Perceptive Advisors Q4 2021 holdings

$6.48 Billion is the total value of Perceptive Advisors's 145 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 29.3% .

 Value Shares↓ Weighting
 TRAVERE THERAPEUTICS INCnote 2.500% 9/1$484,736
+6.6%
45,000,0000.0%7.48%
+13.2%
MRTX SellMIRATI THERAPEUTICS INC$481,698
-19.6%
3,283,783
-3.1%
7.43%
-14.6%
NewLIANBIOsponsored ads$346,93156,319,960
+100.0%
5.35%
FOLD  AMICUS THERAPEUTICS INC$306,762
+20.9%
26,559,4430.0%4.73%
+28.5%
SWTX  SPRINGWORKS THERAPEUTICS INC$300,598
-2.3%
4,849,9120.0%4.64%
+3.8%
IOVA SellIOVANCE BIOTHERAPEUTICS INC$193,342
-31.8%
10,127,941
-11.9%
2.98%
-27.5%
HZNP SellHORIZON THERAPEUTICS PUB L$187,301
-12.6%
1,738,140
-11.2%
2.89%
-7.2%
 COLLEGIUM PHARMACEUTICAL INCnote 2.625% 2/1$169,313
-6.1%
17,500,0000.0%2.61%
-0.2%
MGTX  MEIRAGTX HLDGS PLC$164,952
+80.1%
6,948,2770.0%2.54%
+91.4%
CERE  CEREVEL THERAPEUTICS HLDNG I$164,911
+9.9%
5,086,7270.0%2.54%
+16.7%
CRNX BuyCRINETICS PHARMACEUTICALS IN$146,696
+75.8%
5,163,517
+30.3%
2.26%
+86.8%
RXDX SellPROMETHEUS BIOSCIENCES INC$125,452
+59.7%
3,172,785
-4.3%
1.94%
+69.7%
VBIV SellVBI VACCINES INC CDA$122,463
-28.5%
52,335,002
-4.9%
1.89%
-24.0%
BBIO SellBRIDGEBIO PHARMA INC$118,907
-67.3%
7,128,755
-8.1%
1.84%
-65.3%
ISEE SellIVERIC BIO INC$108,346
-10.7%
6,480,000
-13.3%
1.67%
-5.2%
RAPT BuyRAPT THERAPEUTICS INC$107,529
+19.1%
2,927,565
+0.7%
1.66%
+26.5%
BMRN NewBIOMARIN PHARMACEUTICAL INC$104,2531,180,000
+100.0%
1.61%
 NEVRO CORPnote 2.750% 4/0$101,520
-19.6%
9,000,0000.0%1.57%
-14.6%
GBT SellGLOBAL BLOOD THERAPEUTICS IN$100,979
-10.1%
3,449,915
-21.7%
1.56%
-4.5%
CHRS BuyCOHERUS BIOSCIENCES INC$86,308
+12.4%
5,407,798
+13.1%
1.33%
+19.4%
OM SellOUTSET MED INC$85,884
-12.7%
1,863,397
-6.4%
1.32%
-7.3%
XENE BuyXENON PHARMACEUTICALS INC$75,334
+143.8%
2,411,447
+19.3%
1.16%
+158.8%
LABP  LANDOS BIOPHARMA INC$71,375
-67.1%
14,869,9150.0%1.10%
-65.1%
CCCC SellC4 THERAPEUTICS INC$71,126
-29.5%
2,208,913
-2.2%
1.10%
-25.1%
APLS BuyAPELLIS PHARMACEUTICALS INC$68,636
+238.6%
1,451,700
+136.0%
1.06%
+260.2%
BLU NewBELLUS HEALTH INC NEW$61,5447,645,234
+100.0%
0.95%
ZYME  ZYMEWORKS INC$60,312
-43.6%
3,679,8450.0%0.93%
-40.0%
RLAY  RELAY THERAPEUTICS INC$59,672
-2.6%
