$3.54 Billion is the total value of Perceptive Advisors's 105 reported holdings in Q1 2019. The portfolio turnover from Q4 2018 to Q1 2019 was 57.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $331,138,000 | +5.0% | 3,758,662 | -18.4% | 9.34% | -22.2% |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $294,297,000 | +53.5% | 21,639,486 | +4.4% | 8.30% | +13.8% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS INC | $292,476,000 | +31.3% | 5,525,726 | +1.8% | 8.25% | -2.6% |
| ZGNX | Buy | ZOGENIX INC | $212,860,000 | +54.0% | 3,869,491 | +2.1% | 6.01% | +14.2% |
| AMRN | Buy | AMARIN CORPORATION PLCspons adr new | $135,790,000 | +110.4% | 6,540,957 | +34.2% | 3.83% | +55.9% |
| ASND | Buy | ASCENDIS PHARMA A Ssponsored adr | $131,039,000 | +107.9% | 1,113,328 | +5.8% | 3.70% | +54.1% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $116,362,000 | +7.4% | 12,235,811 | -0.0% | 3.28% | -20.4% |
| MGTX | Buy | MEIRAGTX HOLDINGS PLC | $103,513,000 | +128.3% | 6,007,746 | +27.7% | 2.92% | +69.2% |
| ARRY | New | ARRAY BIOPHARMA INC | $103,101,000 | – | 4,228,900 | +100.0% | 2.91% | – |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $101,748,000 | +134.0% | 1,271,054 | +48.3% | 2.87% | +73.5% |
| QTNT | QUOTIENT LTD | $97,209,000 | +47.2% | 10,789,054 | 0.0% | 2.74% | +9.2% | |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $85,349,000 | +1525.7% | 1,164,382 | +825.0% | 2.41% | +1104.0% |
| RTRX | Sell | RETROPHIN INC | $69,128,000 | +38.9% | 3,054,707 | -8.6% | 1.95% | +2.9% |
| RGNX | Buy | REGENXBIO INC | $65,662,000 | +144.2% | 1,145,726 | +77.4% | 1.85% | +81.0% |
| MMSI | Buy | MERIT MEDICAL SYSTEMS INC | $65,113,000 | +24.8% | 1,053,098 | +10.9% | 1.84% | -7.5% |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $62,770,000 | +12.9% | 1,400,171 | -2.1% | 1.77% | -16.3% |
| ATNX | ATHENEX INC | $62,426,000 | +91.8% | 5,096,022 | 0.0% | 1.76% | +42.1% | |
| CRNX | CRINETICS PHARMACEUTICALS INC | $58,901,000 | -24.1% | 2,587,953 | 0.0% | 1.66% | -43.7% | |
| CBAY | Buy | CYMABAY THERAPEUTICS INC | $55,946,000 | +188.6% | 4,212,821 | +71.1% | 1.58% | +113.8% |
| ALBO | ALBIREO PHARMA INC | $54,896,000 | +39.0% | 1,704,330 | 0.0% | 1.55% | +3.0% | |
| MYOK | Sell | MYOKARDIA INC | $51,393,000 | -3.9% | 988,511 | -8.1% | 1.45% | -28.8% |
| NVTA | Buy | INVITAE CORP | $50,866,000 | +146.8% | 2,171,918 | +16.6% | 1.44% | +83.0% |
| ALLO | ALLOGENE THERAPEUTICS INC | $44,630,000 | +7.4% | 1,543,790 | 0.0% | 1.26% | -20.4% | |
| VBIV | VBI VACCINES INC | $42,633,000 | +11.2% | 23,951,556 | 0.0% | 1.20% | -17.5% | |
| MNTA | Buy | MOMENTA PHARMACEUTICALS INC | $41,774,000 | +34.2% | 2,875,000 | +1.8% | 1.18% | -0.5% |
| VRCA | VERRICA PHARMACEUTICALS INC | $38,537,000 | +38.7% | 3,410,412 | 0.0% | 1.09% | +2.7% | |
| New | SOLID BIOSCIENCES INC | $36,130,000 | – | 3,927,222 | +100.0% | 1.02% | – | |
| VRAY | Buy | VIEWRAY INC | $35,514,000 | +63.5% | 4,805,650 | +23.0% | 1.00% | +21.3% |
| KDMN | KADMON HOLDINGS INC | $34,757,000 | +26.9% | 13,165,746 | 0.0% | 0.98% | -5.9% | |
| CTMX | Buy | CYTOMX THERAPEUTICS INC | $34,120,000 | -21.7% | 3,173,923 | +9.0% | 0.96% | -42.0% |
