Baker Brothers Advisors Q2 2022 holdings

$17.6 Billion is the total value of Baker Brothers Advisors's 117 reported holdings in Q2 2022. The portfolio turnover from Q1 2022 to Q2 2022 was 9.3% .

 Value Shares↓ Weighting
SGEN  Seagen Inc.$8,300,656
+22.8%
46,912,2660.0%47.09%
+21.3%
INCY BuyIncyte Corporation$2,746,628
-4.3%
36,154,117
+0.0%
15.58%
-5.6%
BGNE  BeiGene, Ltd.sponsored adr$1,888,611
-14.2%
11,668,8970.0%10.71%
-15.3%
BMRN  BioMarin Pharmaceutical Inc.$631,510
+7.5%
7,620,4940.0%3.58%
+6.1%
ACAD BuyACADIA Pharmaceuticals Inc.$590,702
-41.8%
41,923,486
+0.0%
3.35%
-42.6%
ASND BuyAscendis Pharma A/Ssponsored adr$451,103
-15.4%
4,852,655
+6.8%
2.56%
-16.5%
ARGX  argenx SEsponsored adr$424,178
+20.2%
1,119,5570.0%2.41%
+18.6%
BCRX  BioCryst Pharmaceuticals, Inc.$134,480
-34.9%
12,710,8180.0%0.76%
-35.8%
KOD BuyKodiak Sciences Inc.$132,252
+7.5%
17,310,490
+8.7%
0.75%
+6.1%
GBT BuyGlobal Blood Therapeutics, Inc.$119,253
+3.9%
3,732,502
+12.6%
0.68%
+2.6%
ABCL  AbCellera Biologics Inc.$111,294
+9.2%
10,450,1800.0%0.63%
+7.9%
MDGL  Madrigal Pharmaceuticals, Inc.$107,314
-27.0%
1,499,2130.0%0.61%
-27.9%
MRTX  Mirati Therapeutics, Inc.$94,639
-18.4%
1,409,7840.0%0.54%
-19.4%
IMCR  Immunocore Holdings plcads$94,048
+24.8%
2,520,7300.0%0.53%
+23.3%
HZNP BuyHorizon Therapeutics Public Ltd Co$91,605
-3.1%
1,148,504
+27.8%
0.52%
-4.2%
CERS BuyCerus Corporation$84,997
+12.9%
16,067,558
+17.2%
0.48%
+11.3%
TVTX  Travere Therapeutics, Inc.$79,959
-6.0%
3,300,0090.0%0.45%
-7.2%
REPL BuyReplimune Group, Inc.$62,772
+129.4%
3,591,081
+122.8%
0.36%
+126.8%
BuyEntrada Therapeutics, Inc.$59,266
+34.2%
4,865,819
+3.4%
0.34%
+32.3%
IGMS  IGM Biosciences, Inc.$56,905
-32.5%
3,156,1020.0%0.32%
-33.4%
KYMR BuyKymera Therapeutics, Inc.$56,704
-43.8%
2,879,825
+20.8%
0.32%
-44.5%
KRYS  Krystal Biotech, Inc.$53,036
-1.3%
807,7350.0%0.30%
-2.6%
PRLD  Prelude Therapeutics Inc.$52,846
-24.3%
10,123,8240.0%0.30%
-25.2%
NRIX BuyNurix Therapeutics, Inc.$49,187
+43.1%
3,882,125
+58.2%
0.28%
+40.9%
LEGN SellLegend Biotech Corporationsponsored ads$47,116
-35.5%
856,658
-57.4%
0.27%
-36.3%
ALKS  Alkermes plc$44,685
+13.2%
1,500,0000.0%0.25%
+11.9%
CCXI BuyChemoCentryx, Inc.$44,422
+93.3%
1,792,657
+95.5%
0.25%
+90.9%