1,943,0970.0%0.92%
+3.5%
INBX BuyINHIBRX INC$58,670
+57.1%
1,343,490
+19.8%
0.90%
+66.7%
TVTX SellTRAVERE THERAPEUTICS INC$57,286
+20.2%
1,845,555
-6.1%
0.88%
+27.7%
ALBO  ALBIREO PHARMA INC$54,968
-25.4%
2,360,1390.0%0.85%
-20.7%
CCXI BuyCHEMOCENTRYX INC$51,536
+448.0%
1,415,446
+157.4%
0.80%
+480.3%
 COHERUS BIOSCIENCES INCnote 1.500% 4/1$51,489
+4.3%
4,500,0000.0%0.79%
+10.7%
NAUT BuyNAUTILUS BIOTECHNOLOGY INC$47,195
-13.7%
9,111,151
+2.2%
0.73%
-8.4%
ARNA NewARENA PHARMACEUTICALS INC$46,470500,000
+100.0%
0.72%
ATHA  ATHIRA PHARMA INC$44,640
+38.9%
3,425,9160.0%0.69%
+47.5%
KOD BuyKODIAK SCIENCES INC$44,098
-0.4%
520,152
+12.8%
0.68%
+5.8%
SellICOSAVAX INC$43,621
-23.3%
1,906,548
-0.8%
0.67%
-18.5%
RCKT SellROCKET PHARMACEUTICALS INC$42,768
-38.1%
1,959,125
-15.2%
0.66%
-34.2%
QTNT  QUOTIENT LTD$41,960
+10.7%
16,200,8180.0%0.65%
+17.4%
NBIX  NEUROCRINE BIOSCIENCES INC$41,138
-11.2%
483,0070.0%0.64%
-5.6%
MORF SellMORPHIC HLDG INC$39,634
-21.1%
836,521
-5.7%
0.61%
-16.2%
ALDX  ALDEYRA THERAPEUTICS INC$39,616
-54.4%
9,903,8790.0%0.61%
-51.6%
OMIC BuySINGULAR GENOMICS SYSTEMS IN$38,539
+12.0%
3,333,824
+8.5%
0.60%
+19.0%
NewISOPLEXIS CORP$37,6374,095,498
+100.0%
0.58%
ACAD NewACADIA PHARMACEUTICALS INC$36,9721,584,052
+100.0%
0.57%
ZNTL NewZENTALIS PHARMACEUTICALS INC$36,192430,544
+100.0%
0.56%
IMTX  IMMATICS N.V$33,600
+3.4%
2,500,0000.0%0.52%
+9.7%
SellPROCEPT BIOROBOTICS CORP$33,220
-47.4%
1,328,285
-19.8%
0.51%
-44.1%
VRCA  VERRICA PHARMACEUTICALS INC$33,071
-26.7%
3,610,4120.0%0.51%
-22.3%
KRON  KRONOS BIO INC$32,903
-35.2%
2,421,1420.0%0.51%
-31.1%
RAIN SellRAIN THERAPEUTICS INC$31,989
-15.7%
2,483,619
-2.1%
0.49%
-10.3%
TARS  TARSUS PHARMACEUTICALS INC$29,169
+4.4%
1,296,4160.0%0.45%
+10.8%
VRDN BuyVIRIDIAN THERAPEUTICS INC$28,134
+20.2%
1,423,053
+0.0%
0.43%
+27.6%
LPTX  LEAP THERAPEUTICS INC$27,463
-19.2%
8,476,4960.0%0.42%
-14.2%
ESTA SellESTABLISHMENT LABS HLDGS INC$27,411
-24.2%
405,541
-19.8%
0.42%
-19.6%
COGT  COGENT BIOSCIENCES INC$27,359
+2.0%
3,188,7500.0%0.42%
+8.2%
CMAX BuyCAREMAX INC$27,260
-16.6%
3,549,525
+4.9%
0.42%
-11.4%
MGNX SellMACROGENICS INC$26,727
-40.6%
1,665,243
-22.5%
0.41%
-36.9%
VERU  VERU INC$26,218
-31.0%
4,451,3420.0%0.40%
-26.6%
