Baker Brothers Advisors Q3 2022 holdings

$15.3 Billion is the total value of Baker Brothers Advisors's 115 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 22.2% .

 Value Shares↓ Weighting
SGEN  Seagen Inc.$6,419,005
-22.7%
46,912,2660.0%42.04%
-10.7%
INCY BuyIncyte Corporation$2,409,341
-12.3%
36,154,574
+0.0%
15.78%
+1.3%
BGNE  BeiGene, Ltd.sponsored adr$1,573,201
-16.7%
11,668,8970.0%10.30%
-3.8%
ACAD  ACADIA Pharmaceuticals Inc.$685,868
+16.1%
41,923,4860.0%4.49%
+34.0%
BMRN  BioMarin Pharmaceutical Inc.$645,989
+2.3%
7,620,4940.0%4.23%
+18.1%
ASND  Ascendis Pharma A/Ssponsored adr$501,085
+11.1%
4,852,6550.0%3.28%
+28.3%
GBT  Global Blood Therapeutics, Inc.$254,183
+113.1%
3,732,5020.0%1.66%
+145.9%
BCRX  BioCryst Pharmaceuticals, Inc.$160,156
+19.1%
12,710,8180.0%1.05%
+37.5%
RYTM BuyRhythm Pharmaceuticals, Inc.$148,536
+767.7%
6,062,702
+47.0%
0.97%
+903.1%
KOD  Kodiak Sciences Inc.$133,983
+1.3%
17,310,4900.0%0.88%
+16.9%
IMCR BuyImmunocore Holdings plcads$118,323
+25.8%
2,520,731
+0.0%
0.78%
+45.1%
ABCL  AbCellera Biologics Inc.$103,352
-7.1%
10,450,1800.0%0.68%
+7.3%
ARGX Sellargenx SEsponsored adr$98,910
-76.7%
280,159
-75.0%
0.65%
-73.1%
MRTX  Mirati Therapeutics, Inc.$98,459
+4.0%
1,409,7840.0%0.64%
+20.1%
MDGL  Madrigal Pharmaceuticals, Inc.$97,434
-9.2%
1,499,2130.0%0.64%
+4.8%
CCXI  ChemoCentryx, Inc.$92,609
+108.5%
1,792,6570.0%0.61%
+140.5%
TVTX  Travere Therapeutics, Inc.$81,312
+1.7%
3,300,0090.0%0.53%
+17.4%
AKRO BuyAkero Therapeutics, Inc.$80,643
+7106.7%
2,368,378
+1900.7%
0.53%
+8700.0%
 Entrada Therapeutics, Inc.$76,685
+29.4%
4,865,8190.0%0.50%
+49.4%
IGMS  IGM Biosciences, Inc.$71,770
+26.1%
3,156,1020.0%0.47%
+45.5%
REPL BuyReplimune Group, Inc.$67,247
+7.1%
3,893,843
+8.4%
0.44%
+23.6%
PRLD  Prelude Therapeutics Inc.$66,918
+26.6%
10,123,8240.0%0.44%
+46.0%
KYMR  Kymera Therapeutics, Inc.$62,694
+10.6%
2,879,8250.0%0.41%
+27.6%
HZNP SellHorizon Therapeutics Public Ltd Co$60,016
-34.5%
969,727
-15.6%
0.39%
-24.4%
CERS  Cerus Corporation$57,843
-31.9%
16,067,5580.0%0.38%
-21.4%
NRIX  Nurix Therapeutics, Inc.$50,584
+2.8%
3,882,1250.0%0.33%
+18.6%
KDNY  Chinook Therapeutics, Inc.$49,820
+12.4%
2,534,1020.0%0.33%
+29.9%
VERV  Verve Therapeutics, Inc.$48,658
+124.8%
1,416,5300.0%0.32%
+159.3%
IMTX  Immatics N.V.$44,237