KDNY BuyChinook Therapeutics, Inc.$44,321
+16.1%
2,534,102
+8.6%
0.25%
+14.6%
INSM  Insmed Incorporated$42,516
-16.1%
2,156,0010.0%0.24%
-17.2%
IMTX  Immatics N.V.$38,531
+9.0%
4,423,7310.0%0.22%
+7.9%
DBVT  DBV Technologies S.A.sponsored adr$37,266
+60.4%
14,614,2640.0%0.21%
+57.5%
 Sarepta Therapeutics, Inc.dbcv 1.5% 11/15/2024$36,577
-4.6%
29,174,0000.0%0.21%
-5.5%
 Insmed Incorporatednote 0.75% 6/1/2028$33,278
-13.8%
40,000,0000.0%0.19%
-14.9%
AVTE  Aerovate Therapeutics, Inc.$32,354
-14.7%
2,070,0100.0%0.18%
-15.6%
AMRN  Amarin Corporation plcsponsored adr$31,543
-54.7%
21,169,8050.0%0.18%
-55.2%
VSTM  Verastem, Inc.$31,307
-17.7%
26,988,8980.0%0.18%
-18.7%
RARE BuyUltragenyx Pharmaceutical Inc.$28,098
-12.9%
470,974
+6.0%
0.16%
-14.1%
KNSA  Kiniksa Pharmaceuticals, Ltd.$27,128
-2.5%
2,799,5770.0%0.15%
-3.8%
 2seventy bio, Inc.$27,228
-22.6%
2,062,7440.0%0.15%
-23.8%
BMEA BuyBiomea Fusion, Inc.$25,213
+264.4%
2,104,559
+35.7%
0.14%
+257.5%
ALT BuyAltimmune, Inc.$24,282
+271.9%
2,075,403
+93.6%
0.14%
+263.2%
NVTA  Invitae Corporation$24,091
-69.4%
9,873,4880.0%0.14%
-69.7%
PACB  Pacific Biosciences of California, Inc.$24,067
-51.4%
5,444,9630.0%0.14%
-51.9%
XENE  Xenon Pharmaceuticals Inc.$22,865
-0.5%
751,6390.0%0.13%
-1.5%
HRTX  Heron Therapeutics, Inc.$22,687
-51.2%
8,131,6780.0%0.13%
-51.7%
MRUS SellMerus N.V.$22,536
-58.2%
995,397
-51.1%
0.13%
-58.7%
VERV  Verve Therapeutics, Inc.$21,645
-33.0%
1,416,5300.0%0.12%
-33.9%
DSGN  Design Therapeutics, Inc.$20,113
-13.3%
1,436,6360.0%0.11%
-14.3%
AFMD BuyAffimed N.V.$18,273
-18.9%
6,596,830
+28.0%
0.10%
-19.4%
TIL  Instil Bio, Inc.$17,989
-57.0%
3,893,7000.0%0.10%
-57.7%
OTIC BuyOtonomy, Inc.$17,498
-7.1%
8,412,634
+7.2%
0.10%
-8.3%
DNLI BuyDenali Therapeutics Inc.$17,327
+506.9%
588,738
+563.5%
0.10%
+512.5%
RYTM  Rhythm Pharmaceuticals, Inc.$17,119
-64.0%
4,125,0620.0%0.10%
-64.5%
OPT  Opthea Limitedsponsored ads$16,986
-8.1%
2,696,1910.0%0.10%
-9.4%
ADAP  Adaptimmune Therapeutics plcsponsored adr$16,712
-17.5%
9,830,8770.0%0.10%
-18.1%
CRNX  Crinetics Pharmaceuticals, Inc.$15,433
-15.0%
827,4800.0%0.09%
-15.4%
TCDA SellTricida, Inc.$14,550
+2.2%
1,503,090
-13.2%
0.08%
+1.2%
FMTX  Forma Therapeutics Holdings, Inc.$13,951
-25.9%
2,024,8760.0%0.08%
