$4.58 Billion is the total value of RA Capital Management's 96 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 21.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/Ssponsored adr | $888,169 | -12.8% | 7,567,900 | 0.0% | 19.38% | +8.0% | |
| BIIB | New | BIOGEN INC | $153,111 | – | 727,024 | +100.0% | 3.34% | – |
| AVTE | AEROVATE THERAPEUTICS INC | $151,479 | +55.5% | 8,263,982 | 0.0% | 3.30% | +92.4% | |
| Buy | CYTEK BIOSCIENCES INC | $144,248 | -8.0% | 13,381,054 | +39.3% | 3.15% | +13.9% | |
| ITOS | ITEOS THERAPEUTICS INC | $142,147 | -30.9% | 4,417,259 | 0.0% | 3.10% | -14.5% | |
| TVTX | Sell | TRAVERE THERAPEUTICS INC | $126,864 | -27.2% | 4,922,941 | -12.3% | 2.77% | -9.9% |
| JANX | JANUX THERAPEUTICS INC | $124,337 | -27.3% | 8,670,644 | 0.0% | 2.71% | -10.0% | |
| PCVX | Buy | VAXCYTE INC | $110,636 | +9.7% | 4,581,203 | +8.0% | 2.41% | +35.7% |
| ELIEM THERAPEUTICS INC | $110,336 | -19.8% | 13,150,849 | 0.0% | 2.41% | -0.7% | ||
| IMGN | Buy | IMMUNOGEN INC | $103,489 | -31.1% | 21,741,458 | +7.4% | 2.26% | -14.7% |
| DICE THERAPEUTICS INC | $99,646 | -24.4% | 5,208,911 | 0.0% | 2.17% | -6.5% | ||
| GHRS | Buy | GH RESEARCH PLCordinary shares | $88,292 | +33.1% | 4,827,330 | +69.8% | 1.93% | +64.6% |
| FMTX | FORMA THERAPEUTICS HLDGS INC | $83,808 | -34.6% | 9,011,651 | 0.0% | 1.83% | -19.0% | |
| TYRA BIOSCIENCES INC | $77,430 | -24.0% | 7,236,454 | 0.0% | 1.69% | -5.9% | ||
| PNT | POINT BIOPHARMA GLOBAL INC | $71,754 | +42.3% | 9,003,018 | 0.0% | 1.57% | +76.2% | |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $70,675 | +1.3% | 2,075,000 | +15.0% | 1.54% | +25.4% |
| BLU | BELLUS HEALTH INC NEW | $70,384 | -14.5% | 10,230,274 | 0.0% | 1.54% | +5.8% | |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $68,633 | – | 964,212 | +100.0% | 1.50% | – |
| VOR | VOR BIOPHARMA INC | $67,171 | -48.0% | 11,120,973 | 0.0% | 1.47% | -35.6% | |
| NKTX | NKARTA INC | $63,786 | -25.9% | 5,605,129 | 0.0% | 1.39% | -8.2% | |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $60,378 | +8.0% | 734,343 | +92.7% | 1.32% | +33.7% |
| DAWN | Buy | DAY ONE BIOPHARMACEUTICALS I | $60,116 | -28.2% | 6,060,090 | +22.0% | 1.31% | -11.1% |
| RYTM | RHYTHM PHARMACEUTICALS INC | $56,115 | +15.4% | 4,871,067 | 0.0% | 1.22% | +42.8% | |
| New | AN2 THERAPEUTICS INC | $55,257 | – | 3,666,663 | +100.0% | 1.21% | – | |
| RLMD | RELMADA THERAPEUTICS INC | $53,980 | +19.8% | 2,000,000 | 0.0% | 1.18% | +48.4% | |
| MGNX | MACROGENICS INC | $53,773 | -45.1% | 6,103,594 | 0.0% | 1.17% | -32.1% | |
