Orbimed Advisors Q2 2022 holdings

$5.52 Billion is the total value of Orbimed Advisors's 145 reported holdings in Q2 2022. The portfolio turnover from Q1 2022 to Q2 2022 was 20.8% .

 Value Shares↓ Weighting
SVA NewSINOVAC BIOTECH LTD$349,5002,718,735
+100.0%
6.33%
BMY SellBRISTOL-MYERS SQUIBB CO$193,940
+1.8%
2,518,700
-3.4%
3.51%
+13.8%
HUM SellHUMANA INC$171,173
+3.1%
365,700
-4.2%
3.10%
+15.2%
HZNP SellHORIZON THERAPEUTICS PUB L$168,178
-27.2%
2,108,555
-4.0%
3.05%
-18.7%
BSX SellBOSTON SCIENTIFIC CORP$162,851
-20.1%
4,369,500
-5.0%
2.95%
-10.7%
TPTX SellTURNING POINT THERAPEUTICS I$151,422
+179.3%
2,012,250
-0.3%
2.74%
+212.2%
SWTX  SPRINGWORKS THERAPEUTICS INC$148,417
-56.4%
6,028,3070.0%2.69%
-51.3%
UNH SellUNITEDHEALTH GROUP INC$144,433
-3.7%
281,200
-4.4%
2.62%
+7.6%
PFE SellPFIZER INC$143,868
-28.8%
2,744,000
-29.7%
2.61%
-20.5%
BMRN BuyBIOMARIN PHARMACEUTICAL INC$140,855
+10.9%
1,699,710
+3.2%
2.55%
+23.9%
ABBV SellABBVIE INC$122,497
-17.5%
799,800
-12.6%
2.22%
-7.8%
SGEN BuySEAGEN INC$121,646
+26.5%
687,500
+3.0%
2.20%
+41.3%
EWTX BuyEDGEWISE THERAPEUTICS INC$112,098
-17.1%
14,082,680
+1.0%
2.03%
-7.4%
VRTX SellVERTEX PHARMACEUTICALS INC$109,109
+4.5%
387,200
-3.2%
1.98%
+16.8%
ACET  ADICET BIO INC$108,728
-26.9%
7,447,1410.0%1.97%
-18.3%
SRRA  SIERRA ONCOLOGY INC$108,043
+71.6%
1,964,7700.0%1.96%
+91.8%
BHVN  BIOHAVEN PHARMACTL HLDG CO L$104,770
+22.9%
719,0340.0%1.90%
+37.3%
ISRG SellINTUITIVE SURGICAL INC$103,807
-35.6%
517,200
-3.2%
1.88%
-28.0%
ARQT SellARCUTIS BIOTHERAPEUTICS INC$101,897
-12.9%
4,781,646
-21.3%
1.85%
-2.7%
TCDA  TRICIDA INC$99,520
+17.8%
10,280,9470.0%1.80%
+31.6%
EW SellEDWARDS LIFESCIENCES CORP$96,165
-22.3%
1,011,300
-3.8%
1.74%
-13.2%
 THESEUS PHARMACEUTICALS INC$94,240
-52.0%
17,041,6680.0%1.71%
-46.4%
PMVP SellPMV PHARMACEUTICALS INC$93,524
-34.5%
6,563,077
-4.3%
1.70%
-26.8%
SYK SellSTRYKER CORPORATION$87,748
-28.2%
441,100
-3.5%
1.59%
-19.8%
NBIX SellNEUROCRINE BIOSCIENCES INC$82,814
+0.9%
849,545
-3.0%
1.50%
+12.8%
ARGX BuyARGENX SEsponsored adr$73,503
+37.3%
194,000
+14.3%
1.33%
+53.5%
MRTX SellMIRATI THERAPEUTICS INC$73,199
-45.4%
1,090,400
-33.1%
1.33%
-39.0%
GBT BuyGLOBAL BLOOD THERAPEUTICS IN$65,306
+19.6%
2,044,000
+29.6%
1.18%
+33.5%
TMO SellTHERMO FISHER SCIENTIFIC INC$61,608
-13.5%
113,400
-6.0%
1.12%
-3.4%
CRNX  CRINETICS PHARMACEUTICALS IN$59,622
-15.0%
3,196,8760.0%1.08%
-5.1%
NTRA BuyNATERA INC$58,878
-9.3%
1,661,353
+4.1%
1.07%
+1.4%
BuyPRELUDE THERAPEUTICS INCnonvoting$58,303
-24.4%
12,147,877
+2.1%
1.06%
-15.5%
CMPX BuyCOMPASS THERAPEUTICS INC$58,196
+96.3%
21,960,850
+1.5%
1.06%
+119.3%
EVH BuyEVOLENT HEALTH INCcl a$54,602
+20.7%
1,778,000
+27.0%
0.99%
+34.9%
PRLD  PRELUDE THERAPEUTICS INC$52,407
-24.3%
10,039,6910.0%0.95%
-15.4%
KNTE  KINNATE BIOPHARMA INC$50,990
+12.0%
4,043,6290.0%0.92%
+25.2%
RPTX  REPARE THERAPEUTICS INC$46,482
-1.8%
3,322,4880.0%0.84%
+9.8%
KROS  KEROS THERAPEUTICS INC$46,402
-49.2%
1,679,4170.0%0.84%
-43.2%
SNDX BuySYNDAX PHARMACEUTICALS INC$44,700
+19.2%
2,323,300
+7.6%
