Name,Ticker,Title of class,Class,Change,CUSIP,Value,Shares or principal amount,Weighting Moderna Inc,MRNA,,Sell,60770K107,16247771000.0,42217354.0,8.5 Tesla Inc,TSLA,,Sell,88160R101,10742820000.0,13853124.0,5.62 Illumina,ILMN,,Sell,452327109,8367188000.0,20628655.0,4.377 MercadoLibre,MELI,,Buy,58733R102,7897064000.0,4702313.0,4.132 Shopify Inc,SHOP,,Sell,82509L107,7449602000.0,5494689.0,3.897 Amazon.Com,AMZN,,Sell,023135106,7375168000.0,2245077.0,3.858 Spotify Technology SA,SPOT,,Buy,L8681T102,5032640000.0,22333544.0,2.633 Netflix Inc,NFLX,,Sell,64110L106,4873796000.0,7985380.0,2.55 NVIDIA,NVDA,,Buy,67066G104,4269338000.0,20608893.0,2.234 The Trade Desk,TTD,,Sell,88339J105,3661463000.0,52083406.0,1.916 Cloudflare Inc,NET,,Sell,18915M107,3349642000.0,29734942.0,1.752 NIO Inc ADR,NIO,spon ads,Sell,62914V106,3229040000.0,90627004.0,1.689 SEA Ltd ADR,SE,adr,Sell,81141R100,3071776000.0,9637552.0,1.607 Dexcom Inc,DXCM,,Buy,252131107,2925601000.0,5349818.0,1.531 Facebook Cl.A,FB,cl a,Sell,30303M102,2682743000.0,7904602.0,1.404 Wayfair Inc Class A,W,cl a,Sell,94419L101,2551764000.0,9986944.0,1.335 Pinduoduo Inc ADR,PDD,sponsored ads,Buy,722304102,2492383000.0,27488510.0,1.304 Peloton Interactive Inc,PTON,,Buy,70614W100,2453855000.0,28189031.0,1.284 Carvana,CVNA,,Sell,146869102,2327300000.0,7718043.0,1.218 Atlassian Corp Plc,TEAM,cl a,Sell,G06242104,2306463000.0,5892549.0,1.207 Workday Inc,WDAY,cl a,Sell,98138H101,2261817000.0,9051250.0,1.183 Ferrari NV,RACE,,Sell,N3167Y103,2133862000.0,10175203.0,1.116 Zoom Video Communications Inc,ZM,cl a,Sell,98980L101,2081294000.0,7959057.0,1.089 Alnylam Pharmaceuticals,ALNY,,Buy,02043Q107,1966605000.0,10415784.0,1.029 Moody's Corp,MCO,,Sell,615369105,1953125000.0,5500058.0,1.022 Microsoft,MSFT,,Sell,594918104,1952976000.0,6927412.0,1.022 Twilio Inc,TWLO,cl a,Buy,90138F102,1949128000.0,6109161.0,1.02 Alphabet Inc Class C,GOOG,cap stk cl c,Sell,02079K107,1803428000.0,676630.0,0.944 BioNTech ADR,BNTX,spons ads,Sell,09075V102,1732208000.0,6345313.0,0.906 BeiGene Ltd,BGNE,sponsored adr,Sell,07725L102,1542406000.0,4249052.0,0.807 Doordash Inc,DASH,,Buy,25809K105,1520075000.0,7379725.0,0.795 Intuitive Surgical,ISRG,,Sell,46120E602,1500861000.0,1509693.0,0.785 Anthem Inc,ANTM,,Sell,036752103,1489211000.0,3994663.0,0.779 Alibaba Group Holding Sponsored ADR,BABA,sponsored ads,Sell,01609W102,1477137000.0,9977288.0,0.773 Salesforce.com,CRM,,Sell,79466L302,1380816000.0,5091131.0,0.722 Coupang,CPNG,cl a,Buy,22266T109,1365081000.0,49015455.0,0.714 Affirm Holdings Inc Class B - converted at IPO,AFRM,,Sell,00827B106,1284676000.0,10783815.0,0.672 Martin Marietta Materials,MLM,,Sell,573284106,1282120000.0,3752401.0,0.671 Chegg,CHGG,,Sell,163092109,1258461000.0,18501345.0,0.658 Abiomed,ABMD,,Buy,003654100,1215397000.0,3733710.0,0.636 AJ Gallagher & Co,AJG,,Sell,363576109,1200725000.0,8077529.0,0.628 Snowflake Inc,SNOW,,Sell,833445109,1195722000.0,3953719.0,0.626 Ryanair ADR,RYAAY,sponsored adr ne,Buy,783513203,1186170000.0,10777474.0,0.621 Roku,ROKU,,Sell,77543R102,1144808000.0,3653449.0,0.599 Mastercard Inc-Class A,MA,cl a,Sell,57636Q104,1127488000.0,3242893.0,0.59 Teladoc,TDOC,,Buy,87918A105,1116602000.0,8805307.0,0.584 Novocure Ltd,NVCR,,Buy,G6674U108,1088478000.0,9369705.0,0.569 Service Corp.Intl.,SCI,,Buy,817565104,1086738000.0,18034142.0,0.569 Cbre Group Inc,CBRE,cl a,Sell,12504L109,1082769000.0,11121281.0,0.566 CoStar Group,CSGP,,Buy,22160N109,1078933000.0,12536980.0,0.564 Ginkgo Bioworks Holdings Inc,,,New,37611X100,1054722000.0,91002810.0,0.552 Albemarle Corp,ALB,,Sell,012653101,1002226000.0,4577000.0,0.524 Petrobras Common ADR,PBR,sponsored adr,Buy,71654V408,990270000.0,95770837.0,0.518 First Republic Bank,FRC,,Sell,33616C100,948198000.0,4915997.0,0.496 Datadog,DDOG,,Sell,23804L103,942402000.0,6667148.0,0.493 Estee Lauder 'A',EL,,Sell,518439104,915221000.0,3051450.0,0.479 