$3.56 Billion is the total value of Perceptive Advisors's 96 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 43.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | Buy | AMICUS THERAPEUTICS INC | $337,520,017 | +18.1% | 27,642,917 | +1.0% | 9.48% | +14.3% |
| Buy | AMYLYX PHARMACEUTICALS INC | $224,963,904 | +46.0% | 6,088,333 | +11.3% | 6.32% | +41.3% | |
| MDGL | Buy | MADRIGAL PHARMACEUTICALS INC | $212,443,263 | +887.5% | 731,932 | +121.1% | 5.97% | +856.1% |
| CERE | CEREVEL THERAPEUTICS HLDNG I | $205,379,869 | +11.6% | 6,511,727 | 0.0% | 5.77% | +8.0% | |
| RXDX | Sell | PROMETHEUS BIOSCIENCES INC | $133,396,340 | +53.9% | 1,212,694 | -17.4% | 3.75% | +48.9% |
| VRNA | Sell | VERONA PHARMA PLCsponsored ads | $127,533,187 | +147.2% | 4,880,719 | -3.3% | 3.58% | +139.2% |
| HZNP | New | HORIZON THERAPEUTICS PUB L | $109,248,000 | – | 960,000 | +100.0% | 3.07% | – |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $99,293,467 | -48.9% | 2,191,425 | -21.3% | 2.79% | -50.6% |
| LIANBIOsponsored ads | $94,395,859 | -18.0% | 57,558,451 | 0.0% | 2.65% | -20.7% | ||
| MDGL | New | MADRIGAL PHARMACEUTICALS INCput | $87,075,000 | – | 300,000 | +100.0% | 2.44% | – |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $84,129,815 | +200.8% | 649,250 | +156.6% | 2.36% | +190.9% |
| INBX | Buy | INHIBRX INC | $81,651,613 | +57.5% | 3,313,783 | +14.7% | 2.29% | +52.5% |
| Buy | ARCELLX INC | $80,495,489 | +73.9% | 2,598,305 | +5.4% | 2.26% | +68.3% | |
| ALDX | ALDEYRA THERAPEUTICS INC | $78,996,592 | +30.3% | 11,350,085 | 0.0% | 2.22% | +26.1% | |
| XENE | Sell | XENON PHARMACEUTICALS INC | $75,755,794 | -1.1% | 1,921,273 | -9.5% | 2.13% | -4.4% |
| CRNX | Sell | CRINETICS PHARMACEUTICALS IN | $73,918,751 | -29.3% | 4,039,276 | -24.1% | 2.08% | -31.6% |
| BLU | Sell | BELLUS HEALTH INC NEW | $73,084,242 | -32.5% | 8,891,027 | -13.2% | 2.05% | -34.6% |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS INC | $68,086,143 | -31.2% | 2,617,691 | -24.6% | 1.91% | -33.5% |
| Buy | NUVALENT INC | $67,154,108 | +108.7% | 2,255,007 | +36.3% | 1.89% | +101.9% | |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $63,719,674 | -35.1% | 9,971,780 | -2.7% | 1.79% | -37.2% |
| PCVX | New | VAXCYTE INC | $56,101,500 | – | 1,170,000 | +100.0% | 1.58% | – |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $52,415,719 | +83.8% | 506,481 | +50.5% | 1.47% | +77.8% |
| ADMA | Buy | ADMA BIOLOGICS INC | $46,172,989 | +73.8% | 11,900,255 | +8.8% | 1.30% | +68.2% |
| MGTX | MEIRAGTX HLDGS PLC | $45,375,686 | -22.5% | 6,963,277 | 0.0% | 1.27% | -25.1% | |
| TMCI | Buy | TREACE MEDICAL CONCEPTS INC | $44,747,805 | +26.6% | 1,946,403 | +21.5% | 1.26% | +22.5% |
| VERU | Buy | VERU INC | $41,490,298 | -7.5% | 7,858,011 | +101.8% | 1.16% | -10.5% |
| ALBO | Sell | ALBIREO PHARMA INC | $37,972,228 | -16.9% | 1,757,160 | -25.5% | 1.07% | -19.6% |
| COGT | COGENT BIOSCIENCES INC | $37,078,018 | -22.5% | 3,207,441 | 0.0% | 1.04% | -25.1% | |
| VRDN | VIRIDIAN THERAPEUTICS INC | $35,652,996 | +42.4% | 1,220,575 | 0.0% | 1.00% | +37.7% | |
| RAPT | Buy | RAPT THERAPEUTICS INC | $35,619,309 | -13.6% | 1,798,955 | +5.0% | 1.00% | -16.4% |