| NTRA | New | NATERA INC | $53,303 | – | 1,310,289 | +100.0% | 1.16% | – |
| TIL | INSTIL BIO INC | $52,361 | -37.2% | 4,870,793 | 0.0% | 1.14% | -22.3% | |
| NVAX | Sell | NOVAVAX INC | $51,024 | -83.0% | 692,794 | -67.0% | 1.11% | -79.0% |
| KNTE | Buy | KINNATE BIOPHARMA INC | $48,014 | -24.6% | 4,264,144 | +18.7% | 1.05% | -6.7% |
| VERA | New | VERA THERAPEUTICS INCcl a | $46,183 | – | 1,966,084 | +100.0% | 1.01% | – |
| Buy | PARDES BIOSCIENCES INC | $44,584 | -12.9% | 6,175,038 | +97.5% | 0.97% | +7.8% | |
| Buy | ICOSAVAX INC | $41,983 | -68.3% | 5,963,565 | +3.2% | 0.92% | -60.7% | |
| TENAYA THERAPEUTICS INC | $41,837 | -37.8% | 3,551,508 | 0.0% | 0.91% | -23.1% | ||
| EYPT | EYEPOINT PHARMACEUTICALS INC | $40,952 | -0.7% | 3,370,506 | 0.0% | 0.89% | +23.0% | |
| GERN | GERON CORP | $40,972 | +11.5% | 30,126,299 | 0.0% | 0.89% | +38.0% | |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $40,032 | +297.6% | 2,167,391 | +411.6% | 0.87% | +390.4% |
| ABOS | ACUMEN PHARMACEUTICALS INC | $38,204 | -42.2% | 9,770,773 | 0.0% | 0.83% | -28.4% | |
| RXSIGHT INC | $37,794 | +10.0% | 3,052,796 | 0.0% | 0.82% | +36.1% | ||
| PMVP | PMV PHARMACEUTICALS INC | $35,608 | -9.9% | 1,710,265 | 0.0% | 0.78% | +11.5% | |
| DSGN | DESIGN THERAPEUTICS INC | $35,314 | -24.6% | 2,186,636 | 0.0% | 0.77% | -6.5% | |
| RCKT | ROCKET PHARMACEUTICALS INC | $33,419 | -27.3% | 2,107,149 | 0.0% | 0.73% | -10.1% | |
| CNTA | CENTESSA PHARMACEUTICALS PLCsponsored ads | $32,087 | -20.3% | 3,577,094 | 0.0% | 0.70% | -1.4% | |
| GH | New | GUARDANT HEALTH INC | $31,555 | – | 476,380 | +100.0% | 0.69% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $31,339 | – | 1,817,808 | +100.0% | 0.68% | – |
| CCXI | New | CHEMOCENTRYX INC | $28,980 | – | 1,155,964 | +100.0% | 0.63% | – |
| KALV | KALVISTA PHARMACEUTICALS INC | $28,453 | +11.4% | 1,930,322 | 0.0% | 0.62% | +38.0% | |
| LIANBIOsponsored ads | $28,400 | -39.8% | 7,655,015 | 0.0% | 0.62% | -25.4% | ||
| DYN | DYNE THERAPEUTICS INC | $27,041 | -18.9% | 2,805,045 | 0.0% | 0.59% | +0.3% | |
| VRNA | VERONA PHARMA PLCsponsored ads | $25,449 | -25.7% | 5,100,000 | 0.0% | 0.56% | -8.1% | |
| EWTX | EDGEWISE THERAPEUTICS INC | $25,352 | -36.5% | 2,613,623 | 0.0% | 0.55% | -21.4% | |
| STSA | SATSUMA PHARMACEUTICALS INC | $22,474 | -15.6% | 5,914,252 | 0.0% | 0.49% | +4.5% | |
| CNTB | CONNECT BIOPHARMA HLDGS LTDads | $21,113 | -41.4% | 6,991,003 | 0.0% | 0.46% | -27.4% | |
| HOWL | WEREWOLF THERAPEUTICS INC | $18,884 | -63.1% | 4,291,881 | 0.0% | 0.41% | -54.3% | |
