RA Capital Management Q4 2021 holdings

$5.67 Billion is the total value of RA Capital Management's 97 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 21.1% .

 Value Shares↓ Weighting
ASND BuyASCENDIS PHARMA A/Ssponsored$1,018,110
-13.5%
7,567,900
+2.4%
17.95%
+10.0%
NVAX  NOVAVAX INC$300,131
-31.0%
2,097,7940.0%5.29%
-12.2%
ITOS  ITEOS THERAPEUTICS INC$205,668
+72.4%
4,417,2590.0%3.63%
+119.4%
TVTX  TRAVERE THERAPEUTICS INC$174,272
+28.0%
5,614,4280.0%3.07%
+62.9%
JANX  JANUX THERAPEUTICS INC$171,072
-8.8%
8,670,6440.0%3.02%
+16.0%
 CYTEK BIOSCIENCES INC$156,787
-23.8%
9,607,0280.0%2.76%
-3.0%
IMGN BuyIMMUNOGEN INC$150,192
+43.8%
20,241,458
+9.9%
2.65%
+83.0%
 ELIEM THERAPEUTICS INC$137,558
-41.8%
13,150,8490.0%2.42%
-26.0%
 ICOSAVAX INC$132,231
-22.7%
5,779,3470.0%2.33%
-1.6%
 DICE THERAPEUTICS INC$131,838
-22.7%
5,208,9110.0%2.32%
-1.7%
VOR  VOR BIOPHARMA INC$129,226
-25.9%
11,120,9730.0%2.28%
-5.7%
FMTX  FORMA THERAPEUTICS$128,146
-38.7%
9,011,6510.0%2.26%
-22.0%
 TYRA BIOSCIENCES INC$101,817
-20.0%
7,236,4540.0%1.80%
+1.8%
PCVX BuyVAXCYTE INC$100,881
+2.0%
4,240,464
+8.8%
1.78%
+29.9%
MGNX BuyMACROGENICS INC$97,963
-21.3%
6,103,594
+2.7%
1.73%
+0.1%
AVTE  AEROVATE THERAPEUTICS INC$97,432
-43.8%
8,263,9820.0%1.72%
-28.5%
NKTX  NKARTA INC$86,039
-44.8%
5,605,1290.0%1.52%
-29.8%
DAWN  DAY ONE BIOPHARMACEUTICALS$83,670
-29.0%
4,965,5880.0%1.48%
-9.7%
TIL  INSTIL BIO INC$83,339
-4.3%
4,870,7930.0%1.47%
+21.8%
BLU NewBELLUS HEALTH INC NEW$82,35410,230,274
+100.0%
1.45%
CLDX BuyCELLDEX THERAPEUTICS INC NEW$69,737
-19.3%
1,804,795
+12.8%
1.23%
+2.8%
 TENAYA THERAPEUTICS INC$67,301
-8.2%
3,551,5080.0%1.19%
+16.8%
GHRS SellGH RESEARCH PLCordinary shares$66,345
-0.2%
2,843,757
-5.6%
1.17%
+27.0%
ABOS  ACUMEN PHARMACEUTICALS INC$66,050
-54.5%
9,770,7730.0%1.16%
-42.1%
ETNB  89BIO INC$64,903
-33.3%
4,965,7690.0%1.14%
-15.1%
KNTE  KINNATE BIOPHARMA INC$63,669
-23.0%
3,593,0520.0%1.12%
-2.0%
PHAT  PHATHOM PHARMACEUTICALS INC$61,272
-38.7%
3,115,0080.0%1.08%
-22.1%
MRTX NewMIRATI THERAPEUTICS INC$55,896381,046
+100.0%
0.98%
ZGNX  ZOGENIX INC$54,173
+7.0%
3,333,7000.0%0.96%
+36.0%
NewPARDES BIOSCIENCES INC$51,1903,127,038
+100.0%
0.90%
HOWL  WEREWOLF THERAPEUTICS INC$51,116
-30.6%
4,291,8810.0%0.90%
-11.8%
PNT BuyPOINT BIOPHARMA GLOBAL INC$50,417
-26.0%
9,003,018
+1.7%
0.89%
-5.8%
RYTM  RHYTHM PHARMACEUTICALS INC$48,613
-23.6%
4,871,0670.0%0.86%
-2.8%
NewLIANBIOsponsored ads$47,1557,655,015
