Perceptive Advisors - Q3 2014 holdings

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$931 Million is the total value of Perceptive Advisors's 125 reported holdings in Q3 2014. The portfolio turnover from Q2 2014 to Q3 2014 was 75.2% .

All

			Value		Shares		↓ Weighting
FOLD		AMICUS THERAPEUTICS INC	$73,420,000	+78.1%	12,339,444	0.0%	7.88%	+95.0%
NBIX	Sell	NEUROCRINE BIOSCIENCES INC	$71,538,000	+4.8%	4,565,267	-0.8%	7.68%	+14.7%
SRPT	Buy	SAREPTA THERAPEUTICS INC	$54,790,000	-28.1%	2,596,691	+1.5%	5.88%	-21.3%
ACRX		ACELRX PHARMACEUTICALS INC	$36,092,000	-46.4%	6,574,060	0.0%	3.88%	-41.4%
CELG	Sell	CELGENE CORP	$35,775,000	-17.9%	377,448	-25.6%	3.84%	-10.2%
PTCT		PTC THERAPEUTICS INC	$29,563,000	+68.4%	671,736	0.0%	3.17%	+84.2%
DYAX	Buy	DYAX CORP	$28,695,000	+10.3%	2,835,498	+4.6%	3.08%	+20.7%
ACAD	Buy	ACADIA PHARMACEUTICALS INC	$27,184,000	+84.3%	1,097,914	+68.1%	2.92%	+101.7%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$26,970,000	-39.4%	240,142	-48.9%	2.90%	-33.7%
SRPT	New	Sarepta Therapeutics Inccall	$26,375,000	–	1,250,000	+100.0%	2.83%	–
ZBH	Buy	ZIMMER HLDGS INC	$25,389,000	+0.8%	252,500	+4.1%	2.73%	+10.3%
TARO	Sell	TARO PHARMACEUTICAL INDS LTD	$21,684,000	-48.7%	140,935	-53.2%	2.33%	-43.8%
LBIO	Sell	LION BIOTECHNOLOGIES	$20,839,000	+8.1%	2,914,549	-3.2%	2.24%	+18.4%
OPHT	Buy	OPHTHOTECH CORP	$20,250,000	+28.8%	520,165	+40.0%	2.17%	+41.0%
OTIC	New	OTONOMY INC	$20,098,000	–	837,400	+100.0%	2.16%	–
RCPT	Buy	RECEPTOS INC	$19,477,000	+123.0%	313,594	+53.0%	2.09%	+144.0%
TSRO	Buy	TESARO INC	$19,067,000	-3.8%	708,284	+11.2%	2.05%	+5.3%
ARWR	Buy	ARROWHEAD RESH CORP	$18,426,000	+204.8%	1,247,495	+195.3%	1.98%	+233.7%
XNCR	Buy	XENCOR INC	$17,900,000	-11.5%	1,922,707	+10.5%	1.92%	-3.1%
HCA	Buy	HCA HOLDINGS INC	$16,241,000	+45.6%	230,306	+16.4%	1.74%	+59.4%
RLYP	Buy	RELYPSA INC	$16,085,000	+10.9%	762,705	+27.8%	1.73%	+21.4%
XLRN	Buy	ACCELERON PHARMA INC	$13,457,000	+32.0%	445,000	+48.3%	1.44%	+44.5%
RTRX	Buy	RETROPHIN INC	$12,438,000	-16.9%	1,379,137	+8.2%	1.34%	-9.0%
AEGR	New	AEGERION PHARMACEUTICALS INC	$12,242,000	–	366,754	+100.0%	1.32%	–
NBIX	New	NEUROCRINE BIOSCIENCES INCput	$10,233,000	–	653,000	+100.0%	1.10%	–
VSAR	Buy	VERSARTIS INC	$9,253,000	+4.5%	487,262	+54.3%	0.99%	+14.4%
NEPT		NEPTUNE TECHNOLOGIES BIORESO	$9,072,000	-50.9%	6,700,444	0.0%	0.97%	-46.3%