| ETNB | 89BIO INC | $18,721 | -71.2% | 4,965,769 | 0.0% | 0.41% | -64.3% | |
| TANGO THERAPEUTICS INC | $17,055 | -30.7% | 2,250,000 | 0.0% | 0.37% | -14.3% | ||
| RLAY | RELAY THERAPEUTICS INC | $16,433 | -2.5% | 549,055 | 0.0% | 0.36% | +20.9% | |
| KDNY | CHINOOK THERAPEUTICS INC | $16,360 | +0.3% | 1,000,000 | 0.0% | 0.36% | +24.0% | |
| SYBX | SYNLOGIC INC | $16,000 | -0.8% | 6,666,666 | 0.0% | 0.35% | +22.9% | |
| WVE | WAVE LIFE SCIENCES LTD | $15,550 | -36.3% | 7,775,207 | 0.0% | 0.34% | -21.2% | |
| SCPH | Sell | SCPHARMACEUTICALS INC | $15,101 | +11.8% | 2,658,583 | -1.2% | 0.33% | +38.2% |
| KALA | KALA PHARMACEUTICALS INC | $15,007 | +14.1% | 10,874,613 | 0.0% | 0.33% | +40.9% | |
| SLDB | SOLID BIOSCIENCES INC | $14,841 | -31.4% | 12,367,873 | 0.0% | 0.32% | -15.2% | |
| ACHL | ACHILLES THERAPEUTICS PLCsponsored ads | $14,743 | -41.3% | 5,014,687 | 0.0% | 0.32% | -27.3% | |
| DA32 LIFE SCNCE TEC ACQSTN C | $14,573 | -1.0% | 1,500,000 | 0.0% | 0.32% | +22.8% | ||
| MIST | MILESTONE PHARMACEUTICALS IN | $14,423 | -2.0% | 2,246,503 | 0.0% | 0.32% | +21.6% | |
| XILIO THERAPEUTICS INC | $14,156 | -55.8% | 2,002,217 | 0.0% | 0.31% | -45.3% | ||
| GRPH | GRAPHITE BIO INC | $13,762 | -59.0% | 2,698,369 | 0.0% | 0.30% | -49.2% | |
| OTIC | OTONOMY INC | $13,440 | +15.4% | 5,600,000 | 0.0% | 0.29% | +42.9% | |
| CYT | CYTEIR THERAPEUTICS INC | $12,631 | -66.8% | 3,350,506 | 0.0% | 0.28% | -58.9% | |
| BLSA | BCLS ACQUISITION CORP | $12,338 | +0.7% | 1,250,000 | 0.0% | 0.27% | +24.5% | |
| IPSC | CENTURY THERAPEUTICS INC | $11,508 | -20.6% | 914,094 | 0.0% | 0.25% | -2.0% | |
| MORF | New | MORPHIC HLDG INC | $11,197 | – | 278,874 | +100.0% | 0.24% | – |
| AKUS | AKOUOS INC | $10,836 | -44.1% | 2,281,249 | 0.0% | 0.24% | -31.0% | |
| CNCE | CONCERT PHARMACEUTICALS INC | $10,223 | +7.0% | 3,033,603 | 0.0% | 0.22% | +32.7% | |
| FLACU | FRAZIER LIFESCIENCES ACQU CO | $9,990 | +0.7% | 1,000,000 | 0.0% | 0.22% | +24.6% | |
| IO BIOTECH INC | $9,846 | -17.2% | 1,857,755 | 0.0% | 0.22% | +2.4% | ||
| ARYA SCIENCES ACQUISITN | $9,710 | +0.1% | 1,000,000 | 0.0% | 0.21% | +24.0% | ||
| ALVR | New | ALLOVIR INC | $9,724 | – | 1,440,525 | +100.0% | 0.21% | – |
| PYXIS ONCOLOGY INC | $9,220 | -63.2% | 2,282,173 | 0.0% | 0.20% | -54.4% | ||
| ASTRIA THERAPEUTICS INC | $8,469 | +24.5% | 1,262,193 | 0.0% | 0.18% | +54.2% | ||
| FVAM | 5 01 ACQUISITION CORP | $7,388 | 0.0% | 750,000 | 0.0% | 0.16% | +23.8% | |
| BDTX | BLACK DIAMOND THERAPEUTICS I | $7,174 | -48.0% | 2,589,904 | 0.0% | 0.16% | -35.4% | |