Beyond Meat Inc,BYND,,Buy,08862E109,900948000.0,8559271.0,0.471 Thermo Fisher Scientific,TMO,,Sell,883556102,855433000.0,1497266.0,0.448 TSMC ADR,TSM,sponsored adr,Sell,874039100,827168000.0,7408578.0,0.433 Booking Holdings Inc,BKNG,,Sell,09857L108,816034000.0,343757.0,0.427 10X Genomics Inc Class A,TXG,,Buy,88025U109,806896000.0,5542625.0,0.422 S&P Global Inc,SPGI,,Sell,78409V104,802463000.0,1888638.0,0.42 Axon Enterprise Inc,AXON,,Buy,05464C101,794355000.0,4538658.0,0.416 Teradyne,TER,,Sell,880770102,790748000.0,7243278.0,0.414 Zillow Group Inc Class C,Z,cl c cap stk,Buy,98954M200,757783000.0,8597495.0,0.396 Mettler-Toledo,MTD,,Buy,592688105,757186000.0,549737.0,0.396 Denali Therapeutics,DNLI,,Sell,24823R105,757245000.0,15009816.0,0.396 ResMed,RMD,,Sell,761152107,751154000.0,2850142.0,0.393 SiteOne Landscape Supply,SITE,,Sell,82982L103,745801000.0,3738911.0,0.39 MarketAxess Holdings,MKTX,,Sell,57060D108,738107000.0,1754514.0,0.386 Staar Surgical,STAA,,Sell,852312305,702290000.0,5464019.0,0.367 Broadridge Finl.Sltn.,BR,,Sell,11133T103,680343000.0,4082706.0,0.356 Wix Com,WIX,,Sell,M98068105,651860000.0,3326322.0,0.341 ICICI Bank ADR,IBN,adr,Buy,45104G104,619758000.0,32843613.0,0.324 Baidu.com Sponsored ADR,BIDU,spon adr rep a,Sell,056752108,590804000.0,3842624.0,0.309 Appian Corp,APPN,cl a,Sell,03782L101,569536000.0,6156470.0,0.298 Farfetch,FTCH,,Buy,30744W107,562827000.0,15016724.0,0.294 Watsco Inc,WSO,,Sell,942622200,540395000.0,2042156.0,0.283 Chewy Inc,CHWY,cl a,Sell,16679L109,534475000.0,7847239.0,0.28 Coursera Inc,COUR,,Buy,22266M104,532344000.0,16819718.0,0.279 Redfin,RDFN,,Sell,75737F108,520689000.0,10392986.0,0.272 Zai Lab ADR,ZLAB,adr,Buy,98887Q104,515914000.0,4895281.0,0.27 Recursion Pharmaceuticals Inc,RXRX,cl a,Buy,75629V104,507632000.0,22061374.0,0.266 Markel Corp,MKL,,Sell,570535104,502887000.0,420780.0,0.263 Exact Sciences,EXAS,,Sell,30063P105,424994000.0,4452527.0,0.222 Certara,CERT,,Buy,15687V109,418815000.0,12653015.0,0.219 Lyft Inc Class A Common,LYFT,,Sell,55087P104,406993000.0,7594572.0,0.213 Li Auto ADR,LI,spons ads,Sell,50202M102,389005000.0,14796649.0,0.204 Snap Inc,SNAP,cl a,Sell,83304A106,386438000.0,5231335.0,0.202 KE Holdings ADR,BEKE,adr,Sell,482497104,380480000.0,20836776.0,0.199 Copa Holdings S A,CPA,cl a,Sell,P31076105,379289000.0,4660727.0,0.198 Tencent Music Entertainment ADR,TME,sponsored ads,Buy,88034P109,368412000.0,50815363.0,0.193 Oatly Inc.,OTLY,spons ads,Sell,67421J108,358366000.0,23701426.0,0.187 Penumbra Inc,PEN,,Sell,70975L107,352778000.0,1323744.0,0.185 Full Truck Alliance - converted at IPO,YMM,spons ads,Sell,35969L108,342389000.0,141256527.0,0.179 Lemonade Inc,LMND,,Sell,52567D107,337038000.0,5029676.0,0.176 Pinterest,PINS,,Sell,72352L106,334452000.0,6564308.0,0.175 Deere & Co,DE,,Buy,244199105,334939000.0,999611.0,0.175 Zillow Group Inc Class A,ZG,cl a,Sell,98954M101,322167000.0,3637015.0,0.169 Stericycle Inc,SRCL,,Sell,858912108,323814000.0,4764058.0,0.169 Howard Hughes,HHC,,Sell,44267D107,302347000.0,3443194.0,0.158 Cemex ADR,CX,spon adr new,Buy,151290889,299033000.0,41706111.0,0.156 Xylem,XYL,,Buy,98419M100,280155000.0,2265161.0,0.147 Upwork Inc,UPWK,,Buy,91688F104,270452000.0,6006014.0,0.141 Itau Unibanco Holding SA-ADR,ITUB,spon adr rep pfd,Sell,465562106,265146000.0,50312410.0,0.139 Warby Parker Inc,,,New,93403J106,264771000.0,4990973.0,0.139 Vroom Inc,VRM,,Sell,92918V109,261207000.0,11835357.0,0.137 Sana Biotechnology Inc,SANA,,Sell,799566104,251995000.0,11189832.0,0.132 Oscar Health Inc,OSCR,,Buy,687793109,251993000.0,14490597.0,0.132 Vimeo Inc.,VMEO,,Buy,92719V100,228335000.0,7774424.0,0.119 Iac/Interactivecorp,IAC,,Sell,44891N208,223590000.0,1716091.0,0.117 CureVac N.V. - Converted at IPO,CVAC,,Sell,N2451R105,215243000.0,3940731.0,0.113 Duolingo Inc,,,New,26603R106,210522000.0,1265457.0,0.11 Tata Motors Ltd