| NEPT | NEPTUNE WELLNESS SOLUTIONS INC | $28,363,000 | +58.9% | 8,891,452 | 0.0% | 0.80% | +17.8% | |
| ALDX | ALDEYRA THERAPEUTICS INC | $27,862,000 | +12.9% | 3,085,458 | 0.0% | 0.79% | -16.3% | |
| DOVA | DOVA PHARMACEUTICALS INC | $27,788,000 | +17.3% | 3,125,851 | 0.0% | 0.78% | -13.1% | |
| TDOC | Buy | TELADOC HEALTH INC | $27,522,000 | +825.4% | 495,000 | +725.0% | 0.78% | +587.6% |
| CNCE | Buy | CONCERT PHARMACEUTICALS INC | $26,610,000 | +16.6% | 2,204,641 | +17.7% | 0.75% | -13.6% |
| NVRO | New | NEVRO CORP | $26,063,000 | – | 416,949 | +100.0% | 0.74% | – |
| Buy | PROTAGONIST THERAPEUTICS INC | $26,036,000 | +183.3% | 2,071,297 | +51.7% | 0.74% | +110.0% | |
| ADMA | ADMA BIOLOGICS INC | $24,715,000 | +70.0% | 6,521,102 | 0.0% | 0.70% | +26.0% | |
| VAPO | Buy | VAPOTHERM INC | $24,490,000 | +0.1% | 1,246,315 | +1.6% | 0.69% | -25.8% |
| KOD | KODIAK SCIENCES INC | $20,472,000 | -8.0% | 3,135,199 | 0.0% | 0.58% | -31.8% | |
| EHTH | Buy | EHEALTH INC | $18,070,000 | +755.2% | 289,857 | +426.8% | 0.51% | +537.5% |
| FOMX | FOAMIX PHARMACEUTICALS LTD | $17,482,000 | +10.3% | 4,661,824 | 0.0% | 0.49% | -18.2% | |
| AXNX | Sell | AXONICS MODULATION TECHNOLOGIES INC | $16,424,000 | +50.2% | 685,756 | -8.7% | 0.46% | +11.3% |
| EIDX | Buy | EIDOS THERAPEUTICS INC | $16,109,000 | +70.4% | 686,992 | +0.0% | 0.46% | +26.4% |
| IRTC | New | IRHYTHM TECHNOLOGIES INC | $14,992,000 | – | 200,000 | +100.0% | 0.42% | – |
| BHC | New | BAUSCH HEALTH COS INC | $14,820,000 | – | 600,000 | +100.0% | 0.42% | – |
| ESTA | ESTABLISHMENT LABS HLDGS INC | $14,766,000 | -7.0% | 614,242 | 0.0% | 0.42% | -31.0% | |
| AQUESTIVE THERAPEUTICS INC | $14,603,000 | +9.7% | 2,113,400 | 0.0% | 0.41% | -18.7% | ||
| AKBA | AKEBIA THERAPEUTICS INC | $13,951,000 | +51.9% | 1,703,440 | 0.0% | 0.39% | +12.9% | |
| QURE | Buy | UNIQURE NV. | $13,828,000 | +132.6% | 231,820 | +5.0% | 0.39% | +72.6% |
| RYTM | Sell | RHYTHM PHARMACEUTICALS INC | $13,786,000 | +0.2% | 502,970 | -1.2% | 0.39% | -25.8% |
| MEIP | MEI PHARMA INC | $13,509,000 | +16.3% | 4,400,440 | 0.0% | 0.38% | -13.8% | |
| MRKR | MARKER THERAPEUTICS INC | $13,200,000 | +18.9% | 2,000,000 | 0.0% | 0.37% | -11.8% | |
| AGRX | New | AGILE THERAPEUTICS INC | $12,724,000 | – | 8,426,750 | +100.0% | 0.36% | – |
| MOTS | MOTUS GI HLDGS INC | $12,521,000 | +25.4% | 3,210,542 | 0.0% | 0.35% | -7.1% | |
| MTEM | MOLECULAR TEMPLATES INC | $11,470,000 | +61.4% | 1,974,133 | 0.0% | 0.32% | +20.0% | |
| PRQR | PROQR THERAPEUTICS N.V. | $10,021,000 | -10.9% | 722,523 | 0.0% | 0.28% | -33.9% | |
| ALEC | New | ALECTOR INC | $9,579,000 | – | 511,731 | +100.0% | 0.27% | – |
| ORTX | ORCHARD THERAPEUTICS PLCads | $9,329,000 | +13.7% | 521,800 | 0.0% | 0.26% | -15.7% | |
| HUM | New | HUMANA INC | $9,310,000 | – | 35,000 | +100.0% | 0.26% | – |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $8,700,000 | +63.9% | 1,128,524 | +36.5% | 0.24% | +21.3% |
| UROV | Buy | UROVANT SCIENCES LTD | $8,697,000 | +122.1% | 865,359 | +38.4% | 0.24% | +64.4% |
| ZYME | ZYMEWORKS INC | $8,529,000 | +18.5% | 573,890 | 0.0% | 0.24% | -12.0% | |