| VERV | VERVE THERAPEUTICS INC | $7,081 | -38.1% | 310,284 | 0.0% | 0.16% | -23.3% | |
| ORTX | ORCHARD THERAPEUTICS PLCads | $6,903 | -46.1% | 9,694,789 | 0.0% | 0.15% | -33.2% | |
| ENTX | ENTERA BIO LTD | $6,753 | +1.9% | 2,353,000 | 0.0% | 0.15% | +25.6% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $6,194 | -1.7% | 625,000 | 0.0% | 0.14% | +21.6% | |
| LRMR | Sell | LARIMAR THERAPEUTICS INC | $5,192 | -63.9% | 1,281,860 | -4.0% | 0.11% | -55.5% |
| CUE HEALTH INC | $4,838 | -51.9% | 750,000 | 0.0% | 0.11% | -40.1% | ||
| PHAS | PHASEBIO PHARMACEUTICALS INC | $3,762 | -49.4% | 2,850,000 | 0.0% | 0.08% | -37.4% | |
| CGEM | CULLINAN ONCOLOGY INC | $3,665 | -32.1% | 350,000 | 0.0% | 0.08% | -15.8% | |
| Sell | TSCAN THERAPEUTICS INC | $2,861 | -49.4% | 1,021,764 | -18.6% | 0.06% | -38.0% | |
| BMEA | BIOMEA FUSION INC | $2,230 | -40.1% | 500,000 | 0.0% | 0.05% | -25.8% | |
| OLMA | Sell | OLEMA PHARMACEUTICALS INC | $2,149 | -89.3% | 504,505 | -76.5% | 0.05% | -86.8% |
| CVRX | CVRX INC | $1,647 | -51.0% | 275,000 | 0.0% | 0.04% | -39.0% | |
| CMPX | Sell | COMPASS THERAPEUTICS INC | $730 | -87.5% | 532,958 | -71.2% | 0.02% | -84.5% |
| SYRS | Exit | SYROS PHARMACEUTICALS INC | $0 | – | -900,000 | -100.0% | -0.05% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -1,025,641 | -100.0% | -0.16% | – |
| IKNA | Exit | IKENA ONCOLOGY INC | $0 | – | -750,000 | -100.0% | -0.17% | – |
| SBTX | Exit | SILVERBACK THERAPEUTICS INC | $0 | – | -1,742,186 | -100.0% | -0.20% | – |
| BOLT | Exit | BOLT BIOTHERAPEUTICS INC | $0 | – | -2,378,325 | -100.0% | -0.20% | – |
| NAUT | Exit | NAUTILUS | $0 | – | -2,436,430 | -100.0% | -0.22% | – |
| Exit | ADAGIO THERAPEUTICS INC | $0 | – | -4,995,807 | -100.0% | -0.64% | – | |
| TGTX | Exit | TG THERAPEUTICS INC | $0 | – | -2,210,145 | -100.0% | -0.74% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -1,377,569 | -100.0% | -0.78% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -3,333,700 | -100.0% | -0.96% | – |
| PHAT | Exit | PHATHOM PHARMACEUTICALS INC | $0 | – | -3,115,008 | -100.0% | -1.08% | – |
These EDGAR filings were analyzed to create this holdings report:
The EDGAR filing(s) were signed by:
- Rajeev Shah — Authorized Signatory
- RA Capital Management holdings (13F-HR)
- RA Capital Management significant holdings (13D/G)
- RA Capital Management ownership history
- RA Capital Management portfolio value
- RA Capital Management insiders transactions
- RA Capital Management filings
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