ADR,TTM,,Buy,876568502,201690000.0,9000004.0,0.106 Vale SA ADR,VALE,adr,Sell,91912E105,196014000.0,14051128.0,0.103 Credicorp,BAP,,Sell,G2519Y108,189151000.0,1704990.0,0.099 Ecolab,ECL,,Buy,278865100,187676000.0,899609.0,0.098 Lilium NV,,,New,N52586109,186084000.0,17705415.0,0.097 LendingTree,TREE,,Sell,52603B107,183166000.0,1309917.0,0.096 Kingsoft Cloud Holdings Ltd ADR,KC,spon adr,Sell,49639K101,180171000.0,6361989.0,0.094 Jumia Technologies Ag ADR,JMIA,sponsored ads,Sell,48138M105,176399000.0,9488902.0,0.092 Vir Biotechnology Inc,VIR,,Buy,92764N102,169715000.0,3899692.0,0.089 Ritchie Bros Auctioneers (USA),RBA,,Sell,767744105,168107000.0,2725732.0,0.088 HDFC Bank ADR,HDB,,Buy,40415F101,169015000.0,2312431.0,0.088 Blackline,BL,,Sell,09239B109,160255000.0,1357403.0,0.084 Burning Rock Biotech Ltd ADR,BNR,spon ads,Buy,12233L107,157204000.0,8792152.0,0.082 Petrobras Pref ADR,PBRA,sp adr non vtg,Buy,71654V101,154454000.0,15445510.0,0.081 Codexis,CDXS,,Sell,192005106,153953000.0,6618823.0,0.081 Banco Bradesco Pn ADR,BBD,sp adr pfd new,Sell,059460303,154226000.0,40267672.0,0.081 Alphabet Inc Class A,GOOGL,cap stk cl a,Sell,02079K305,152040000.0,56869.0,0.08 Dada Nexus Ltd ADR,DADA,ads,Sell,23344D108,151644000.0,7567092.0,0.079 Autohome Inc - ADR,ATHM,sp adr rp cl a,Sell,05278C107,139851000.0,2979984.0,0.073 Lufax Holding Ltd,LU,,Buy,54975P102,137393000.0,19683818.0,0.072 JD.Com Inc - ADR,JD,spon adr cl a,Sell,47215P106,126249000.0,1747619.0,0.066 ShockWave Medical Inc,SWAV,,Buy,82489T104,121220000.0,588789.0,0.063 Fastenal,FAST,,Sell,311900104,120244000.0,2329857.0,0.063 Pacira BioSciences,PCRX,,Sell,695127100,116917000.0,2087807.0,0.061 Everbridge Inc,EVBG,,Sell,29978A104,117224000.0,776119.0,0.061 Trupanion,TRUP,,Sell,898202106,110415000.0,1421595.0,0.058 Ares Capital Corp,ARCC,,Sell,04010L103,108529000.0,5338370.0,0.057 TAL Education Group ADR,TAL,,Sell,874080104,106799000.0,22065841.0,0.056 CyberArk Software Ltd,CYBR,,Sell,M2682V108,105437000.0,668086.0,0.055 Ozon Holdings,OZON,,Buy,69269L104,104010000.0,2061643.0,0.054 Trip.com Group Sponsored ADR,TCOM,,Sell,89677Q107,101295000.0,3294152.0,0.053 Glaukos Corp,GKOS,,Sell,377322102,97319000.0,2020325.0,0.051 United Parcel Service,UPS,cl b,Sell,911312106,96407000.0,529418.0,0.05 Sprout Social,SPT,,Sell,85209W109,94537000.0,775212.0,0.049 ChargePoint Holdings Inc,CHPT,,Buy,15961R105,91580000.0,4581274.0,0.048 Futu Hdgs ADR,FUTU,spon adr cl a,New,36118L106,92549000.0,1016800.0,0.048 Ambarella,AMBA,,Sell,G037AX101,88883000.0,570719.0,0.047 Procter & Gamble,PG,,Buy,742718109,83433000.0,596802.0,0.044 Rubius Therapeutics Inc,RUBY,,Sell,78116T103,83927000.0,4693832.0,0.044 Aerovironment,AVAV,,Sell,008073108,78404000.0,908296.0,0.041 Joby Aviation Inc,,,New,G65163100,77233000.0,7677200.0,0.04 Avangrid,AGR,,Buy,05351W103,74095000.0,1524614.0,0.039 LivePerson Inc,LPSN,,Sell,538146101,74985000.0,1272007.0,0.039 Prologis Inc REIT,PLD,,Sell,74340W103,72792000.0,580341.0,0.038 Duke Realty Corporation REIT,DRE,,Sell,264411505,68654000.0,1434182.0,0.036 iRobot,IRBT,,Sell,462726100,67978000.0,865948.0,0.036 Adaptimmune Therapeutics ADR,ADAP,sponds adr,Buy,00653A107,66306000.0,12824980.0,0.035 First Industrial REIT,FR,,Sell,32054K103,67371000.0,1293601.0,0.035 MakeMyTrip,MMYT,,Sell,V5633W109,66962000.0,2462730.0,0.035 Infosys Ltd ADR,INFY,sponsored adr,Buy,456788108,67023000.0,3012266.0,0.035 Rexford Industrial Realty REIT,REXR,,Sell,76169C100,67270000.0,1185373.0,0.035 Pepsico,PEP,,Sell,713448108,67735000.0,450336.0,0.035 Liveramp Holdings Inc,RAMP,,Sell,53815P108,64794000.0,1371902.0,0.034 Abcellera Biologics Inc,ABCL,,Buy,00288U106,64940000.0,3240543.0,0.034 Zuora Inc Class A,ZUO,,Sell,98983V106,65060000.0,3924037.0,0.034 NextEra Energy,NEE,,Buy,65339F101,62393000.0,794623.0,0.033 HUYA ADR,HUYA,,Sell,44852D108,63657000.0,7632744.0,0.033 Cardlytics