| New | ZYMEWORKS DEL INC | $35,458,621 | – | 4,511,275 | +100.0% | 1.00% | – | |
| New | ACRIVON THERAPEUTICS INC | $34,650,524 | – | 3,007,858 | +100.0% | 0.97% | – | |
| ESTA | Sell | ESTABLISHMENT LABS HLDGS INC | $32,684,312 | +3.5% | 497,857 | -13.9% | 0.92% | +0.2% |
| Buy | ASTRIA THERAPEUTICS INC | $32,601,089 | +181.5% | 2,189,462 | +70.9% | 0.92% | +172.3% | |
| Sell | CINCOR PHARMA INC | $31,663,034 | -70.8% | 2,576,325 | -22.1% | 0.89% | -71.8% | |
| IMTX | Buy | IMMATICS N.V | $30,410,965 | +21.6% | 3,491,500 | +39.7% | 0.85% | +17.6% |
| RLAY | RELAY THERAPEUTICS INC | $29,029,869 | -33.2% | 1,943,097 | 0.0% | 0.82% | -35.4% | |
| LYRA | LYRA THERAPEUTICS INC | $28,720,732 | -37.3% | 9,146,730 | 0.0% | 0.81% | -39.4% | |
| OM | Sell | OUTSET MED INC | $28,129,005 | +51.1% | 1,089,427 | -6.8% | 0.79% | +46.3% |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | $22,690,400 | +24.4% | 411,804 | 0.0% | 0.64% | +20.4% | |
| RCKT | Buy | ROCKET PHARMACEUTICALS INC | $21,100,452 | +164.4% | 1,078,204 | +115.6% | 0.59% | +155.6% |
| VBIV | VBI VACCINES INC CDA | $20,410,650 | -45.1% | 52,335,002 | 0.0% | 0.57% | -46.8% | |
| RAIN | RAIN ONCOLOGY INC | $19,868,952 | +63.9% | 2,483,619 | 0.0% | 0.56% | +58.5% | |
| AKRO | Sell | AKERO THERAPEUTICS INC | $19,208,770 | +31.2% | 350,525 | -18.5% | 0.54% | +26.8% |
| TARS | TARSUS PHARMACEUTICALS INC | $19,005,459 | -14.4% | 1,296,416 | 0.0% | 0.53% | -17.1% | |
| New | SOLID BIOSCIENCES INC | $18,808,120 | – | 3,495,933 | +100.0% | 0.53% | – | |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | $16,400,071 | -15.1% | 9,111,151 | 0.0% | 0.46% | -17.8% | |
| New | ROIVANT SCIENCES LTD | $15,832,744 | – | 1,981,570 | +100.0% | 0.44% | – | |
| ATHA | ATHIRA PHARMA INC | $15,207,371 | +6.7% | 4,797,278 | 0.0% | 0.43% | +3.1% | |
| PRTA | Buy | PROTHENA CORP PLC | $14,318,172 | +2.7% | 237,646 | +3.3% | 0.40% | -0.7% |
| AXGN | Buy | AXOGEN INC | $13,853,497 | +22.4% | 1,388,126 | +46.2% | 0.39% | +18.2% |
| VRCA | VERRICA PHARMACEUTICALS INC | $13,857,203 | -5.8% | 5,038,983 | 0.0% | 0.39% | -8.9% | |
| RVNC | Sell | REVANCE THERAPEUTICS INC | $13,459,131 | -38.4% | 729,097 | -9.8% | 0.38% | -40.4% |
| CYTEK BIOSCIENCES INC | $13,166,142 | -30.6% | 1,289,534 | 0.0% | 0.37% | -32.8% | ||
| CRY | Sell | ARTIVION INC | $13,160,623 | -21.0% | 1,085,860 | -9.8% | 0.37% | -23.6% |
| BBIO | BRIDGEBIO PHARMA INC | $12,931,391 | -23.3% | 1,697,033 | 0.0% | 0.36% | -25.9% | |
| ISEE | Sell | IVERIC BIO INC | $12,576,234 | -32.2% | 587,400 | -43.2% | 0.35% | -34.4% |
| NBIX | NEUROCRINE BIOSCIENCES INC | $11,949,972 | +12.5% | 100,050 | 0.0% | 0.34% | +9.1% | |
| LRMR | LARIMAR THERAPEUTICS INC | $11,811,800 | +29.1% | 2,860,000 | 0.0% | 0.33% | +24.8% | |
| CMAX | Sell | CAREMAX INC | $11,421,562 | -52.5% | 3,129,195 | -7.8% | 0.32% | -54.1% |
| ISRG | New | INTUITIVE SURGICAL INC | $10,614,000 | – | 40,000 | +100.0% | 0.30% | – |
| MORF | MORPHIC HLDG INC | $9,715,520 | -5.5% | 363,197 | 0.0% | 0.27% | -8.4% | |
| Sell | DICE THERAPEUTICS INC | $9,152,894 | -34.3% | 293,362 | -57.3% | 0.26% | -36.5% | |