+14.8%
4,423,7310.0%0.29%
+32.4%
FMTX SellForma Therapeutics Holdings, Inc.$37,641
+169.8%
1,886,760
-6.8%
0.25%
+212.7%
 Insmed Incorporatednote 0.75% 6/1/2028$36,296
+9.1%
40,000,0000.0%0.24%
+25.9%
KNSA  Kiniksa Pharmaceuticals, Ltd.$35,947
+32.5%
2,799,5770.0%0.24%
+52.6%
HRTX  Heron Therapeutics, Inc.$34,316
+51.3%
8,131,6780.0%0.22%
+74.4%
AVTE SellAerovate Therapeutics, Inc.$32,821
+1.4%
1,979,568
-4.4%
0.22%
+16.8%
 2seventy bio, Inc.$30,013
+10.2%
2,062,7440.0%0.20%
+27.9%
KRYS SellKrystal Biotech, Inc.$29,426
-44.5%
422,185
-47.7%
0.19%
-35.9%
XENE  Xenon Pharmaceuticals Inc.$27,134
+18.7%
751,6390.0%0.18%
+36.9%
NewCinCor Pharma, Inc.$26,493807,212
+100.0%
0.17%
DBVT  DBV Technologies S.A.sponsored adr$25,867
-30.6%
14,614,2640.0%0.17%
-19.9%
IDYA NewIDEAYA Biosciences, Inc.$24,8921,668,355
+100.0%
0.16%
DSGN  Design Therapeutics, Inc.$24,021
+19.4%
1,436,6360.0%0.16%
+37.7%
VSTM  Verastem, Inc.$22,941
-26.7%
26,988,8980.0%0.15%
-15.7%
ALT SellAltimmune, Inc.$22,599
-6.9%
1,769,681
-14.7%
0.15%
+7.2%
BMEA  Biomea Fusion, Inc.$20,583
-18.4%
2,104,5590.0%0.14%
-5.6%
NVTA SellInvitae Corporation$20,669
-14.2%
8,402,035
-14.9%
0.14%
-1.5%
BCYC NewBicycle Therapeutics plcsponsored ads$19,627843,814
+100.0%
0.13%
RARE  Ultragenyx Pharmaceutical Inc.$19,503
-30.6%
470,9740.0%0.13%
-19.5%
TIL  Instil Bio, Inc.$18,846
+4.8%
3,893,7000.0%0.12%
+20.6%
VERU NewVeru Inc.$18,5421,609,579
+100.0%
0.12%
RLMD  Relmada Therapeutics, Inc.$18,329
+94.9%
495,1130.0%0.12%
+126.4%
ALKS SellAlkermes plc$18,199
-59.3%
815,016
-45.7%
0.12%
-53.1%
DNLI  Denali Therapeutics Inc.$18,068
+4.3%
588,7380.0%0.12%
+20.4%
OPT SellOpthea Limitedsponsored ads$16,687
-1.8%
2,691,391
-0.2%
0.11%
+13.5%
BLUE  bluebird bio, Inc.$15,823
+52.9%
2,499,7150.0%0.10%
+76.3%
CRNX SellCrinetics Pharmaceuticals, Inc.$14,449
-6.4%
735,716
-11.1%
0.10%
+8.0%
NewAadi Bioscience, Inc.$13,988989,928
+100.0%
0.09%
TCDA SellTricida, Inc.$13,837
-4.9%
1,320,290
-12.2%
0.09%
+9.6%
AFMD  Affimed N.V.$13,589
-25.6%
6,596,8300.0%0.09%
-14.4%
 DICE Therapeutics, Inc.$11,929
+30.7%
588,2350.0%0.08%
+50.0%
ANAB  AnaptysBio, Inc.$10,897
+25.7%
427,1790.0%0.07%
+44.9%
FGEN  FibroGen, Inc.$10,612
+23.2%
815,7180.0%0.07%
+40.8%
ZYME  Zymeworks Inc.$10,507
+16.0%
1,708,4720.0%0.07%
+35.3%