Inc,CDLX,,Buy,14161W105,62602000.0,745804.0,0.033 Bilibili Inc ADR,BILI,sponsored adr,Sell,090040106,63545000.0,960316.0,0.033 Vedanta Ltd ADR,VEDL,,Buy,92242Y100,63913000.0,4182806.0,0.033 Apple,AAPL,,Buy,037833100,60531000.0,427782.0,0.032 Analog Devices,ADI,,Buy,032654105,59289000.0,354010.0,0.031 IPG Photonics Corp,IPGP,,Sell,44980X109,58890000.0,371784.0,0.031 iShares Physical Silver ETC (c),SLV,,Buy,46428Q109,59384000.0,2787200.0,0.031 Consolidated Edison,ED,,Buy,209115104,56719000.0,781352.0,0.03 Q2 Holdings Inc,QTWO,,Sell,74736L109,56798000.0,708740.0,0.03 Berkeley Lights Inc,BLI,,Buy,084310101,57429000.0,2936034.0,0.03 Splunk Inc,SPLK,,Sell,848637104,53842000.0,372070.0,0.028 DTE Energy Co,DTE,,Sell,233331107,50931000.0,455921.0,0.027 StoneCo Brazil DR,STNE,,Buy,G85158106,52213000.0,1503801.0,0.027 CH Robinson Worldwide,CHRW,,Buy,12541W209,52317000.0,601340.0,0.027 American Electric Power,AEP,,Sell,025537101,50280000.0,619364.0,0.026 Eversource Energy,ES,,Buy,30040W108,46924000.0,573935.0,0.025 Edwards Lifesciences Corp,EW,,Buy,28176E108,47723000.0,421545.0,0.025 Coca Cola,KO,,Sell,191216100,45422000.0,865671.0,0.024 Ameren,AEE,,Sell,023608102,46467000.0,573649.0,0.024 Yatsen Holding Ltd ADR,YSG,,Buy,985194109,46385000.0,12174391.0,0.024 Silicon Motion Technology ADR,SIMO,,Buy,82706C108,44955000.0,651703.0,0.024 Brookfield Renewable,BEPC,,Buy,11284V105,43976000.0,1133120.0,0.023 JFrog Ltd,FROG,,Sell,M6191J100,43300000.0,1292523.0,0.023 dLocal,DLO,cl a, ,G29018101,43648000.0,800000.0,0.023 Tandem Diabetes Care,TNDM,,Buy,875372203,41430000.0,347052.0,0.022 National Instruments Corp,NATI,,Buy,636518102,41284000.0,1052367.0,0.022 T. Rowe Price,TROW,,Buy,74144T108,39470000.0,200656.0,0.021 Medtronic,MDT,,Buy,G5960L103,39294000.0,313480.0,0.021 Clear Secure Inc,YOU,, ,18467V109,41050000.0,1000000.0,0.021 McDonald's,MCD,,Sell,580135101,40774000.0,169107.0,0.021 Cisco Systems,CSCO,,Buy,17275R102,37423000.0,687555.0,0.02 Clover Health Investments Corp,CLOV,, ,18914F103,38001000.0,5142177.0,0.02 Zymergen Inc - converted at IPO,ZY,, ,98985X100,37165000.0,2821956.0,0.019 Sutro Biopharma,STRO,,Buy,869367102,33906000.0,1794940.0,0.018 Starbucks Corp,SBUX,,New,855244109,32924000.0,298468.0,0.017 Quanterix Corp,QTRX,,Buy,74766Q101,29952000.0,601558.0,0.016 Iclick Interactive Asia G,ICLK,spon adr,Buy,45113Y104,29458000.0,5326887.0,0.015 Cullen/Frost Bankers,CFR,,Buy,229899109,29147000.0,245722.0,0.015 Digimarc,DMRC,,Sell,25381B101,28468000.0,826584.0,0.015 Veeco Instruments,VECO,,Sell,922417100,29203000.0,1314844.0,0.015 Dolby Laboratories 'A',DLB,,Buy,25659T107,27465000.0,312104.0,0.014 Baozun Spn Adr 1:1,BZUN,sponsored adr,Sell,06684L103,26319000.0,1501340.0,0.014 Tabula Rasa HealthCare Inc,TRHC,,Sell,873379101,27507000.0,1049499.0,0.014 Waters,WAT,,Buy,941848103,25059000.0,70133.0,0.013 EverQuote Inc,EVER,,Sell,30041R108,24957000.0,1339621.0,0.013 QuantumScape Corp,QS,,Buy,74767V109,22481000.0,916109.0,0.012 Masimo Corp,MASI,,Buy,574795100,23381000.0,86368.0,0.012 Golub Capital BDC Inc,GBDC,,New,38173M102,22329000.0,1412330.0,0.012 MELI Kaszek Pioneer,,,New,G5S74L106,22100000.0,2000000.0,0.012 Butterfly Network Inc,BFLY,,Buy,124155102,21036000.0,2015008.0,0.011 CEVA Inc,CEVA,,Sell,157210105,20458000.0,479464.0,0.011 American Superconductor Corp,AMSC,,Buy,030111207,21744000.0,1491370.0,0.011 BridgeBio Pharma Inc,BBIO,,Buy,10806X102,21835000.0,465876.0,0.011 Agora Inc ADR,API,ads, ,00851L103,21584000.0,744300.0,0.011 NetEase.com ADR,NTES,sponsored adr,Sell,64110W102,21523000.0,252028.0,0.011 FirstCash,FCFS,,Sell,33767D105,18776000.0,214587.0,0.01 Bumble Inc,BMBL,, ,12047B105,19992000.0,400000.0,0.01 Health Catalyst Inc,HCAT,,Buy,42225T107,19054000.0,381003.0,0.01 Stratasys,SSYS,,Sell,M85548101,18816000.0,874383.0,0.01 Axogen Inc,AXGN,,Sell,05463X106,18354000.0,1161659.0,0.01 Royal Caribbean