| LABP | LANDOS BIOPHARMA INC | $7,434,957 | -23.1% | 14,869,915 | 0.0% | 0.21% | -25.4% | |
| SCPH | New | SCPHARMACEUTICALS INC | $6,828,565 | – | 952,380 | +100.0% | 0.19% | – |
| Sell | HILLEVAX INC | $6,792,782 | -48.0% | 406,024 | -46.9% | 0.19% | -49.6% | |
| OMIC | Sell | SINGULAR GENOMICS SYSTEMS IN | $6,597,373 | -25.4% | 3,282,275 | -7.2% | 0.18% | -28.0% |
| ISOPLEXIS CORP | $6,348,021 | -9.9% | 4,095,498 | 0.0% | 0.18% | -12.7% | ||
| PEN | New | PENUMBRA INC | $5,650,484 | – | 25,400 | +100.0% | 0.16% | – |
| ACRS | ACLARIS THERAPEUTICS INC | $5,374,514 | +0.1% | 341,239 | 0.0% | 0.15% | -3.2% | |
| NTRA | Buy | NATERA INC | $5,222,100 | -0.7% | 130,000 | +8.3% | 0.15% | -3.9% |
| CBAY | New | CYMABAY THERAPEUTICS INC | $4,445,386 | – | 708,993 | +100.0% | 0.12% | – |
| SAVA | New | CASSAVA SCIENCES INCput | $4,431,000 | – | 150,000 | +100.0% | 0.12% | – |
| ENVVENO MEDICAL CORPORATION | $3,986,236 | -18.8% | 781,615 | 0.0% | 0.11% | -21.1% | ||
| NBTX | NANOBIOTIXsponsored ads | $3,889,466 | +3.7% | 1,059,800 | 0.0% | 0.11% | 0.0% | |
| TYRA BIOSCIENCES INC | $3,757,463 | -13.5% | 494,403 | 0.0% | 0.11% | -15.9% | ||
| SOMALOGIC INC | $3,765,000 | -13.4% | 1,500,000 | 0.0% | 0.11% | -15.9% | ||
| PNT | POINT BIOPHARMA GLOBAL INC | $3,645,000 | -5.7% | 500,000 | 0.0% | 0.10% | -8.9% | |
| LPTX | Sell | LEAP THERAPEUTICS INC | $3,026,923 | -54.0% | 6,726,496 | -10.0% | 0.08% | -55.5% |
| CABA | New | CABALETTA BIO INC | $2,936,450 | – | 317,454 | +100.0% | 0.08% | – |
| KRON | Sell | KRONOS BIO INC | $2,839,446 | -60.7% | 1,752,745 | -18.7% | 0.08% | -61.9% |
| IMVT | New | IMMUNOVANT INC | $2,662,500 | – | 150,000 | +100.0% | 0.08% | – |
| Sell | PROCEPT BIOROBOTICS CORP | $2,680,867 | -75.5% | 64,537 | -75.5% | 0.08% | -76.3% | |
| ATNX | ATHENEX INC | $2,291,039 | -45.2% | 15,532,467 | 0.0% | 0.06% | -47.1% | |
| PRVA | New | PRIVIA HEALTH GROUP INC | $2,043,900 | – | 90,000 | +100.0% | 0.06% | – |
| TVTX | TRAVERE THERAPEUTICS INC | $1,908,430 | -14.6% | 90,748 | 0.0% | 0.05% | -16.9% | |
| ABOS | Sell | ACUMEN PHARMACEUTICALS INC | $1,876,230 | -53.2% | 347,450 | -13.1% | 0.05% | -54.3% |
| DARIOHEALTH CORP | $1,403,279 | -7.6% | 327,869 | 0.0% | 0.04% | -11.4% | ||
| CLOV | CLOVER HEALTH INVESTMENTS CO | $1,394,250 | -45.3% | 1,500,000 | 0.0% | 0.04% | -47.3% | |
| NVRO | Sell | NEVRO CORP | $1,188,000 | -83.0% | 30,000 | -80.0% | 0.03% | -83.7% |
| PEAR THERAPEUTICS INC | $1,062,646 | -42.2% | 900,548 | 0.0% | 0.03% | -43.4% | ||
| TARA | PROTARA THERAPEUTICS INC | $777,337 | -9.5% | 290,051 | 0.0% | 0.02% | -12.0% | |
| EQRX INC*w exp 12/17/202 | $67,050 | -67.3% | 250,000 | 0.0% | 0.00% | -66.7% | ||
| MOTUS GI HLDGS INC | $75,623 | -65.8% | 90,027 | 0.0% | 0.00% | -66.7% | ||
| CMAXW | CAREMAX INC*w exp 06/08/202 | $31,308 | -72.3% | 60,000 | 0.0% | 0.00% | -66.7% | |
| Exit | SURROZEN INC | $0 | – | -6,017 | -100.0% | 0.00% | – | |
| SURROZEN INC*w exp 08/01/203 | $9,183 | -70.4% | 166,666 | 0.0% | 0.00% | -100.0% | ||
| Exit | NEPTUNE WELLNESS SOLUTIONS I | $0 | – | -57,142 | -100.0% | -0.00% | – | |