NUVB SellNUVATION BIO INC$24,826
-17.9%
2,920,823
-4.0%
0.38%
-12.8%
LUNG NewPULMONX CORP$24,447762,304
+100.0%
0.38%
NVTA SellINVITAE CORP$24,197
-78.3%
1,584,585
-59.6%
0.37%
-77.0%
SLDB  SOLID BIOSCIENCES INC$23,472
-26.8%
13,412,5520.0%0.36%
-22.3%
NewPYXIS ONCOLOGY INC$21,3261,944,114
+100.0%
0.33%
 CUE HEALTH INC$21,196
+13.5%
1,580,6070.0%0.33%
+20.7%
UTHR SellUNITED THERAPEUTICS CORP DEL$20,325
-22.3%
94,064
-33.6%
0.31%
-17.4%
VRNA SellVERONA PHARMA PLCsponsored ads$19,270
+21.7%
2,867,510
-0.7%
0.30%
+29.1%
NewSCIENCE 37 HOLDINGS INC$18,7051,500,000
+100.0%
0.29%
ATNX  ATHENEX INC$18,404
-54.8%
13,532,4670.0%0.28%
-52.0%
TMCI SellTREACE MED CONCEPTS INC$18,271
-45.0%
980,186
-20.7%
0.28%
-41.6%
HCAT SellHEALTH CATALYST INC$17,988
-38.9%
454,004
-22.9%
0.28%
-35.0%
NewDICE THERAPEUTICS INC$17,841704,885
+100.0%
0.28%
SellSOMALOGIC INC$17,460
-31.3%
1,500,000
-26.8%
0.27%
-27.1%
ADMA SellADMA BIOLOGICS INC$16,826
+12.3%
11,933,387
-10.0%
0.26%
+19.3%
 NUVALENT INC$14,280
-15.6%
750,0000.0%0.22%
-10.6%
LYRA  LYRA THERAPEUTICS INC$14,050
-52.2%
3,222,5600.0%0.22%
-49.2%
VTRS  VIATRIS INC$13,590
-0.1%
1,004,4190.0%0.21%
+6.1%
SAVA BuyCASSAVA SCIENCES INCput$13,110
+111.2%
300,000
+200.0%
0.20%
+124.4%
BCAB SellBIOATLA INC$12,979
-48.1%
661,200
-22.2%
0.20%
-45.1%
IMCR SellIMMUNOCORE HLDGS PLCads$12,326
-16.9%
360,000
-10.0%
0.19%
-11.6%
 NANOSTRING TECHNOLOGIES INCnote 2.625% 3/0$11,983
-6.4%
1,000,0000.0%0.18%
-0.5%
BIIB  BIOGEN INC$11,660
-15.2%
48,6000.0%0.18%
-10.0%
SellABSCI CORPORATION$11,577
-32.6%
1,411,776
-4.4%
0.18%
-28.1%
ACRS  ACLARIS THERAPEUTICS INC$11,359
-19.2%
781,2360.0%0.18%
-14.2%
MRUS NewMERUS N V$11,130350,000
+100.0%
0.17%
 SEMA4 HOLDINGS CORP$11,150
-41.2%
2,500,0000.0%0.17%
-37.7%
 IMMUNEERING CORP$11,013
-39.1%
681,0510.0%0.17%
-35.4%
NewHYPERFINE INC$10,8751,500,000
+100.0%
0.17%
 ASTRIA THERAPEUTICS INC$10,562
-39.0%
1,959,6520.0%0.16%
-35.3%
GRPH SellGRAPHITE BIO INC$10,567
-26.3%
850,093
-2.9%
0.16%
-21.6%
AGRX BuyAGILE THERAPEUTICS INC$10,394
-32.1%
21,294,485
+33.8%
0.16%
-27.9%
HRMY SellHARMONY BIOSCIENCES HLDGS IN$10,202
-45.8%
239,258
-51.3%
0.16%
-42.7%
SMIHU  SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026$9,950
-1.0%
1,000,0000.0%0.15%
+5.5%