| ANI PHARMACEUTICALS INCnote 3.000%12/0 | $8,239,000 | +11.6% | 7,500,000 | 0.0% | 0.23% | -17.4% | ||
| RCKT | Buy | ROCKET PHARMACEUTICALS INC | $8,036,000 | +129.9% | 458,173 | +90.8% | 0.23% | +70.7% |
| SYBX | SYNLOGIC INC | $6,587,000 | +8.9% | 867,852 | 0.0% | 0.19% | -19.1% | |
| ARWR | Buy | ARROWHEAD PHARMACEUTICALS INC | $6,069,000 | +69.4% | 330,738 | +10.2% | 0.17% | +25.7% |
| SWAV | New | SHOCKWAVE MEDICAL INC | $5,021,000 | – | 150,000 | +100.0% | 0.14% | – |
| SRRA | SIERRA ONCOLOGY INC | $4,559,000 | +33.6% | 2,666,190 | 0.0% | 0.13% | -0.8% | |
| TBIO | TRANSLATE BIO INC | $4,433,000 | +40.0% | 435,000 | 0.0% | 0.12% | +3.3% | |
| LIVN | New | LIVANOVA PLC | $3,890,000 | – | 40,000 | +100.0% | 0.11% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL INC | $3,468,000 | – | 50,000 | +100.0% | 0.10% | – |
| XENT | New | INTERSECT ENT INC | $2,251,000 | – | 70,000 | +100.0% | 0.06% | – |
| VERU | VERU INC | $2,081,000 | +12.3% | 1,425,000 | 0.0% | 0.06% | -16.9% | |
| EIGR | EIGER BIOPHARMACEUTICALS INC | $1,955,000 | +37.6% | 139,890 | 0.0% | 0.06% | +1.9% | |
| ABEOW | ABEONA THERAPEUTICS INC*w exp 12/24/201 | $1,906,000 | +50.4% | 659,636 | 0.0% | 0.05% | +12.5% | |
| ACST | ACASTI PHARMA INCcl a new | $1,815,000 | +22.6% | 1,779,882 | 0.0% | 0.05% | -8.9% | |
| OMED | ONCOMED PHARMACEUTICALS INC | $1,787,000 | +39.2% | 1,719,111 | 0.0% | 0.05% | +2.0% | |
| VCRA | New | VOCERA COMMUNICATIONS INC | $1,582,000 | – | 50,000 | +100.0% | 0.04% | – |
| CRY | New | CRYOLIFE INC | $1,459,000 | – | 50,000 | +100.0% | 0.04% | – |
| ABEO | ABEONA THERAPEUTICS INC | $1,331,000 | +4.9% | 180,797 | 0.0% | 0.04% | -20.8% | |
| AVDR | New | AVEDRO INC | $1,227,000 | – | 100,000 | +100.0% | 0.04% | – |
| ALNA | ALLENA PHARMACEUTICALS INC | $929,000 | +32.0% | 132,300 | 0.0% | 0.03% | -3.7% | |
| New | FIAT CHRYSLER AUTOMOBILES N | $920,000 | – | 62,000 | +100.0% | 0.03% | – | |
| RACE | FERRARI N.V. | $830,000 | +36.1% | 6,200 | 0.0% | 0.02% | 0.0% | |
| TNDM | TANDEM DIABETES CARE INC | $816,000 | +70.4% | 12,844 | 0.0% | 0.02% | +27.8% | |
| VCYT | New | VERACYTE INC | $789,000 | – | 31,521 | +100.0% | 0.02% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $767,000 | – | 53,879 | +100.0% | 0.02% | – |
| CLVS | New | CLOVIS ONCOLOGY INCput | $660,000 | – | 200,000 | +100.0% | 0.02% | – |
| BIIB | New | BIOGEN INCcall | $620,000 | – | 400,000 | +100.0% | 0.02% | – |
| FLDM | New | FLUIDIGM CORP | $612,000 | – | 46,030 | +100.0% | 0.02% | – |
| FGEN | New | FIBROGEN INC | $506,000 | – | 9,306 | +100.0% | 0.01% | – |
| VCEL | VERICEL CORP | $492,000 | +0.8% | 28,090 | 0.0% | 0.01% | -26.3% | |
| SRPT | New | SAREPTA THERAPEUTICS INCcall | $421,000 | – | 100,000 | +100.0% | 0.01% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $400,000 | – | 14,897 | +100.0% | 0.01% | – |
| BEAT | New | BIOTELEMETRY INC | $399,000 | – | 6,369 | +100.0% | 0.01% | – |
| EOLS | New | EVOLUS INC | $344,000 | – | 15,232 | +100.0% | 0.01% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INCcall | $140,000 | – | 200,000 | +100.0% | 0.00% | – |
| CLVS | New | CLOVIS ONCOLOGY INCcall | $125,000 | – | 200,000 | +100.0% | 0.00% | – |