| Exit | AGILE THERAPEUTICS INC | $0 | – | -532,361 | -100.0% | -0.01% | – | |
| Exit | ICOSAVAX INC | $0 | – | -93,591 | -100.0% | -0.01% | – | |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -110,728 | -100.0% | -0.01% | – |
| Exit | SONENDO INC | $0 | – | -612,204 | -100.0% | -0.02% | – | |
| Exit | HYPERFINE INC | $0 | – | -927,388 | -100.0% | -0.02% | – | |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -294,118 | -100.0% | -0.07% | – |
| Exit | SCIENCE 37 HOLDINGS INC | $0 | – | -1,500,000 | -100.0% | -0.07% | – | |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -16,200,818 | -100.0% | -0.07% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -100,000 | -100.0% | -0.07% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -750,000 | -100.0% | -0.08% | – |
| Exit | ABSCI CORPORATION | $0 | – | -894,346 | -100.0% | -0.08% | – | |
| Exit | PYXIS ONCOLOGY INC | $0 | – | -1,528,812 | -100.0% | -0.09% | – | |
| YMAB | Exit | Y-MABS THERAPEUTICS INC | $0 | – | -212,018 | -100.0% | -0.09% | – |
| Exit | COHERUS BIOSCIENCES INCnote 1.500% 4/1 | $0 | – | -4,500,000 | -100.0% | -0.10% | – | |
| HCAT | Exit | HEALTH CATALYST INC | $0 | – | -389,962 | -100.0% | -0.11% | – |
| CTIC | Exit | CTI BIOPHARMA CORP | $0 | – | -735,165 | -100.0% | -0.12% | – |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -5,000,000 | -100.0% | -0.13% | – | |
| NARI | Exit | INARI MED INC | $0 | – | -70,000 | -100.0% | -0.15% | – |
| TCDA | Exit | TRICIDA INCput | $0 | – | -500,000 | -100.0% | -0.15% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -310,500 | -100.0% | -0.18% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -13,412,552 | -100.0% | -0.18% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -766,231 | -100.0% | -0.20% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -192,680 | -100.0% | -0.29% | – |
| CNCE | Exit | CONCERT PHARMACEUTICALS INC | $0 | – | -2,150,641 | -100.0% | -0.42% | – |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -1,667,123 | -100.0% | -0.46% | – |
| RCUS | Exit | ARCUS BIOSCIENCES INC | $0 | – | -666,477 | -100.0% | -0.51% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -366,400 | -100.0% | -0.73% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -4,400,099 | -100.0% | -0.78% | – |
| EW | Exit | EDWARDS LIFESCIENCES CORP | $0 | – | -330,000 | -100.0% | -0.79% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -316,544 | -100.0% | -1.26% | – |
| Exit | TRAVERE THERAPEUTICS INCnote 2.250% 3/0 | $0 | – | -45,000,000 | -100.0% | -1.33% | – | |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -2,383,478 | -100.0% | -2.56% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -2,322,247 | -100.0% | -4.59% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
About Perceptive Advisors
Perceptive Advisors is a New York-based hedge fund that specializes in healthcare investments. The company was founded in 1999 by Joseph Edelman, who serves as the CEO and Chief Investment Officer. Since its inception, Perceptive Advisors has become one of the most successful healthcare-focused hedge funds in the world, with over $5 billion in assets under management.