+100.0%
0.83%
DSGN  DESIGN THERAPEUTICS INC$46,816
+45.7%
2,186,6360.0%0.82%
+85.4%
RCKT  ROCKET PHARMACEUTICALS INC$45,999
-27.0%
2,107,1490.0%0.81%
-7.1%
RLMD NewRELMADA THERAPEUTICS$45,0602,000,000
+100.0%
0.79%
CCCC  C4 THERAPEUTICS INC$44,358
-27.9%
1,377,5690.0%0.78%
-8.3%
TGTX SellTG THERAPEUTICS INC$41,993
-69.2%
2,210,145
-46.1%
0.74%
-60.8%
EYPT BuyEYEPOINT PHARMACEUTICALS$41,255
+79.1%
3,370,506
+52.5%
0.73%
+127.9%
CNTA  CENTESSA PHARMACEUTICALS PLCsponsored ads$40,278
-32.6%
3,577,0940.0%0.71%
-14.3%
EWTX  EDGEWISE THERAPEUTICS INC$39,936
-8.0%
2,613,6230.0%0.70%
+17.1%
PMVP  PMV PHARMACEUTICALS INC$39,507
-22.5%
1,710,2650.0%0.70%
-1.3%
CYT  CYTEIR THERAPEUTICS INC$38,095
-35.2%
3,350,5060.0%0.67%
-17.5%
GERN  GERON CORP$36,754
-10.9%
30,126,2990.0%0.65%
+13.3%
SellADAGIO THERAPEUTICS INC$36,270
-83.9%
4,995,807
-6.4%
0.64%
-79.6%
CNTB  CONNECT BIOPHARMA HLDGS LTDads$36,004
-78.7%
6,991,0030.0%0.64%
-72.9%
 RXSIGHT INC$34,344
-11.2%
3,052,7960.0%0.61%
+13.1%
VRNA  VERONA PHARMA PLCsponsored ads$34,272
+22.6%
5,100,0000.0%0.60%
+56.1%
GRPH  GRAPHITE BIO INC$33,541
-24.2%
2,698,3690.0%0.59%
-3.6%
DYN  DYNE THERAPEUTICS INC$33,352
-26.8%
2,805,0450.0%0.59%
-6.8%
NewXILIO THERAPEUTICS INC$32,0352,002,217
+100.0%
0.56%
STSA  SATSUMA PHARMACEUTICALS INC$26,614
-3.4%
5,914,2520.0%0.47%
+22.8%
KALV  KALVISTA PHARMACEUTICALS INC$25,538
-24.2%
1,930,3220.0%0.45%
-3.6%
ACHL  ACHILLES THERAPEUTICS PLCsponsored ads$25,124
-35.7%
5,014,6870.0%0.44%
-18.1%
NewPYXIS ONCOLOGY INC$25,0352,282,173
+100.0%
0.44%
 TANGO THERAPEUTICS INC$24,615
-15.4%
2,250,0000.0%0.43%
+7.7%
WVE  WAVE LIFE SCIENCES LTD$24,414
-35.9%
7,775,2070.0%0.43%
-18.6%
SLDB  SOLID BIOSCIENCES INC$21,644
-26.8%
12,367,8730.0%0.38%
-6.8%
OLMA  OLEMA PHARMACEUTICALS INC$20,128
-66.0%
2,150,4040.0%0.36%
-56.8%
AKUS  AKOUOS INC$19,391
-26.8%
2,281,2490.0%0.34%
-6.8%
RLAY NewRELAY THERAPEUTICS INC$16,861549,055
+100.0%
0.30%
KDNY NewCHINOOK THERAPEUTICS$16,3101,000,000
+100.0%
0.29%
SYBX  SYNLOGIC INC$16,133
-20.7%
6,666,6660.0%0.28%
+0.7%
 DA32 LIFE SCNCE$14,715
-0.2%
1,500,0000.0%0.26%
+27.0%
MIST  MILESTONE PHARMACEUTICALS IN$14,715
+14.7%
2,246,5030.0%0.26%
+45.5%
IPSC  CENTURY THERAPEUTICS INC$14,498
-37.0%
914,0940.0%0.26%
-19.7%
LRMR SellLARIMAR THERAPEUTICS INC$14,400
-17.6%
1,334,610
-11.9%
0.25%
+5.0%
BDTX  BLACK DIAMOND THERAPEUTICS INC$13,804
-37.0%
2,589,9040.0%0.24%
-20.1%
SCPH SellSCPHARMACEUTICALS$13,513