Cruises,RCL,,Sell,V7780T103,16753000.0,188339.0,0.009 Six Flags Entertainment Corp,SIX,,Sell,83001A102,16392000.0,385701.0,0.009 Align Technology Inc,ALGN,,Sell,016255101,16390000.0,24631.0,0.009 Nanobiotix ADR,NBTX,, ,63009J107,15862000.0,1400000.0,0.008 Sherwin-Williams Co,SHW,,Sell,824348106,12435000.0,44453.0,0.007 Hutchison China Meditech,HCM,sponsored adr,Buy,44842L103,13471000.0,367965.0,0.007 Cooper Cos Inc/The,COO,,Sell,216648402,12967000.0,31373.0,0.007 Ascendis Pharma ADR 1:1,ASND,spon adr,Buy,04351P101,13299000.0,83434.0,0.007 Cellectis ADR,CLLS,spons ads,Buy,15117K103,13574000.0,1076525.0,0.007 OneConnect Financial Technology ADR,OCFT,,Sell,68248T105,12190000.0,2973146.0,0.006 Veeva Systems Inc Class A,VEEV,,Buy,922475108,11087000.0,38471.0,0.006 Visa Inc-Class A Shares,V,,Sell,92826C839,11697000.0,52510.0,0.006 Burford Capital,BUR,,Buy,G17977110,11338000.0,1038109.0,0.006 Chinook Therapeutics,KDNY,,Sell,16961L106,10688000.0,837576.0,0.006 Dt Midstream Inc,DTM,,New,23345M107,10602000.0,229294.0,0.006 Spire Global Inc,,,New,848560108,10852000.0,866045.0,0.006 Nucana Plc ADR,NCNA,sponsored adr, ,67022C106,9441000.0,3659030.0,0.005 Docebo,,,Buy,25609L105,9886000.0,135418.0,0.005 Benefitfocus Inc,BNFT,,Sell,08180D106,10439000.0,940392.0,0.005 Ionis Pharmaceuticals,IONS,,Buy,462222100,10129000.0,302003.0,0.005 Verisk Analytics,VRSK,,Sell,92345Y106,10113000.0,50495.0,0.005 Relay Therapeutics Inc,RLAY,,Buy,75943R102,6718000.0,213089.0,0.004 Alector Inc,ALEC,,Buy,014442107,7767000.0,340352.0,0.004 British Amer.Tobacco - ADR,BTI,sponsored adr,Sell,110448107,6849000.0,194106.0,0.004 Fortive Corp,FTV,,Sell,34959J108,6903000.0,97814.0,0.004 Lyell Immunopharma Inc,LYEL,,Buy,55083R104,6327000.0,427483.0,0.003 TJX Companies,TJX,,Sell,872540109,5733000.0,86893.0,0.003 Sixth Street Specialty Lending,TSLX,,New,83012A109,5066000.0,228078.0,0.003 Uxin ADR,UXIN,ads, ,91818X108,4902000.0,1776100.0,0.003 Kaleido Biosciences Inc,KLDO,,Buy,483347100,3600000.0,659227.0,0.002 Sage Therapeutics Inc,SAGE,,Buy,78667J108,3824000.0,86298.0,0.002 American Well Corp Class A,AMWL,,Buy,03044L105,4578000.0,502551.0,0.002 Sohu.com,SOHU,, ,83410S108,4171000.0,200140.0,0.002 Exelon Corporation,EXC,, ,30161N101,1076000.0,22268.0,0.001 Korea Electric Power ADR,KEP,sponsored adr, ,500631106,1615000.0,163646.0,0.001 Unity Biotechnology Inc,UBX,,Sell,91381U101,1767000.0,589111.0,0.001 Saba Capital Income & Opportunities Fund,PPR,sh ben int,Sell,92913A100,1969000.0,432792.0,0.001 Newmont Mining,NEM,,Buy,651639106,1095000.0,20172.0,0.001 Fortis,FTS,, ,349553107,1351000.0,30457.0,0.001 Summit Therapeutics New Listing,SMMT,, ,86627T108,2187000.0,436512.0,0.001 WEC Energy Group,WEC,, ,92939U106,1344000.0,15233.0,0.001 Adicet Bio Inc,ACET,, ,007002108,1424000.0,181626.0,0.001 Blue Apron Holdings Inc,APRN,cl a, ,09523Q101,1092000.0,148506.0,0.001 Jackson Financial CDI,,,New,46817M107,986000.0,37907.0,0.001 Proofpoint Inc,PFPT,,Exit,743424103,0.0,-144.0,0.0 Acadia Pharmaceuticals Inc,ACAD,, ,004225108,9000.0,544.0,0.0 Accelerate Diagnostics,AXDX,, ,00430H102,2000.0,418.0,0.0 Acutus Medical,AFIB,, ,005111109,4000.0,424.0,0.0 Advanced Micro Devices Inc,AMD,,Sell,007903107,44000.0,428.0,0.0 Agios Pharmaceuticals Inc,AGIO,, ,00847X104,9000.0,186.0,0.0 Allscripts Healthcare Solution,MDRX,, ,01988P108,10000.0,744.0,0.0 Alteryx Inc,AYX,, ,02156B103,25000.0,336.0,0.0 American Tower Corp REIT,AMT,,New,03027X100,512000.0,1930.0,0.0 Amicus Therapeutics Inc,FOLD,, ,03152W109,5000.0,538.0,0.0 Amkor Technology,AMKR,,Sell,031652100,47000.0,1891.0,0.0 Amneal Pharmaceuticals Inc,AMRX,, ,03168L105,2000.0,452.0,0.0 Anaplan Inc Common,PLAN,, ,03272L108,19000.0,306.0,0.0 Anterix,ATEX,, ,03676C100,10000.0,162.0,0.0 AppFolio,APPF,,Sell,03783C100,29000.0,241.0,0.0 Argan,AGX,, ,04010E109,4000.0,103.0,0.0 Asensus Surgical Inc,ASXC,, ,04367G103,10000.0,5338.0,0.0 