ADAP  Adaptimmune Therapeutics plcsponsored adr$10,568
-36.8%
9,830,8770.0%0.07%
-27.4%
PNT NewPOINT Biopharma Global Inc.$9,0371,169,103
+100.0%
0.06%
 TScan Therapeutics, Inc.$8,494
-3.0%
2,784,7920.0%0.06%
+12.0%
 Invitae Corporationnote 2.0% 9/1/2024$8,148
+0.8%
10,300,0000.0%0.05%
+15.2%
CBAY  CymaBay Therapeutics, Inc.$7,597
+18.6%
2,170,4640.0%0.05%
+38.9%
VERA  Vera Therapeutics, Inc.cl a$7,103
+56.6%
333,3330.0%0.05%
+80.8%
PACB SellPacific Biosciences of California, Inc.$6,547
-72.8%
1,127,782
-79.3%
0.04%
-68.6%
FLGT SellFulgent Genetics, Inc.$6,352
-42.2%
166,619
-17.3%
0.04%
-32.3%
AMRN SellAmarin Corporation plcsponsored adr$5,861
-81.4%
5,377,113
-74.6%
0.04%
-78.8%
ACHL  Achilles Therapeutics plcsponsored ads$5,856
-10.3%
2,591,3660.0%0.04%
+2.7%
VOR BuyVor Biopharma Inc.$5,834
+3.1%
1,465,925
+28.7%
0.04%
+18.8%
RETA  Reata Pharmaceuticals, Inc.cl a$5,629
-17.3%
223,9760.0%0.04%
-5.1%
BCEL  Atreca, Inc.$5,546
-12.3%
3,532,7600.0%0.04%0.0%
KRON NewKronos Bio, Inc.$5,1581,539,616
+100.0%
0.03%
NKTX  Nkarta, Inc.$5,264
+6.8%
400,0000.0%0.03%
+21.4%
TLIS  Talis Biomedical Corporation$5,197
-16.1%
7,624,8350.0%0.03%
-2.9%
CYT  Cyteir Therapeutics, Inc.$5,076
-35.8%
2,643,6400.0%0.03%
-26.7%
 Surrozen, Inc.$5,050
-32.7%
2,500,0000.0%0.03%
-23.3%
EWTX  Edgewise Therapeutics, Inc.$4,920
+23.6%
500,0000.0%0.03%
+39.1%
FATE NewFate Therapeutics, Inc.$4,834215,695
+100.0%
0.03%
STOK NewStoke Therapeutics, Inc.$4,742369,327
+100.0%
0.03%
NTRA  Natera, Inc.$4,382
+23.6%
100,0000.0%0.03%
+45.0%
RVMD  Revolution Medicines, Inc.$4,382
+1.2%
222,2220.0%0.03%
+16.0%
ALLK  Allakos Inc.$4,303
+95.5%
703,0500.0%0.03%
+133.3%
EIGR NewEiger BioPharmaceuticals, Inc.$4,065539,851
+100.0%
0.03%
PMVP NewPMV Pharmaceuticals, Inc.$3,832322,024
+100.0%
0.02%
IPSC NewCentury Therapeutics, Inc.$3,665370,587
+100.0%
0.02%
HOOK  HOOKIPA Pharma Inc.$3,217
-17.8%
2,400,4810.0%0.02%
-4.5%
ATHA  Athira Pharma, Inc.$3,091
-2.6%
1,040,8340.0%0.02%
+11.1%
MGNX  MacroGenics, Inc.$3,088
+17.3%
892,5790.0%0.02%
+33.3%
ITOS  iTeos Therapeutics, Inc.$2,864
-7.5%
150,3460.0%0.02%
+5.6%
ATRA  Atara Biotherapeutics, Inc.$2,813
-51.5%
744,1860.0%0.02%
-45.5%
 Tango Therapeutics, Inc.$2,715
-20.1%
750,0000.0%0.02%
-5.3%
SNDX  Syndax Pharmaceuticals, Inc.$2,661
+24.9%
110,7290.0%0.02%
+41.7%