AGN		ALLERGAN INC	$8,910,000	+5.3%	50,000	0.0%	0.96%	+15.3%
FLML	Sell	FLAMEL TECHNOLOGIES SAsponsored adr	$8,729,000	-27.3%	610,000	-23.8%	0.94%	-20.4%
SGMO		SANGAMO BIOSCIENCES INC	$8,628,000	-29.4%	800,000	0.0%	0.93%	-22.7%
ADHD	New	ALCOBRA LTDcall	$8,291,000	–	537,000	+100.0%	0.89%	–
INSM	Sell	INSMED INC	$7,830,000	-78.2%	600,000	-66.7%	0.84%	-76.2%
EPZM	Buy	EPIZYME INC	$7,696,000	+480.4%	283,890	+566.4%	0.83%	+535.4%
ADHD	New	ALCOBRA LTDput	$7,519,000	–	487,000	+100.0%	0.81%	–
HRTX	Sell	HERON THERAPEUTICS INC	$7,375,000	-63.4%	885,352	-45.8%	0.79%	-59.9%
VNDA	New	VANDA PHARMACEUTICALS INCput	$7,266,000	–	700,000	+100.0%	0.78%	–
PRTA	Sell	PROTHENA CORP PLC	$6,648,000	-39.0%	300,000	-37.9%	0.71%	-33.2%
SAGE	New	SAGE THERAPEUTICS INC	$6,573,000	–	208,676	+100.0%	0.71%	–
AFMD	New	AFFIMED THERAPEUTICS B V	$6,300,000	–	99,989	+100.0%	0.68%	–
LCI	New	LANNET INC	$6,147,000	–	134,569	+100.0%	0.66%	–
TRXC	Buy	TRANSENTERIX INC	$5,720,000	-12.7%	1,311,941	+0.9%	0.61%	-4.5%
AGTC	Buy	APPLIED GENETIC TECHNOL CORP	$5,527,000	+62.8%	296,978	+102.1%	0.59%	+78.1%
AVNR	New	AVANIR PHARMACEUTICALS INCcl a new	$5,483,000	–	460,000	+100.0%	0.59%	–
AERI		ALLIQUA INC	$5,441,000	+29.7%	1,121,951	0.0%	0.58%	+41.7%
ZFGN	New	ZAFGEN INC	$5,404,000	–	275,000	+100.0%	0.58%	–
BDSI	Sell	BIODELIVERY SCIENCES INTL IN	$5,230,000	-38.1%	306,000	-56.3%	0.56%	-32.2%
TRVN		TREVENA INC	$4,943,000	+13.6%	770,000	0.0%	0.53%	+24.4%
PCYC	New	PHARMACYCLICS INC	$4,697,000	–	40,000	+100.0%	0.50%	–
MGNX	Sell	MACROGENICS INC	$4,466,000	-52.4%	213,703	-50.5%	0.48%	-47.9%
THC	New	TENET HEALTHCARE CORP	$4,009,000	–	67,500	+100.0%	0.43%	–
THOR	New	THORATEC CORP	$3,943,000	–	147,501	+100.0%	0.42%	–
SPNC	Sell	SPECTRANETICS CORP	$3,677,000	-34.0%	138,371	-43.1%	0.40%	-27.7%
B108PS	New	ACTAVIS PLC	$3,619,000	–	15,000	+100.0%	0.39%	–
CMRX	Sell	CHIMERIX INC	$3,535,000	+9.1%	128,000	-13.5%	0.38%	+19.5%
ASTM	New	AASTROM BIOSCIENCES INC	$3,135,000	–	1,100,000	+100.0%	0.34%	–
WAG	Sell	WALGREEN CO	$2,964,000	-85.8%	50,000	-82.3%	0.32%	-84.5%
PFNX	New	PFENEX INC	$2,944,000	–	400,000	+100.0%	0.32%	–
SNSS	New	SUNESIS PHARMACEUTICALS INCcall	$2,856,000	–	400,000	+100.0%	0.31%	–
SNSS	New	SUNESIS PHARMACEUTICALS INCput	$2,856,000	–	400,000	+100.0%	0.31%	–
KERX	New	KERYX BIOPHARMACEUTICALSput	$2,750,000	–	200,000	+100.0%	0.30%	–