-25.6%
2,691,770
-1.4%
0.24%
-5.6%
KALA  KALA PHARMACEUTICALS INC$13,158
-53.8%
10,874,6130.0%0.23%
-41.3%
ORTX SellORCHARD THERAPEUTICS PLCads$12,797
-49.6%
9,694,789
-12.1%
0.23%
-35.6%
NAUT  NAUTILUS$12,621
-15.6%
2,436,4300.0%0.22%
+7.7%
BLSA  BCLS ACQUISITION CORP$12,250
-1.6%
1,250,0000.0%0.22%
+24.9%
NewIO BIOTECH INC$11,8901,857,755
+100.0%
0.21%
OTIC BuyOTONOMY INC$11,648
+271.8%
5,600,000
+243.2%
0.20%
+376.7%
SBTX  SILVERBACK THERAPEUTICS INC$11,603
-33.3%
1,742,1860.0%0.20%
-14.9%
BOLT  BOLT BIOTHERAPEUTICS INC$11,654
-61.3%
2,378,3250.0%0.20%
-50.8%
VERV SellVERVE THERAPEUTICS INC$11,440
-72.3%
310,284
-64.8%
0.20%
-64.7%
RNA  AVIDITY BIOSCIENCES INC$10,069
-3.5%
423,6160.0%0.18%
+22.8%
 CUE HEALTH INC$10,058
+13.5%
750,0000.0%0.18%
+43.9%
FLACU  FRAZIER LIFESCIENCES ACQU CO$9,920
+1.0%
1,000,0000.0%0.18%
+28.7%
 ARYA SCIENCES ACQUISITN$9,700
-1.8%
1,000,0000.0%0.17%
+24.8%
CNCE  CONCERT PHARMACEUTICALS INC$9,556
-3.7%
3,033,6030.0%0.17%
+22.6%
IKNA  IKENA ONCOLOGY INC$9,405
-0.6%
750,0000.0%0.17%
+26.7%
COGT  COGENT BIOSCIENCES INC$8,800
+2.0%
1,025,6410.0%0.16%
+29.2%
PHAS  PHASEBIO PHARMACEUTICALS INC$7,439
-16.1%
2,850,0000.0%0.13%
+6.5%
FVAM  5 01 ACQUISITION CORP$7,388
+0.3%
750,0000.0%0.13%
+27.5%
 ASTRIA THERAPEUTICS INC$6,803
-39.0%
1,262,1930.0%0.12%
-22.6%
ENTX  ENTERA BIO LTD$6,624
-40.2%
2,353,0000.0%0.12%
-24.0%
HSAQ  HEALTH SCIENCES ACQ CORP 2$6,300
+1.9%
625,0000.0%0.11%
+29.1%
CMPX NewCOMPASS THERAPEUTICS INC$5,8631,849,518
+100.0%
0.10%
 TSCAN THERAPEUTICS INC$5,649
-46.0%
1,255,3170.0%0.10%
-31.0%
CGEM  CULLINAN ONCOLOGY INC$5,401
-31.6%
350,0000.0%0.10%
-12.8%
BMEA  BIOMEA FUSION INC$3,725
-37.8%
500,0000.0%0.07%
-20.5%
CVRX  CVRX INC$3,363
-26.1%
275,0000.0%0.06%
-6.3%
SYRS  SYROS PHARMACEUTICALS INC$2,934
-27.1%
900,0000.0%0.05%
-7.1%
VRDN ExitVIRIDIAN THERAPEUTICS INC$0-1,034
-100.0%
0.00%
RPHM ExitRENEO PHARMACEUTICALS INC$0-62,217
-100.0%
-0.01%
CCXI ExitCHEMOCENTRYX INC$0-218,532
-100.0%
-0.05%
HLXA ExitHELIX ACQUISITION CORP$0-700,000
-100.0%
-0.10%
OCUL ExitOCULAR THERAPEUTIX INC$0-750,000
-100.0%
-0.10%
FSII ExitFS DEVELOPMENT CORP II$0-1,000,000
-100.0%
-0.14%
ExitAADI BIOSCIENCES INC$0-347,668
-100.0%
-0.14%
CTMX ExitCYTOMX THERAPEUTICS INC$0-3,500,000
-100.0%
-0.25%
AVIR ExitATEA PHARMACEUTICALS INC$0-5,427,655
-100.0%
-2.64%
Signed by
  • Rajeev Shah — Authorized Signatory

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