-26.9%
FLGT  Fulgent Genetics, Inc.$10,985
-12.6%
201,4440.0%0.06%
-13.9%
BLUE  bluebird bio, Inc.$10,349
-14.6%
2,499,7150.0%0.06%
-15.7%
RLMD  Relmada Therapeutics, Inc.$9,402
-29.6%
495,1130.0%0.05%
-31.2%
 DICE Therapeutics, Inc.$9,129
-18.9%
588,2350.0%0.05%
-20.0%
ZYME  Zymeworks Inc.$9,055
-19.1%
1,708,4720.0%0.05%
-20.3%
BuyTScan Therapeutics, Inc.$8,758
+119.5%
2,784,792
+95.4%
0.05%
+117.4%
KRTX  Karuna Therapeutics, Inc.$8,851
-0.2%
69,9660.0%0.05%
-2.0%
FGEN BuyFibroGen, Inc.$8,614
+23.2%
815,718
+40.2%
0.05%
+22.5%
ANAB  AnaptysBio, Inc.$8,672
-17.9%
427,1790.0%0.05%
-19.7%
 Invitae Corporationnote 2.0% 9/1/2024$8,087
-3.5%
10,300,0000.0%0.05%
-4.2%
CYT BuyCyteir Therapeutics, Inc.$7,904
+158.0%
2,643,640
+225.3%
0.04%
+150.0%
 Surrozen, Inc.$7,500
-0.3%
2,500,0000.0%0.04%0.0%
RETA  Reata Pharmaceuticals, Inc.cl a$6,807
-7.2%
223,9760.0%0.04%
-7.1%
ACHL  Achilles Therapeutics plcsponsored ads$6,530
-14.3%
2,591,3660.0%0.04%
-15.9%
CBAY  CymaBay Therapeutics, Inc.$6,403
-5.1%
2,170,4640.0%0.04%
-7.7%
BCEL  Atreca, Inc.$6,324
-43.5%
3,532,7600.0%0.04%
-43.8%
TLIS  Talis Biomedical Corporation$6,191
-42.4%
7,624,8350.0%0.04%
-43.5%
HRMY  Harmony Biosciences Holdings, Inc.$6,028
+0.2%
123,6000.0%0.03%
-2.9%
ATRA NewAtara Biotherapeutics, Inc.$5,797744,186
+100.0%
0.03%
VOR NewVor Biopharma Inc.$5,6601,138,768
+100.0%
0.03%
CNTA  Centessa Pharmaceuticals plcsponsored ads$5,490
-45.7%
1,127,2730.0%0.03%
-46.6%
NKTX NewNkarta, Inc.$4,928400,000
+100.0%
0.03%
VERA  Vera Therapeutics, Inc.cl a$4,537
-42.1%
333,3330.0%0.03%
-42.2%
RVMD  Revolution Medicines, Inc.$4,331
-23.6%
222,2220.0%0.02%
-24.2%
EWTX  Edgewise Therapeutics, Inc.$3,980
-17.9%
500,0000.0%0.02%
-17.9%
HOOK  HOOKIPA Pharma Inc.$3,913
-28.5%
2,400,4810.0%0.02%
-29.0%
NLTX  Neoleukin Therapeutics, Inc.$3,936
-45.2%
3,821,7400.0%0.02%
-46.3%
NTRA NewNatera, Inc.$3,544100,000
+100.0%
0.02%
 Tango Therapeutics, Inc.$3,398
-40.2%
750,0000.0%0.02%
-42.4%
ITOS  iTeos Therapeutics, Inc.$3,097
-36.0%
150,3460.0%0.02%
-35.7%
ATHA BuyAthira Pharma, Inc.$3,175
-70.8%
1,040,834
+29.1%
0.02%
-71.4%
NewEvofem Biosciences, Inc.$2,9192,583,616
+100.0%
0.02%
MGNX BuyMacroGenics, Inc.$2,633
-32.5%
892,579
+101.7%
0.02%
-31.8%
ALEC  Alector, Inc.$2,431