ADPT  ADAPTIVE BIOTECHNOLOGIES COR$9,900
-17.4%
352,8040.0%0.15%
-12.1%
KYMR SellKYMERA THERAPEUTICS INC$9,841
-6.9%
155,000
-13.9%
0.15%
-1.3%
RACB  RESEARCH ALLIANCE CORP II$9,770
-0.8%
1,000,0000.0%0.15%
+5.6%
BLSA  BCLS ACQUISITION CORP$9,800
-1.6%
1,000,0000.0%0.15%
+4.1%
SellTYRA BIOSCIENCES INC$9,474
-45.5%
673,352
-31.8%
0.15%
-42.1%
DAWN  DAY ONE BIOPHARMACEUTICALS I$9,369
-29.0%
556,0470.0%0.14%
-24.5%
ONEM  1LIFE HEALTHCARE INC$9,353
-13.2%
532,3500.0%0.14%
-8.3%
CLDX SellCELLDEX THERAPEUTICS INC NEW$8,880
-58.2%
229,807
-41.6%
0.14%
-55.7%
LEGN NewLEGEND BIOTECH CORPsponsored ads$8,814189,100
+100.0%
0.14%
NBTX  NANOBIOTIX SAsponsored ads$8,584
-28.7%
1,059,8000.0%0.13%
-24.6%
NewEQRX INC$8,5251,250,000
+100.0%
0.13%
MDGL NewMADRIGAL PHARMACEUTICALS INC$7,32286,400
+100.0%
0.11%
 SIGHT SCIENCES INC$6,852
-22.6%
390,0000.0%0.11%
-17.8%
CNCE  CONCERT PHARMACEUTICALS INC$6,774
-3.7%
2,150,6410.0%0.10%
+2.9%
PNT SellPOINT BIOPHARMA GLOBAL INC$6,686
-30.0%
1,193,995
-3.9%
0.10%
-25.9%
CRY NewCRYOLIFE INC$6,641326,318
+100.0%
0.10%
ACCD SellACCOLADE INC$6,030
-48.9%
228,774
-18.2%
0.09%
-45.6%
CLOV  CLOVER HEALTH INVESTMENTS CO$5,580
-49.7%
1,500,0000.0%0.09%
-46.6%
PRVB  PROVENTION BIO INC$5,330
-12.2%
948,4810.0%0.08%
-6.8%
ONCR SellONCORUS INC$5,269
-48.7%
999,812
-9.1%
0.08%
-45.6%
FULC  FULCRUM THERAPEUTICS INC$5,203
-37.3%
294,1180.0%0.08%
-33.9%
FUSN SellFUSION PHARMACEUTICALS INC$5,117
-48.5%
1,227,017
-2.2%
0.08%
-45.1%
NewENVVENO MEDICAL CORPORATION$5,150781,615
+100.0%
0.08%
PRTA  PROTHENA CORP PLC$4,940
-30.6%
100,0000.0%0.08%
-26.2%
 DA32 LIFE SCNCE TEC ACQSTN C$4,905
-0.2%
500,0000.0%0.08%
+7.0%
DNAY  CODEX DNA INC$4,590
-3.0%
425,0000.0%0.07%
+2.9%
HSAQ  HEALTH SCIENCES ACQ CORP 2$4,536
+1.9%
450,0000.0%0.07%
+7.7%
 DARIOHEALTH CORP$4,252
-5.0%
327,8690.0%0.07%
+1.5%
NEPT  NEPTUNE WELLNESS SOLUTIONS I$4,123
-32.2%
10,055,5210.0%0.06%
-27.3%
BuyRAPID MICRO BIOSYSTEMS INC$4,104
-36.5%
385,693
+10.2%
0.06%
-33.0%
NewSONENDO INC$3,851668,505
+100.0%
0.06%
ACHL  ACHILLES THERAPEUTICS PLCsponsored ads$3,784
-35.7%
755,3750.0%0.06%
-31.8%
AXSM  AXSOME THERAPEUTICS INC$3,038
+14.6%
80,4200.0%0.05%
+20.5%
PMVP SellPMV PHARMACEUTICALS INC$2,888
-67.9%
125,000
-58.6%