| OTLKW | OUTLOOK THERAPEUTICS INC*w exp 02/18/202 | $159,000 | +120.8% | 420,875 | 0.0% | 0.00% | +33.3% | |
| IMMU | IMMUNOMEDICS INCcall | $125,000 | -59.4% | 200,000 | 0.0% | 0.00% | -66.7% | |
| New | SOLID BIOSCIENCES INCcall | $29,000 | – | 10,000 | +100.0% | 0.00% | – | |
| ASND | New | ASCENDIS PHARMA A Sput | $25,000 | – | 200,000 | +100.0% | 0.00% | – |
| ONCS | Sell | ONCOSEC MEDICAL INC | $17,000 | -46.9% | 30,000 | -40.0% | 0.00% | -100.0% |
| IMGN | New | IMMUNOGEN INCcall | $15,000 | – | 600,000 | +100.0% | 0.00% | – |
| SLDB | Exit | SOLID BIOSCIENCES INCcall | $0 | – | -1,835 | -100.0% | -0.00% | – |
| VCNX | Exit | VACCINEX INC | $0 | – | -50,000 | -100.0% | -0.01% | – |
| ALQA | Exit | ALLIQUA BIOMEDICAL INC | $0 | – | -114,730 | -100.0% | -0.01% | – |
| SIBN | Exit | SI-BONE INC | $0 | – | -15,000 | -100.0% | -0.01% | – |
| STAA | Exit | STAAR SURGICAL CO | $0 | – | -12,953 | -100.0% | -0.02% | – |
| AMED | Exit | AMEDISYS INC | $0 | – | -3,672 | -100.0% | -0.02% | – |
| GKOS | Exit | GLAUKOS CORP | $0 | – | -7,466 | -100.0% | -0.02% | – |
| ZGNX | Exit | ZOGENIX INCput | $0 | – | -200,000 | -100.0% | -0.02% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -3,733 | -100.0% | -0.02% | – |
| Exit | PERNIX THERAPEUTICS HLDGS INdbcv 4,250% 4/0 | $0 | – | -1,000,000 | -100.0% | -0.02% | – | |
| IVC | Exit | INVACARE CORP | $0 | – | -200,000 | -100.0% | -0.03% | – |
| FCAU | Exit | FIAT CHRYSLER AUTOMOBILES N. | $0 | – | -62,000 | -100.0% | -0.03% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -300,000 | -100.0% | -0.04% | – |
| CDNA | Exit | CAREDX INC | $0 | – | -44,128 | -100.0% | -0.04% | – |
| PEN | Exit | PENUMBRA INC | $0 | – | -16,338 | -100.0% | -0.08% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -59,498 | -100.0% | -0.10% | – |
| TXMD | Exit | THERAPEUTICSMD INC | $0 | – | -1,500,000 | -100.0% | -0.22% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -196,810 | -100.0% | -0.26% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -445,000 | -100.0% | -0.28% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -700,000 | -100.0% | -0.40% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -147,315 | -100.0% | -0.50% | – |
| CMTA | Exit | CLEMENTIA PHARMACEUTICALS INC | $0 | – | -1,500,000 | -100.0% | -0.67% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -262,241 | -100.0% | -0.70% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -905,017 | -100.0% | -1.52% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -4,313,611 | -100.0% | -1.56% | – |
| ARGX | Exit | ARGENX SEsponsored adr | $0 | – | -560,941 | -100.0% | -2.05% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -3,927,222 | -100.0% | -4.01% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR/A filed 2019-05-16
About Perceptive Advisors
Perceptive Advisors is a New York-based hedge fund that specializes in healthcare investments. The company was founded in 1999 by Joseph Edelman, who serves as the CEO and Chief Investment Officer. Since its inception, Perceptive Advisors has become one of the most successful healthcare-focused hedge funds in the world, with over $5 billion in assets under management.