ARNI	New	ARNO THERAPEUTICS	$2,746,000	–	2,034,721	+100.0%	0.30%	–
TKAI	New	TOKAI PHARMACEUTICALS INC	$2,725,000	–	180,000	+100.0%	0.29%	–
PBYI	New	PUMA BIOTECHNOLOGY INC	$2,624,000	–	11,000	+100.0%	0.28%	–
ASPX	New	AUSPEX PHARMACEUTICALS INC	$2,567,000	–	100,000	+100.0%	0.28%	–
QTNT	Sell	QUOTIENT LTD	$2,493,000	-0.2%	263,844	-12.1%	0.27%	+9.4%
	New	CATALYST PHARM PARTNERS INC	$2,490,000	–	750,000	+100.0%	0.27%	–
LJPC	New	LA JOLLA PHARMACEUTICAL CO	$2,403,000	–	250,000	+100.0%	0.26%	–
MYL	Sell	MYLAN INC	$2,275,000	-84.4%	50,000	-82.3%	0.24%	-82.9%
MGCD	Buy	MGC DIAGNOSTICS CORP	$2,227,000	-16.0%	327,488	+3.5%	0.24%	-8.1%
ARDX	New	ARDELYX INC	$2,175,000	–	153,077	+100.0%	0.23%	–
ACST	Buy	ACASTI PHARMA INC	$1,982,000	-18.7%	2,573,645	+0.3%	0.21%	-10.9%
DSCI	Sell	DERMA SCIENCES INC	$1,798,000	-61.7%	215,809	-46.9%	0.19%	-58.1%
FPRX		FIVE PRIME THERAPEUTICS INC	$1,760,000	-24.6%	150,000	0.0%	0.19%	-17.5%
UPI	Buy	UROPLASTY INC	$1,743,000	-2.7%	697,287	+4.3%	0.19%	+6.2%
PRQR	New	PROQR THRAPEUTICS N V	$1,719,000	–	100,000	+100.0%	0.18%	–
GNVC		GENVEC INC	$1,706,000	-19.0%	820,000	0.0%	0.18%	-11.6%
ACHN	Sell	ACHILLION PHARMACEUTICALS IN	$1,697,000	-20.0%	170,000	-39.3%	0.18%	-12.5%
HIIQ	New	HEALTH INS INNOVATIONS INC	$1,591,000	–	131,025	+100.0%	0.17%	–
ELOS	Buy	SYNERON MEDICAL LTD	$1,503,000	+26.6%	150,000	+30.4%	0.16%	+38.8%
CLVS	Buy	CLOVIS ONCOLOGY INC	$1,402,000	+210.2%	30,917	+183.2%	0.15%	+243.2%
DRRX		DURECT CORP	$1,333,000	-19.3%	907,064	0.0%	0.14%	-11.7%
PARNF	New	PARNELL PHARMACEUT HLDGS LTD	$1,208,000	–	210,000	+100.0%	0.13%	–
CSBR		CHAMPIONS ONCOLOGY	$1,203,000	-26.0%	1,625,744	0.0%	0.13%	-18.9%
MNKD	New	MANNKIND CORPput	$1,182,000	–	200,000	+100.0%	0.13%	–
SNN	Sell	SMITH & NEPHEW PLCspdn adr new	$1,091,000	-46.8%	12,963	-43.5%	0.12%	-41.8%
ANTH	New	ANTHERA PHARMACEUTICALS INC	$919,000	–	478,456	+100.0%	0.10%	–
AQXP		AQUINOX PHARMACEUTICALS INC	$866,000	-28.9%	130,000	0.0%	0.09%	-21.8%
TBIO		TRANSGENOMIC INC	$692,000	+0.7%	183,957	0.0%	0.07%	+10.4%
GLMD		GALMED PHARMACEUTICALS LTD	$645,000	-11.8%	75,000	0.0%	0.07%	-4.2%
ABMD	New	ABIOMED INC	$621,000	–	25,000	+100.0%	0.07%	–
BOTA		BIOTA PHARMACEUTIALS INC	$626,000	-13.3%	253,400	0.0%	0.07%	-5.6%
ONTY	Buy	ONCOTHYREON INC	$624,000	-34.2%	325,000	+11.0%	0.07%	-28.0%