AstraZeneca ADR,AZN,,New,046353108,24000.0,400.0,0.0 Atrion,ATRI,, ,049904105,6000.0,9.0,0.0 Avery Dennison Corporation,AVY,, ,053611109,23000.0,110.0,0.0 Axonics Modulation Technologies,AXNX,, ,05465P101,15000.0,230.0,0.0 Bandwidth,BAND,,Buy,05988J103,41000.0,448.0,0.0 Beam Therapeutics,BEAM,,Buy,07373V105,931000.0,10700.0,0.0 BioCryst Pharmaceuticals,BCRX,,New,09058V103,22000.0,1500.0,0.0 Biomarin Pharmaceutical Inc,BMRN,, ,09061G101,6000.0,82.0,0.0 Research in Motion,BB,,Sell,09228F103,27000.0,2731.0,0.0 Blackrock Inc,BLK,, ,09247X101,18000.0,21.0,0.0 Blink Charging,BLNK,, ,09354A100,11000.0,400.0,0.0 Bluebird Bio Inc,BLUE,, ,09609G100,16000.0,860.0,0.0 Blueprint Medicines Corp,BPMC,,Sell,09627Y109,35000.0,343.0,0.0 Boston Omaha,BOMN,, ,101044105,21000.0,529.0,0.0 Box Inc,BOX,, ,10316T104,23000.0,979.0,0.0 Brady Corp,BRC,, ,104674106,12000.0,245.0,0.0 Bristol Myers Squibb,BMY,,Sell,110122108,28000.0,474.0,0.0 C3.ai,AI,cl a, ,12468P104,5000.0,117.0,0.0 CS Disco Inc,,,New,126327105,24000.0,504.0,0.0 Calavo Growers Inc,CVGW,, ,128246105,4000.0,113.0,0.0 Cargurus Inc,CARG,,Buy,141788109,38000.0,1190.0,0.0 Castle Biosciences,CSTL,,Buy,14843C105,15000.0,225.0,0.0 Celsius Holdings,CELH,, ,15118V207,23000.0,260.0,0.0 Cerus,CERS,, ,157085101,7000.0,1143.0,0.0 Church & Dwight Co Inc,CHD,, ,171340102,15000.0,179.0,0.0 Cloudera Inc,CLDR,,Sell,18914U100,7000.0,428.0,0.0 Cohen & Steers Inc,CNS,,Sell,19247A100,27000.0,325.0,0.0 Coherus BioSciences,CHRS,,Sell,19249H103,26000.0,1605.0,0.0 Cohu,COHU,,New,192576106,22000.0,700.0,0.0 Columbia Sportswear Co,COLM,, ,198516106,9000.0,95.0,0.0 Commscope Holding Co Inc,COMM,,Sell,20337X109,20000.0,1442.0,0.0 Cornerstone Ondemand Inc,CSOD,,Sell,21925Y103,48000.0,838.0,0.0 Costco Wholesale Corporation,COST,,Sell,22160K105,29000.0,65.0,0.0 Coupa Software Inc,COUP,,Sell,22266L106,71000.0,324.0,0.0 CrowdStrike Holdings,CRWD,,Sell,22788C105,31000.0,125.0,0.0 Darden Restaurants,DRI,, ,237194105,12000.0,82.0,0.0 DermTech,,, ,24984K105,9000.0,286.0,0.0 Domo,DOMO,,Sell,257554105,29000.0,348.0,0.0 Dropbox,DBX,cl a, ,26210C104,26000.0,881.0,0.0 Duck Creek Technologies,DCT,, ,264120106,16000.0,355.0,0.0 EHang Hdgs ADR,EH,ads,New,26853E102,50000.0,2100.0,0.0 Eargo,EAR,, ,270087109,2000.0,263.0,0.0 8x8 Inc,EGHT,,Sell,282914100,51000.0,2193.0,0.0 Emergent Biosolutions Inc,EBS,,Sell,29089Q105,19000.0,385.0,0.0 Enphase Energy Inc,ENPH,,New,29355A107,135000.0,900.0,0.0 Exelixis,EXEL,,New,30161Q104,25000.0,1200.0,0.0 Expedia Group Inc,EXPE,,New,30212P303,27000.0,165.0,0.0 Expeditors Intl,EXPD,, ,302130109,15000.0,126.0,0.0 Exponent,EXPO,, ,30214U102,27000.0,242.0,0.0 Fastly,FSLY,cl a, ,31188V100,8000.0,205.0,0.0 Fibrogen Inc,FGEN,, ,31572Q808,5000.0,467.0,0.0 First Majestic Silver,AG,, ,32076V103,92000.0,8100.0,0.0 Fox,FOXA,, ,35137L105,14000.0,359.0,0.0 Freshpet Inc,FRPT,,Buy,358039105,28000.0,196.0,0.0 Gentex Corp,GNTX,, ,371901109,17000.0,516.0,0.0 Global Blood Therapeutics Inc,GBT,,Sell,37890U108,21000.0,835.0,0.0 Goodyear Tire & Rubber Co/The,GT,,New,382550101,25000.0,1400.0,0.0 Graco,GGG,, ,384109104,25000.0,363.0,0.0 "Grainger, WW",GWW,,New,384802104,23000.0,59.0,0.0 Halozyme Therapeutics,HALO,,Sell,40637H109,36000.0,880.0,0.0 Healthcare Services Group Inc,HCSG,, ,421906108,4000.0,157.0,0.0 Hecla Mining Co,HL,, ,422704106,92000.0,16700.0,0.0 Jack Henry & Associates,JKHY,, ,426281101,12000.0,71.0,0.0 Heron Therapeutics Inc,HRTX,, ,427746102,3000.0,308.0,0.0 Hillenbrand,HI,, ,431571108,7000.0,170.0,0.0 Home Depot,HD,,Sell,437076102,18000.0,56.0,0.0 Homology Medicines,FIXX,, ,438083107,4000.0,481.0,0.0 Hubbell,HUBB,, ,443510607,16000.0,87.0,0.0 Hubspot Inc,HUBS,,Sell,443573100,89000.0,132.0,0.0 Humana,HUM,,Sell,444859102,22000.0,56.0,0.0 Incyte Corp,INCY,, ,45337C102,11000.0,165.0,0.0 Infinera,INFN,, ,45667G103,24000.0,2941.0,0.0 Insmed Inc,INSM,,Sell,457669307,19000.0,707.0,0.0 