OTIC BuyOtonomy, Inc.$2,491
-85.8%
8,443,134
+0.4%
0.02%
-83.8%
NLTX  Neoleukin Therapeutics, Inc.$2,446
-37.9%
3,821,7400.0%0.02%
-27.3%
ALGS  Aligos Therapeutics, Inc.$2,284
-9.1%
2,076,4000.0%0.02%
+7.1%
ALEC  Alector, Inc.$2,263
-6.9%
239,2280.0%0.02%
+7.1%
AGLE  Aeglea BioTherapeutics, Inc.$1,794
+4.2%
3,410,1060.0%0.01%
+20.0%
TCRR  TCR2 Therapeutics Inc.$1,356
-37.9%
753,0640.0%0.01%
-25.0%
LIFE SellaTyr Pharma, Inc.$604
-43.0%
201,361
-46.2%
0.00%
-33.3%
TARA  Protara Therapeutics, Inc.$591
+1.0%
199,6710.0%0.00%
+33.3%
FHTX  Foghorn Therapeutics Inc.$386
-36.9%
45,0270.0%0.00%0.0%
CABA  Cabaletta Bio, Inc.$430
-38.7%
662,0630.0%0.00%
-25.0%
INSM SellInsmed Incorporated$430
-99.0%
19,950
-99.1%
0.00%
-98.8%
LPTX  Leap Therapeutics, Inc.$493
-23.4%
559,7050.0%0.00%
-25.0%
KZR  Kezar Life Sciences, Inc.$533
+4.1%
61,9460.0%0.00%0.0%
GTH  Genetron Holdings Limitedads$356
-54.0%
455,3060.0%0.00%
-50.0%
 Sera Prognostics, Inc.$322
-2.7%
201,5620.0%0.00%0.0%
VINC  Vincerx Pharma, Inc.$333
+4.4%
241,3790.0%0.00%0.0%
 Bellicum Pharmaceuticals, Inc.$299
+1.0%
249,1230.0%0.00%0.0%
 Surrozen, Inc.w exp 8/11/2026$154
-3.1%
833,3330.0%0.00%0.0%
LOGC SellLogicBio Therapeutics, Inc.$38
-75.9%
139,105
-69.2%
0.00%
-100.0%
NEXI ExitNexImmune, Inc.$0-20,000
-100.0%
0.00%
PASG ExitPassage Bio, Inc.$0-117,161
-100.0%
-0.00%
BNR ExitBurning Rock Biotech Limitedsponsored ads$0-209,131
-100.0%
-0.00%
INZY ExitInozyme Pharma, Inc.$0-106,999
-100.0%
-0.00%
NGM ExitNGM Biopharmaceuticals, Inc.$0-55,294
-100.0%
-0.00%
EPZM ExitEpizyme, Inc.$0-1,000,000
-100.0%
-0.01%
BCAB ExitBioAtla, Inc.$0-825,000
-100.0%
-0.01%
ExitEvofem Biosciences, Inc.$0-2,583,616
-100.0%
-0.02%
CNTA ExitCentessa Pharmaceuticals plcsponsored ads$0-1,127,273
-100.0%
-0.03%
HRMY ExitHarmony Biosciences Holdings, Inc.$0-123,600
-100.0%
-0.03%
KRTX ExitKaruna Therapeutics, Inc.$0-69,966
-100.0%
-0.05%
MRUS ExitMerus N.V.$0-995,397
-100.0%
-0.13%
ExitSarepta Therapeutics, Inc.dbcv 1.5% 11/15/2024$0-29,174,000
-100.0%
-0.21%
LEGN ExitLegend Biotech Corporationsponsored ads$0-856,658
-100.0%
-0.27%

The following EDGAR filing(s) were analyzed to create this report:

The EDGAR filing(s) were signed by:

  • Alexandra Toohey — Chief Financial Officer

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