THLD	New	THRESHOLD PHARMACEUTICAL INC	$578,000	–	160,000	+100.0%	0.06%	–
AKAOQ		ACHAOGEN INC	$538,000	-35.8%	60,000	0.0%	0.06%	-29.3%
MDGN		MEDGENICS INC	$286,000	-33.2%	55,073	0.0%	0.03%	-26.2%
OXGN	Sell	OXIGENE INC	$266,000	-72.9%	123,518	-67.4%	0.03%	-69.8%
NXTM	New	NXSTAGE MEDICAL INC	$263,000	–	20,000	+100.0%	0.03%	–
PTX	New	PERNIX THERAPEUTICS INCcall	$192,000	–	25,000	+100.0%	0.02%	–
ICLR		ICON PLC	$140,000	+21.7%	2,440	0.0%	0.02%	+36.4%
CBPO		CHINA BIOLOGIC PRODS INC	$130,000	+21.5%	2,400	0.0%	0.01%	+40.0%
AMN	New	AMN HEALTHCARE SERVICES INC	$123,000	–	7,855	+100.0%	0.01%	–
AMSG	Buy	AMSURG CORP	$118,000	+31.1%	2,348	+18.6%	0.01%	+44.4%
ENTA	New	ENANTA PHARMACEUTICALS INC	$120,000	–	3,040	+100.0%	0.01%	–
GTIV		GENTIVA HEALTH SERVICES INC	$118,000	+11.3%	7,052	0.0%	0.01%	+30.0%
MGLN	Buy	MAGELLAN HEALTH INC	$120,000	+17.6%	2,189	+33.3%	0.01%	+30.0%
PRSC	New	PROVIDENCE SVC CORP	$122,000	–	2,532	+100.0%	0.01%	–
GTS		TRIPLE-S MGMT CORPcl b	$117,000	+11.4%	5,880	0.0%	0.01%	+30.0%
UHS	Sell	UNIVERSAL HLTH SVCS INCcl b	$115,000	-46.3%	1,101	-50.8%	0.01%	-42.9%
SMA		SYMMETRY MED INC	$112,000	+13.1%	11,148	0.0%	0.01%	+20.0%
V107SC	New	WELLPOINT INC	$108,000	–	901	+100.0%	0.01%	–
SEM	New	SELECT MED HLDGS CORP	$108,000	–	9,016	+100.0%	0.01%	–
SCLN	New	SCICLONE PHARMACEUTICALS INC	$110,000	–	16,035	+100.0%	0.01%	–
HRC	New	HILL ROM HLDGS INC	$110,000	–	2,657	+100.0%	0.01%	–
CYH	New	COMMUNITY HEALTH SYS INC NEW	$116,000	–	2,123	+100.0%	0.01%	–
CRL		CHARLES RIV LABS INTL INC	$111,000	+11.0%	1,860	0.0%	0.01%	+20.0%
CNC	Sell	CENTENE CORP DEL	$111,000	-97.6%	1,336	-97.8%	0.01%	-97.3%
AET	Sell	AETNA INC NEW	$106,000	-99.0%	1,308	-99.0%	0.01%	-98.9%
GB	New	GREATBATCH INC	$104,000	–	2,444	+100.0%	0.01%	–
EXAC		EXACTECH INC	$102,000	-9.7%	4,464	0.0%	0.01%	0.0%
MCK	Sell	MCKESSON CORP	$103,000	+4.0%	527	-0.6%	0.01%	+10.0%
LGND	Sell	LIGAND PHARMACEUTICALS INC	$105,000	-93.9%	2,245	-91.9%	0.01%	-93.5%
MRGE		MERGE HEALTHCARE INC	$96,000	-3.0%	43,478	0.0%	0.01%	0.0%
PDLI		PDL BIOPHARMA INC	$76,000	-23.2%	10,183	0.0%	0.01%	-20.0%
AIQ	New	ALLIANCE HEALTHCARE SRVCS IN	$79,000	–	3,500	+100.0%	0.01%	–
ICEL	New	CELLULAR DYNAMICS INTL INC	$1,000	–	164	+100.0%	0.00%	–
BSTC	Exit	BIOSPECIFICS TECHNOLOGIES CO	$0	–	-3,700	-100.0%	-0.01%	–
WCG	Exit	WELLCARE HEALTH PLANS INC	$0	–	-1,302	-100.0%	-0.01%	–