Inspire Medical Systems,INSP,,Sell,457730109,40000.0,170.0,0.0 Inogen Inc,INGN,, ,45780L104,6000.0,141.0,0.0 Intercept Pharmaceuticals Inc,ICPT,, ,45845P108,1000.0,101.0,0.0 Intersect ENT,XENT,,Buy,46071F103,12000.0,440.0,0.0 Invitae,NVTA,,New,46185L103,23000.0,800.0,0.0 Ironwood Pharmaceuticals Inc,IRWD,, ,46333X108,12000.0,935.0,0.0 Itron Inc,ITRI,, ,465741106,15000.0,204.0,0.0 J&J Snack Foods Corp,JJSF,, ,466032109,13000.0,83.0,0.0 Jaguar Health - US indemnity shares,JAGX,, ,47010C409,0.0,2033592.0,0.0 Johnson & Johnson,JNJ,, ,478160104,14000.0,89.0,0.0 Ziff Davis Inc,JCOM,, ,48123V102,10000.0,73.0,0.0 Keysight Technologies,KEYS,, ,49338L103,26000.0,158.0,0.0 Knowles Corp,KN,,New,49926D109,22000.0,1200.0,0.0 Kulicke & Soffa Industries Inc,KLIC,,New,501242101,29000.0,491.0,0.0 Lci Industries,LCII,, ,50189K103,12000.0,86.0,0.0 Harris Corp,LHX,, ,502431109,13000.0,61.0,0.0 Liberty Broadband Corp,LBRDK,, ,530307305,12000.0,70.0,0.0 Lightspeed POS,,,Sell,53227R106,30000.0,310.0,0.0 Lowes Cos,LOW,, ,548661107,14000.0,69.0,0.0 Lumentum Hdgs,LITE,,Sell,55024U109,12000.0,141.0,0.0 Marathon Digital Holdings,MARA,,Buy,565788106,11000.0,343.0,0.0 Medifast Inc,MED,,Sell,58470H101,21000.0,110.0,0.0 Mobile Telesystems ADR,MBT,sponsored adr, ,607409109,286000.0,29700.0,0.0 MongoDB Inc,MDB,,Sell,60937P106,100000.0,213.0,0.0 Monolithic Power Systems Inc,MPWR,,Sell,609839105,34000.0,70.0,0.0 NV5 Global,NVEE,, ,62945V109,14000.0,138.0,0.0 Nano Dimension ADR,NNDM,spons ads, ,63008G203,9000.0,1600.0,0.0 nCino,NCNO,,Buy,63947U107,16000.0,232.0,0.0 Nektar Therapeutics,NKTR,,Sell,640268108,25000.0,1376.0,0.0 Nevro Corp,NVRO,, ,64157F103,18000.0,154.0,0.0 New Relic,NEWR,,Sell,64829B100,53000.0,742.0,0.0 Nike,NKE,, ,654106103,15000.0,105.0,0.0 908 Devices,MASS,, ,65443P102,8000.0,249.0,0.0 nLIGHT,LASR,, ,65487K100,15000.0,542.0,0.0 Symantec Corp,NLOK,,Buy,668771108,14000.0,554.0,0.0 Novanta Inc,NOVT,,Buy,67000B104,32000.0,206.0,0.0 Nutanix Inc,NTNX,,Sell,67059N108,21000.0,563.0,0.0 On Semiconductor Corp,ON,,New,682189105,23000.0,500.0,0.0 1Life Healthcare,ONEM,, ,68269G107,9000.0,445.0,0.0 Opko Health Inc,OPK,,Sell,68375N103,24000.0,6635.0,0.0 Outset Medical,OM,, ,690145107,17000.0,346.0,0.0 Oxford Industries Inc,OXM,, ,691497309,7000.0,73.0,0.0 Ptc Therapeutics Inc,PTCT,, ,69366J200,9000.0,246.0,0.0 Pacific Biosciences of California,PACB,, ,69404D108,14000.0,561.0,0.0 PagerDuty,PD,,Sell,69553P100,23000.0,567.0,0.0 Pan American Silver Corp,PAAS,, ,697900108,105000.0,4500.0,0.0 Paychex,PAYX,, ,704326107,13000.0,116.0,0.0 Pfizer,PFE,,New,717081103,22000.0,500.0,0.0 Piedmont Lithium Inc,PLL,,New,72016P105,12000.0,212.0,0.0 Plantronics Inc,POLY,, ,727493108,7000.0,254.0,0.0 SCP Pool Corporation,POOL,,Sell,73278L105,33000.0,76.0,0.0 Precision BioSciences Inc,DTIL,,Buy,74019P108,17000.0,1468.0,0.0 Progyny,PGNY,, ,74340E103,22000.0,396.0,0.0 Proterra Inc,PTRA,,New,74374T109,107000.0,10600.0,0.0 Puma Biotechnology,PBYI,, ,74587V107,2000.0,252.0,0.0 Pure Storage Inc,PSTG,,Sell,74624M102,34000.0,1364.0,0.0 Quaker Chemical Corp,KWR,, ,747316107,20000.0,86.0,0.0 Qualcomm,QCOM,, ,747525103,26000.0,200.0,0.0 Quest Diagnostics,DGX,,Sell,74834L100,21000.0,145.0,0.0 Quidel Corp,QDEL,, ,74838J101,18000.0,128.0,0.0 Rambus Inc,RMBS,, ,750917106,16000.0,699.0,0.0 Regeneron Pharmaceuticals,REGN,,Sell,75886F107,33000.0,55.0,0.0 Ringcentral Inc,RNG,,Sell,76680R206,78000.0,358.0,0.0 Robert Half International Inc,RHI,, ,770323103,15000.0,151.0,0.0 Rollins Inc,ROL,,Sell,775711104,20000.0,562.0,0.0 Sei Investments Co,SEIC,,New,784117103,24000.0,400.0,0.0 Momentive Global Inc,SVMK,, ,78489X103,21000.0,1095.0,0.0 Sailpoint Technologies Holding,SAIL,, ,78781P105,17000.0,388.0,0.0 Sarepta Therapeutics Inc,SRPT,,Sell,803607100,16000.0,177.0,0.0 Schrodinger,SDGR,, ,80810D103,13000.0,242.0,0.0 Schweitzer-Maudit Int.,SWM,, ,808541106,9000.0,265.0,0.0 