0.04%
-65.6%
TARA  PROTARA THERAPEUTICS INC$2,846
-2.5%
421,6410.0%0.04%
+4.8%
SellSURROZEN INC$2,663
-24.8%
413,446
-17.3%
0.04%
-19.6%
VYNE SellVYNE THERAPEUTICS INC$2,222
-31.4%
2,178,022
-6.5%
0.03%
-27.7%
DCPH NewDECIPHERA PHARMACEUTICALS INcall$1,954200,000
+100.0%
0.03%
NVRO SellNEVRO CORP$1,860
-93.9%
22,946
-91.2%
0.03%
-93.4%
RACE  FERRARI N V$1,605
+23.7%
6,2000.0%0.02%
+31.6%
ITOS NewITEOS THERAPEUTICS INC$93120,000
+100.0%
0.01%
MOTS  MOTUS GI HLDGS INC$841
-32.3%
1,800,5420.0%0.01%
-27.8%
EIGR  EIGER BIOPHARMACEUTICALS INC$726
-22.3%
139,8900.0%0.01%
-21.4%
 ROCKLEY PHOTONICS HOLDINGS L*w exp 08/11/202$605
-49.4%
500,0000.0%0.01%
-47.1%
NewMINERVA SURGICAL INC$45187,768
+100.0%
0.01%
 SOMALOGIC INC*w exp 08/31/202$367
-3.4%
110,0000.0%0.01%0.0%
PHVS  PHARVARIS N V$389
-18.8%
27,0000.0%0.01%
-14.3%
BFLYWS  BUTTERFLY NETWORK INC*w exp 02/12/202$296
-53.9%
233,3330.0%0.01%
-44.4%
NewEQRX INC*w exp 12/17/202$266250,000
+100.0%
0.00%
 SURROZEN INC*w exp 08/01/203$192
+1.1%
166,6660.0%0.00%0.0%
CMAXW  CAREMAX INC*w exp 06/08/202$84
-50.6%
60,0000.0%0.00%
-50.0%
FREQ ExitFREQUENCY THERAPEUTICS INC$0-222,222
-100.0%
-0.02%
ExitIMAGO BIOSCIENCES INC$0-125,000
-100.0%
-0.04%
LSAQ ExitLIFESCI ACQUISITION II CORP$0-300,000
-100.0%
-0.04%
RGNX ExitREGENXBIO INC$0-89,283
-100.0%
-0.05%
ATEC ExitALPHATEC HLDGS INC$0-430,900
-100.0%
-0.08%
PSTX ExitPOSEIDA THERAPEUTICS INC$0-787,745
-100.0%
-0.08%
TSHA ExitTAYSHA GENE THERAPIES INC$0-320,440
-100.0%
-0.09%
FDMT Exit4D MOLECULAR THERAPEUTICS IN$0-375,256
-100.0%
-0.15%
ZY ExitZYMERGEN INC$0-883,332
-100.0%
-0.17%
PODD ExitINSULET CORP$0-44,522
-100.0%
-0.18%
CMLTU ExitCM LIFE SCIENCES III INCunit 04/30/2028$0-1,250,000
-100.0%
-0.19%
HCAQ ExitHEALTHCOR CATALIO ACQU CORP$0-1,500,000
-100.0%
-0.22%
CCXI ExitCHEMOCENTRYX INCcall$0-923,200
-100.0%
-0.23%
NTRA ExitNATERA INC$0-160,000
-100.0%
-0.26%
RNA ExitAVIDITY BIOSCIENCES INC$0-885,818
-100.0%
-0.32%
DBVT ExitDBV TECHNOLOGIES S Asponsored adr$0-7,695,505
-100.0%
-0.55%
BEAM ExitBEAM THERAPEUTICS INC$0-537,635
-100.0%
-0.68%
AVIR ExitATEA PHARMACEUTICALS INC$0-2,259,224
-100.0%
-1.15%
Signed by
  • Joseph Edelman — Managing Member

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