% | 0.12% | -86.5% |
| NXTC | NEXTCURE INC | $277,790 | +5.0% | 187,696 | 0.0% | 0.08% | +10.7% | |
| LCTX | LINEAGE CELL THERAPEUTICS IN | $210,000 | +28.2% | 140,000 | 0.0% | 0.06% | +37.0% | |
| INGN | INOGEN INC | $187,200 | -36.7% | 15,000 | 0.0% | 0.06% | -32.5% | |
| SPRO | SPERO THERAPEUTICS INC | $181,250 | -16.2% | 125,000 | 0.0% | 0.05% | -11.5% | |
| CGEN | COMPUGEN LTDord | $144,052 | -1.9% | 205,202 | 0.0% | 0.04% | +4.9% | |
| Sell | REUNION NEUROSCIENCE INC | $8,698 | -79.7% | 12,598 | -73.6% | 0.00% | -75.0% | |
| PHAS | Exit | PHASEBIO PHARMACEUTICALS INC | $0 | – | -321,856 | -100.0% | -0.00% | – |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -97,500 | -100.0% | -0.05% | – |
| SCYX | Exit | SCYNEXIS INC | $0 | – | -153,269 | -100.0% | -0.07% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -39,879 | -100.0% | -0.08% | – |
| BMEA | Exit | BIOMEA FUSION INC | $0 | – | -34,625 | -100.0% | -0.08% | – |
| Exit | CINCOR PHARMA INC | $0 | – | -48,000 | -100.0% | -0.17% | – | |
| AFMD | Exit | AFFIMED N V | $0 | – | -686,282 | -100.0% | -0.24% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -171,059 | -100.0% | -0.30% | – |
| FSTX | Exit | F-STAR THERAPEUTICS INC | $0 | – | -576,881 | -100.0% | -1.03% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -324,173 | -100.0% | -1.16% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -550,940 | -100.0% | -1.57% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| STEREOTAXIS INC | 42 | Q3 2023 | 27.6% |
| ATRICURE INC | 42 | Q3 2023 | 11.4% |
| MASIMO CORPORATION | 42 | Q3 2023 | 1.8% |
| ASCENDIS PHARMA A S SPONSORED | 34 | Q3 2023 | 4.5% |
| AERIE PHARMACEUTICALS INC | 33 | Q3 2022 | 4.2% |
| GALAPAGOS NV-SPON ADR | 33 | Q3 2023 | 3.8% |
| XENON PHARMACEUTICALS INC | 33 | Q3 2023 | 3.6% |
| NEUROCRINE BIOSCIENCES INC | 32 | Q3 2023 | 2.9% |
| JOHNSON AND JOHNSON | 32 | Q1 2021 | 1.2% |
| ISHARES TR NASDQ BIOTECH | 30 | Q3 2023 | 4.0% |
View DAFNA Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Stereotaxis, Inc. | March 08, 2018 | 13,680,554 | 23.4% |
| SUNESIS PHARMACEUTICALS INC | February 14, 2018 | 983,000 | 2.9% |
| SUNESIS PHARMACEUTICALS INC | February 14, 2017 | 1,133,583 | 5.4% |
| WINDTREE THERAPEUTICS INC /DE/ | February 14, 2017 | 208,333 | 2.4% |
| ANAVEX LIFE SCIENCES CORP.Sold out | February 16, 2016 | 0 | 0.0% |
| DISCOVERY LABORATORIES INC /DE/ | February 16, 2016 | 10,658,699 | 9.2% |
| PRECISION OPTICS CORPORATION, INC. | February 13, 2015 | 311,537 | 5.0% |
| TearLab Corp | February 14, 2013 | 939,239 | 3.2% |
| VIKING SYSTEMS INC | February 14, 2012 | 3,781,468 | 5.2% |
View DAFNA Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| SC 13G/A | 2023-02-14 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-14 |
| 13F-HR | 2022-08-15 |
View DAFNA Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.