The company's investment strategy is based on a deep understanding of the healthcare industry and a focus on identifying promising companies with innovative products and technologies. Perceptive Advisors invests in a wide range of healthcare sectors, including biotechnology, pharmaceuticals, medical devices, and healthcare services.
One of the key factors behind Perceptive Advisors' success is its team of experienced professionals. In addition to Joseph Edelman, the company's leadership team includes Adam Stone, the COO, and Jeremy Goldberg, the Chief Scientific Officer. The team also includes a group of highly skilled analysts and researchers who are experts in their respective fields.
Perceptive Advisors has a strong track record of generating high returns for its investors. However, it is important to note that investing in hedge funds carries significant risks, and investors should carefully consider their investment objectives and risk tolerance before investing. As with any investment, it is important to conduct thorough research and seek the advice of a qualified financial advisor before making any investment decisions.
It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES SHARES | 42 | Q3 2023 | 15.7% |
| AMICUS THERAPEUTICS SHARES | 39 | Q3 2023 | 14.0% |
| ALDEYRA THERAPEUTICS SHARES | 35 | Q3 2023 | 3.3% |
| QUOTIENT TECHNOLOGY INC | 34 | Q3 2022 | 2.7% |
| GLOBAL BLOOD THERAPEUTICS SHARES | 29 | Q3 2022 | 9.3% |
| ADMA BIOLOGICS SHARES | 29 | Q3 2023 | 1.4% |
| RETROPHIN SHARES | 28 | Q3 2020 | 5.5% |
| DBV TECHNOLOGIES SA-SPON ADR | 28 | Q3 2021 | 1.8% |
| VBI VACCINES SHARES | 27 | Q1 2023 | 2.8% |
| IOVANCE BIOTHERAPEUTICS INC | 26 | Q3 2023 | 9.1% |
View Perceptive Advisors's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| CHEMBIO DIAGNOSTICS, INC.Sold out | May 04, 2023 | 0 | 0.0% |
| VBI Vaccines Inc/BC | April 07, 2023 | 43,509,553 | 16.7% |
| Landos Biopharma, Inc. | March 30, 2023 | 14,869,915 | 47.7% |
| REATA PHARMACEUTICALS INC | March 07, 2023 | 2,083,799 | 6.5% |
| AGILE THERAPEUTICS INCSold out | February 14, 2023 | 0 | 0.0% |
| ALBIREO PHARMA, INC. | February 14, 2023 | 1,757,160 | 8.5% |
| BELLUS Health Inc. | February 14, 2023 | 8,891,027 | 7.1% |
| CinCor Pharma, Inc. | February 14, 2023 | 2,576,325 | 5.9% |
| Coherus BioSciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| CONCERT PHARMACEUTICALS, INC. | February 14, 2023 | 1,800,000 | 3.6% |
View Perceptive Advisors's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-04-17 |
| 4 | 2024-04-15 |
| SC 13G/A | 2024-04-15 |
| SC 13G | 2024-04-15 |
| SC 13D/A | 2024-04-10 |
| 4 | 2024-04-08 |
| 4 | 2024-04-03 |
| SC 13D/A | 2024-04-03 |
| SC 13D | 2024-03-20 |
View Perceptive Advisors's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.