The company's investment strategy is based on a deep understanding of the healthcare industry and a focus on identifying promising companies with innovative products and technologies. Perceptive Advisors invests in a wide range of healthcare sectors, including biotechnology, pharmaceuticals, medical devices, and healthcare services.
One of the key factors behind Perceptive Advisors' success is its team of experienced professionals. In addition to Joseph Edelman, the company's leadership team includes Adam Stone, the COO, and Jeremy Goldberg, the Chief Scientific Officer. The team also includes a group of highly skilled analysts and researchers who are experts in their respective fields.
Perceptive Advisors has a strong track record of generating high returns for its investors. However, it is important to note that investing in hedge funds carries significant risks, and investors should carefully consider their investment objectives and risk tolerance before investing. As with any investment, it is important to conduct thorough research and seek the advice of a qualified financial advisor before making any investment decisions.
It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES SHARES | 42 | Q3 2023 | 15.7% |
| AMICUS THERAPEUTICS SHARES | 39 | Q3 2023 | 14.0% |
| ALDEYRA THERAPEUTICS SHARES | 35 | Q3 2023 | 3.3% |
| QUOTIENT TECHNOLOGY INC | 34 | Q3 2022 | 2.7% |
| GLOBAL BLOOD THERAPEUTICS SHARES | 29 | Q3 2022 | 9.3% |
| ADMA BIOLOGICS SHARES | 29 | Q3 2023 | 1.4% |
| RETROPHIN SHARES | 28 | Q3 2020 | 5.5% |
| DBV TECHNOLOGIES SA-SPON ADR | 28 | Q3 2021 | 1.8% |
| VBI VACCINES SHARES | 27 | Q1 2023 | 2.8% |
| IOVANCE BIOTHERAPEUTICS INC | 26 | Q3 2023 | 9.1% |
View Perceptive Advisors's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| CHEMBIO DIAGNOSTICS, INC.Sold out | May 04, 2023 | 0 | 0.0% |
| VBI Vaccines Inc/BC | April 07, 2023 | 43,509,553 | 16.7% |
| Landos Biopharma, Inc. | March 30, 2023 | 14,869,915 | 47.7% |
| REATA PHARMACEUTICALS INC | March 07, 2023 | 2,083,799 | 6.5% |
| AGILE THERAPEUTICS INCSold out | February 14, 2023 | 0 | 0.0% |
| ALBIREO PHARMA, INC. | February 14, 2023 | 1,757,160 | 8.5% |
| BELLUS Health Inc. | February 14, 2023 | 8,891,027 | 7.1% |
| CinCor Pharma, Inc. | February 14, 2023 | 2,576,325 | 5.9% |
| Coherus BioSciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| CONCERT PHARMACEUTICALS, INC. | February 14, 2023 | 1,800,000 | 3.6% |
View Perceptive Advisors's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-04-17 |
| 4 | 2024-04-15 |
| SC 13G/A | 2024-04-15 |
| SC 13G | 2024-04-15 |
| SC 13D/A | 2024-04-10 |
| 4 | 2024-04-08 |
| 4 | 2024-04-03 |
| SC 13D/A | 2024-04-03 |
| SC 13D | 2024-03-20 |
View Perceptive Advisors's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.