Seagen Inc,SGEN,, ,81181C104,22000.0,128.0,0.0 Seer,SEER,, ,81578P106,8000.0,223.0,0.0 Shake Shack Inc,SHAK,, ,819047101,14000.0,174.0,0.0 Silicon Laboratories Inc,SLAB,, ,826919102,18000.0,127.0,0.0 Silk Road Medical,SILK,, ,82710M100,13000.0,235.0,0.0 Smartsheet,SMAR,,Sell,83200N103,21000.0,311.0,0.0 Solaredge Technologies Inc,SEDG,,Buy,83417M104,426000.0,1609.0,0.0 Sorrento Therapeutics,SRNE,,Sell,83587F202,33000.0,4314.0,0.0 Stamps.Com,STMP,,Sell,852857200,16000.0,47.0,0.0 Stanley Black & Decker,SWK,, ,854502101,13000.0,77.0,0.0 Stitch Fix,SFIX,,Sell,860897107,33000.0,828.0,0.0 Stryker,SYK,, ,863667101,14000.0,54.0,0.0 Sumo Logic,SUMO,, ,86646P103,12000.0,726.0,0.0 Sunpower Corp,SPWR,,Sell,867652406,29000.0,1269.0,0.0 Synopsys,SNPS,,Sell,871607107,34000.0,112.0,0.0 Telus Corp,TU,, ,87971M103,9000.0,397.0,0.0 Tenable Holdings,TENB,, ,88025T102,15000.0,315.0,0.0 Texas Roadhouse Inc,TXRH,, ,882681109,12000.0,131.0,0.0 Thor Industries Inc,THO,, ,885160101,16000.0,133.0,0.0 Toro Co,TTC,,New,891092108,24000.0,245.0,0.0 Tractor Supply Co,TSCO,, ,892356106,31000.0,151.0,0.0 TransMedics Group,TMDX,,Buy,89377M109,40000.0,1222.0,0.0 TuSimple Hdgs,TSP,cl a, ,90089L108,13000.0,349.0,0.0 Ii-Vi Inc,IIVI,,Sell,902104108,32000.0,533.0,0.0 2U,TWOU,,Buy,90214J101,11000.0,319.0,0.0 Ultragenyx,RARE,, ,90400D108,10000.0,115.0,0.0 UnitedHealth,UNH,,New,91324P102,39000.0,100.0,0.0 Varonis Systems Inc,VRNS,,Buy,922280102,63000.0,1042.0,0.0 Veoneer Inc,VNE,,New,92336X109,24000.0,700.0,0.0 Verint Systems Inc,VRNT,, ,92343X100,18000.0,395.0,0.0 Veritone,VERI,, ,92347M100,14000.0,569.0,0.0 JDS Uniphase Corporation,VIAV,, ,925550105,18000.0,1142.0,0.0 ViewRay,VRAY,, ,92672L107,7000.0,911.0,0.0 Visteon Corp,VC,,New,92839U206,19000.0,200.0,0.0 Vuzix,VUZI,, ,92921W300,10000.0,924.0,0.0 WD-40 Co,WDFC,, ,929236107,13000.0,58.0,0.0 Vyne Therapeutics Inc,VYNE,, ,92941V209,138000.0,98762.0,0.0 Wal-Mart Stores,WMT,, ,931142103,14000.0,101.0,0.0 Wheaton Precious Metals,WPM,,Buy,962879102,767000.0,20416.0,0.0 John Wiley & Sons Inc,JWA,, ,968223206,8000.0,153.0,0.0 Williams-Sonoma Inc,WSM,, ,969904101,13000.0,76.0,0.0 XPEL,XPEL,,Sell,98379L100,22000.0,295.0,0.0 Xperi Holding Corp,XPER,,Sell,98390M103,34000.0,1793.0,0.0 Xencor Inc,XNCR,,Buy,98401F105,41000.0,1259.0,0.0 Yelp,YELP,, ,985817105,10000.0,262.0,0.0 Zynex,ZYXI,, ,98986M103,5000.0,437.0,0.0 Zynga Inc,ZNGA,,Sell,98986T108,22000.0,2863.0,0.0 Alkermes Plc,ALKS,, ,G01767105,6000.0,192.0,0.0 Amdocs,DOX,,Sell,G02602103,28000.0,365.0,0.0 Accenture 'A',ACN,, ,G1151C101,15000.0,48.0,0.0 GAN,GAN,, ,G3728V109,9000.0,572.0,0.0 International Game Technology,IGT,,New,G4863A108,29000.0,1100.0,0.0 Aptiv,APTV,,Sell,G6095L109,20000.0,134.0,0.0 Logitech International SA,LOGI,,Sell,H50430232,21000.0,235.0,0.0 Cognyte Software,CGNT,,Buy,M25133105,8000.0,369.0,0.0 Fiverr Intl,FVRR,, ,M4R82T106,11000.0,61.0,0.0 InMode,INMD,,Sell,M5425M103,49000.0,308.0,0.0 Clovis Oncology,CLVS,,Exit,189464100,0.0,-92.0,0.0 Mercury Computer Systems,MRCY,,Exit,589378108,0.0,-205.0,0.0 Hormel Foods Corp,HRL,,Exit,440452100,0.0,-264.0,0.0 Meredith Corp,MDP,,Exit,589433101,0.0,-293.0,0.0 Annaly Capital Man.,NLY,,Exit,035710409,0.0,-7446.0,0.0 Trimble Navigation,TRMB,,Exit,896239100,0.0,-359.0,0.0 Medalllia Inc,MDLA,,Exit,584021109,0.0,-542.0,0.0 ACM Research,ACMR,, ,00108J109,24000.0,220.0,0.0 Applied Optoelectronics,AAOI,,Exit,03823U102,0.0,-260.0,0.0 Cimpress,CMPR,,Exit,G2143T103,0.0,-84.0,0.0 Invesco Senior Income Trust,VVR,,Exit,46131H107,0.0,-3195695.0,-0.007 HEICO,HEI,,Exit,422806109,0.0,-179346.0,-0.012 iQIYI Inc ADR,IQ,spon adr,Exit,46267X108,0.0,-2552975.0,-0.019 Grifols ADR,GRFS,sp adr rep b nvt,Exit,398438408,0.0,-2948016.0,-0.025 HEICO 'A',HEIA,cl a,Exit,422806208,0.0,-1653301.0,-0.1 Wabtec,WAB,,Exit,929740108,0.0,-3660619.0,-0.147 EOG Resources,EOG,,Exit,26875P101,0.0,-3939421.0,-0.16