-28.7%
239,2280.0%0.01%
-30.0%
ALGS  Aligos Therapeutics, Inc.$2,512
-43.7%
2,076,4000.0%0.01%
-46.2%
BCAB  BioAtla, Inc.$2,351
-43.0%
825,0000.0%0.01%
-45.8%
ALLK  Allakos Inc.$2,201
-45.1%
703,0500.0%0.01%
-47.8%
TCRR  TCR2 Therapeutics Inc.$2,184
+5.1%
753,0640.0%0.01%0.0%
SNDX  Syndax Pharmaceuticals, Inc.$2,130
+10.7%
110,7290.0%0.01%
+9.1%
AGLE  Aeglea BioTherapeutics, Inc.$1,722
-78.0%
3,410,1060.0%0.01%
-77.8%
EPZM  Epizyme, Inc.$1,470
+27.8%
1,000,0000.0%0.01%
+14.3%
AKRO  Akero Therapeutics, Inc.$1,119
-33.4%
118,3780.0%0.01%
-40.0%
LIFE SellaTyr Pharma, Inc.$1,060
-68.3%
374,395
-40.1%
0.01%
-68.4%
CABA  Cabaletta Bio, Inc.$702
-47.8%
662,0630.0%0.00%
-50.0%
LPTX  Leap Therapeutics, Inc.$644
-34.2%
559,7050.0%0.00%
-33.3%
GTH  Genetron Holdings Limitedads$774
-22.4%
455,3060.0%0.00%
-33.3%
NGM SellNGM Biopharmaceuticals, Inc.$709
-84.1%
55,294
-81.1%
0.00%
-84.6%
TARA  Protara Therapeutics, Inc.$585
-42.6%
199,6710.0%0.00%
-50.0%
KZR SellKezar Life Sciences, Inc.$512
-77.9%
61,946
-55.7%
0.00%
-76.9%
INZY  Inozyme Pharma, Inc.$510
+16.4%
106,9990.0%0.00%0.0%
FHTX  Foghorn Therapeutics Inc.$612
-10.8%
45,0270.0%0.00%
-25.0%
BNR  Burning Rock Biotech Limitedsponsored ads$609
-68.7%
209,1310.0%0.00%
-72.7%
VINC  Vincerx Pharma, Inc.$319
-67.0%
241,3790.0%0.00%
-66.7%
 Bellicum Pharmaceuticals, Inc.$296
-45.0%
249,1230.0%0.00%
-33.3%
 Sera Prognostics, Inc.$331
-56.7%
201,5620.0%0.00%
-50.0%
PASG  Passage Bio, Inc.$276
-24.0%
117,1610.0%0.00%0.0%
LOGC  LogicBio Therapeutics, Inc.$158
-48.5%
451,4780.0%0.00%
-50.0%
 Surrozen, Inc.w exp 8/11/2026$159
-23.6%
833,3330.0%0.00%0.0%
NEXI SellNexImmune, Inc.$32
-97.4%
20,000
-93.2%
0.00%
-100.0%
OYST ExitOyster Point Pharma, Inc.$0-61,424
-100.0%
-0.00%
NVAX ExitNovavax, Inc.$0-48,168
-100.0%
-0.02%
KURA ExitKura Oncology, Inc.$0-274,458
-100.0%
-0.02%
SRPT ExitSarepta Therapeutics, Inc.$0-123,456
-100.0%
-0.06%
AXSM ExitAxsome Therapeutics, Inc.$0-610,970
-100.0%
-0.14%
NBIX ExitNeurocrine Biosciences, Inc.$0-676,975
-100.0%
-0.36%

The following EDGAR filing(s) were analyzed to create this report:

The EDGAR filing(s) were signed by:

  • Alexandra Toohey — Chief Financial Officer

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EDGAR filings