AFAM	Exit	ALMOST FAMILY INC	$0	–	-4,708	-100.0%	-0.01%	–
MDAS	Exit	MEDASSETS INC	$0	–	-4,429	-100.0%	-0.01%	–
Q	Exit	QUINTILES TRANSNATIO HLDGS I	$0	–	-1,875	-100.0%	-0.01%	–
PMC	Exit	PHARMERICA CORP	$0	–	-3,441	-100.0%	-0.01%	–
BCR	Exit	BARD C R INC	$0	–	-676	-100.0%	-0.01%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-2,380	-100.0%	-0.01%	–
HUM	Exit	HUMANA INC	$0	–	-803	-100.0%	-0.01%	–
ENSG	Exit	ENSIGN GROUP INC	$0	–	-3,509	-100.0%	-0.01%	–
SSH	Exit	SUNSHINE HEART INC	$0	–	-25,000	-100.0%	-0.01%	–
RDNT	Exit	RADNET INC	$0	–	-22,975	-100.0%	-0.02%	–
ARNA	Exit	ARENA PHARMACEUTICALS INCput	$0	–	-30,000	-100.0%	-0.02%	–
HNT	Exit	HEALTH NET INC	$0	–	-6,025	-100.0%	-0.02%	–
BLRX	Exit	BIOLINERX LTDsponsored adr	$0	–	-165,698	-100.0%	-0.03%	–
STEM	Exit	STEMCELLS INC	$0	–	-271,600	-100.0%	-0.05%	–
ICAD	Exit	ICAD INC	$0	–	-150,000	-100.0%	-0.09%	–
ATHX	Exit	ATHERSYS INC	$0	–	-601,852	-100.0%	-0.11%	–
INCY	Exit	INCYTE CORP	$0	–	-20,000	-100.0%	-0.11%	–
NLNK	Exit	NEWLINK GENETICS CORPcall	$0	–	-50,000	-100.0%	-0.13%	–
EXEL	Exit	EXELIXIS INCcall	$0	–	-400,000	-100.0%	-0.13%	–
OREX	Exit	OREXIGEN THERAPEUTICS INC	$0	–	-224,000	-100.0%	-0.14%	–
	Exit	ANTHERA PHARMACEUTICALS INC	$0	–	-478,456	-100.0%	-0.16%	–
KPTI	Exit	KARYOPHARM THERAPEUTICS INC	$0	–	-45,643	-100.0%	-0.21%	–
F113PS	Exit	COVIDIEN PLC	$0	–	-25,000	-100.0%	-0.22%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INCput	$0	–	-30,000	-100.0%	-0.28%	–
ZLTQ	Exit	ZELTIQ AESTHETICS INC	$0	–	-201,628	-100.0%	-0.30%	–
TSRO	Exit	TESARO INCput	$0	–	-100,000	-100.0%	-0.30%	–
AEGR	Exit	AEGERION PHARMACEUTICALS ORDcall	$0	–	-100,000	-100.0%	-0.32%	–
	Exit	ARNO THERAPEUTICS	$0	–	-2,034,721	-100.0%	-0.36%	–
WAG	Exit	WALGREEN COcall	$0	–	-50,000	-100.0%	-0.36%	–
CPRX	Exit	CATALYST PHARM PARTNERS INC	$0	–	-1,500,000	-100.0%	-0.37%	–
ICPT	Exit	INTERCEPT INCput	$0	–	-20,000	-100.0%	-0.46%	–
RGDO	Exit	REGADO BIOSCIENCES INC	$0	–	-860,000	-100.0%	-0.57%	–
MDT	Exit	MEDTRONIC INC	$0	–	-130,000	-100.0%	-0.81%	–
ITMN	Exit	INTERMUNE INC	$0	–	-210,000	-100.0%	-0.91%	–
ANAC	Exit	ANACOR PHARMACEUTICALS INC	$0	–	-528,776	-100.0%	-0.92%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-901,250	-100.0%	-1.51%	–
SHPG	Exit	SHIRE PLCsponsored adr	$0	–	-90,000	-100.0%	-2.08%	–
QCOR	Exit	QUESTCOR PHARMACEUTICALS INC	$0	–	-400,000	-100.0%	-3.63%	–

Original filings

The following EDGAR filing(s) were analyzed to create this report:

View 13F-HR/A filed 2014-11-17

Signatures

The EDGAR filing(s) were signed by:

Joseph Edelman — Managing Member

About Perceptive Advisors

Perceptive Advisors is a New York-based hedge fund that specializes in healthcare investments. The company was founded in 1999 by Joseph Edelman, who serves as the CEO and Chief Investment Officer. Since its inception, Perceptive Advisors has become one of the most successful healthcare-focused hedge funds in the world, with over $5 billion in assets under management.

The company's investment strategy is based on a deep understanding of the healthcare industry and a focus on identifying promising companies with innovative products and technologies. Perceptive Advisors invests in a wide range of healthcare sectors, including biotechnology, pharmaceuticals, medical devices, and healthcare services.

One of the key factors behind Perceptive Advisors' success is its team of experienced professionals. In addition to Joseph Edelman, the company's leadership team includes Adam Stone, the COO, and Jeremy Goldberg, the Chief Scientific Officer. The team also includes a group of highly skilled analysts and researchers who are experts in their respective fields.

Perceptive Advisors has a strong track record of generating high returns for its investors. However, it is important to note that investing in hedge funds carries significant risks, and investors should carefully consider their investment objectives and risk tolerance before investing. As with any investment, it is important to conduct thorough research and seek the advice of a qualified financial advisor before making any investment decisions.

It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.

Top long-term holdings

Name	Quarters owned	Latest quarter owned	Max weighting
NEUROCRINE BIOSCIENCES SHARES	42	Q3 2023	15.7%
AMICUS THERAPEUTICS SHARES	39	Q3 2023	14.0%
ALDEYRA THERAPEUTICS SHARES	35	Q3 2023	3.3%
QUOTIENT TECHNOLOGY INC	34	Q3 2022	2.7%
GLOBAL BLOOD THERAPEUTICS SHARES	29	Q3 2022	9.3%
ADMA BIOLOGICS SHARES	29	Q3 2023	1.4%
RETROPHIN SHARES	28	Q3 2020	5.5%
DBV TECHNOLOGIES SA-SPON ADR	28	Q3 2021	1.8%
VBI VACCINES SHARES	27	Q1 2023	2.8%
IOVANCE BIOTHERAPEUTICS INC	26	Q3 2023	9.1%

View Perceptive Advisors's complete holdings history.

Latest significant ownerships (13-D/G)

Perceptive Advisors Q3 2014 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
	Filed	Shares	Percentage
CHEMBIO DIAGNOSTICS, INC.^{Sold out}	May 04, 2023	0	0.0%
VBI Vaccines Inc/BC	April 07, 2023	43,509,553	16.7%
Landos Biopharma, Inc.	March 30, 2023	14,869,915	47.7%
REATA PHARMACEUTICALS INC	March 07, 2023	2,083,799	6.5%
AGILE THERAPEUTICS INC^{Sold out}	February 14, 2023	0	0.0%
ALBIREO PHARMA, INC.	February 14, 2023	1,757,160	8.5%
BELLUS Health Inc.	February 14, 2023	8,891,027	7.1%
CinCor Pharma, Inc.	February 14, 2023	2,576,325	5.9%
Coherus BioSciences, Inc.^{Sold out}	February 14, 2023	0	0.0%
CONCERT PHARMACEUTICALS, INC.	February 14, 2023	1,800,000	3.6%

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Latest filings

Type	Filed
4	2024-04-15
SC 13G/A	2024-04-15
SC 13G	2024-04-15
SC 13D/A	2024-04-10
4	2024-04-08
4	2024-04-03
SC 13D/A	2024-04-03
SC 13D	2024-03-20
SC 13G	2024-03-14
SC 13G	2024-03-11

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The following issues were detected while analyzing the report:

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The reported has been amended

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