0.81%
+33.2%
ABCL  ABCELLERA BIOLOGICS INC$44,525
+9.2%
4,180,7680.0%0.81%
+22.1%
SIBN BuySI-BONE INC$44,458
-37.3%
3,368,000
+7.3%
0.81%
-29.9%
GRCL  GRACELL BIOTECHNOLOGIES INCsponsored ads$43,367
+136.0%
7,884,8700.0%0.79%
+163.8%
GH SellGUARDANT HEALTH INC$41,687
-52.5%
1,033,400
-22.0%
0.76%
-47.0%
MRSN BuyMERSANA THERAPEUTICS INC$41,633
+117.9%
9,011,437
+88.2%
0.75%
+143.2%
XENE BuyXENON PHARMACEUTICALS INC$40,434
+92.8%
1,329,200
+93.8%
0.73%
+115.6%
XTNT  XTANT MED HLDGS INC$37,894
-23.6%
72,943,9180.0%0.69%
-14.6%
SBTX  SILVERBACK THERAPEUTICS INC$37,061
+20.8%
8,740,8870.0%0.67%
+35.2%
VECT BuyVECTIVBIO HLDG AG$34,957
+39.2%
6,473,561
+21.4%
0.63%
+55.5%
ALPN  ALPINE IMMUNE SCIENCES INC$34,734
-5.1%
4,081,5920.0%0.63%
+5.9%
JANX  JANUX THERAPEUTICS INC$34,632
-14.9%
2,836,3860.0%0.63%
-4.8%
THC BuyTENET HEALTHCARE CORP$34,495
-36.1%
656,300
+4.5%
0.62%
-28.7%
KDNY BuyCHINOOK THERAPEUTICS INC$33,166
+42.9%
1,896,300
+33.7%
0.60%
+59.8%
PCVX  VAXCYTE INC$32,937
-9.9%
1,513,6590.0%0.60%
+0.7%
ACRS BuyACLARIS THERAPEUTICS INC$32,464
+19.2%
2,325,500
+47.2%
0.59%
+33.0%
IOVA SellIOVANCE BIOTHERAPEUTICS INC$30,895
-72.0%
2,798,441
-57.8%
0.56%
-68.7%
VRNA  VERONA PHARMA PLCsponsored ads$23,861
-16.0%
5,694,8410.0%0.43%
-6.3%
SCPH  SCPHARMACEUTICALS INC$23,122
-15.1%
4,797,1480.0%0.42%
-5.2%
BIIB SellBIOGEN INC$22,760
-8.3%
111,600
-5.3%
0.41%
+2.2%
TELA  TELA BIO INC$21,223
-39.7%
3,027,5420.0%0.38%
-32.6%
PASG BuyPASSAGE BIO INC$21,080
-7.3%
8,931,999
+21.8%
0.38%
+3.5%
DBTX  DECIBEL THERAPEUTICS INC$20,819
+38.5%
4,945,1920.0%0.38%
+54.5%
NPCE  NEUROPACE INC$19,861
-39.7%
4,012,2810.0%0.36%
-32.6%
 RXSIGHT INC$19,480
+13.7%
1,383,5000.0%0.35%
+27.0%
MGTX SellMEIRAGTX HLDGS PLC$18,937
-58.5%
2,501,618
-24.1%
0.34%
-53.6%
TVTX NewTRAVERE THERAPEUTICS INC$18,710772,200
+100.0%
0.34%
PGNY NewPROGYNY INC$18,156625,000
+100.0%
0.33%
GILD  GILEAD SCIENCES INC$17,777
+4.0%
287,6000.0%0.32%
+16.2%
ALXO BuyALX ONCOLOGY HLDGS INC$17,687
+68.3%
2,186,269
+251.7%
0.32%
+88.2%
IONS NewIONIS PHARMACEUTICALS INC$16,785453,400
+100.0%
0.30%
 ADAGIO THERAPEUTICS INC$16,584
-28.1%
5,056,0000.0%0.30%
-19.8%
QURE SellUNIQURE NV$16,307
-1.8%
874,849
-4.8%
0.30%
+9.7%
GHRS BuyGH RESEARCH PLCordinary shares$16,188
-38.1%
1,622,060
+13.5%
0.29%
-30.9%
RAPT BuyRAPT THERAPEUTICS INC$15,812
+99.0%
866,396
+139.8%
0.29%
+122.5%
 VENTYX BIOSCIENCES INC$15,768
-9.9%
1,289,2800.0%0.29%
+0.7%
AMGN  AMGEN INC$13,892
+0.6%
57,1000.0%0.25%
+12.5%
BLU  BELLUS HEALTH INC NEW$13,391
+33.0%
1,454,8000.0%0.24%
+49.1%
REGN NewREGENERON PHARMACEUTICALS$13,12322,200
+100.0%
0.24%
ISEE NewIVERIC BIO INC$13,0971,361,400
+100.0%
0.24%
IKNA  IKENA ONCOLOGY INC$12,997
-27.4%
2,933,9410.0%0.24%
-18.6%
NXTC  NEXTCURE INC$12,742
-3.3%
2,711,0130.0%0.23%
+7.9%
SGFY BuySIGNIFY HEALTH INC$12,420
+10.2%
900,000
+45.0%
0.22%
+23.0%
TBPH SellTHERAVANCE BIOPHARMA INC$12,414
-60.1%
1,370,250
-57.9%
0.22%
-55.4%
 BRIDGEBIO PHARMA INCnote 2.250% 2/0$12,150
-15.7%
30,000,0000.0%0.22%
-6.0%
VTGN BuyVISTAGEN THERAPEUTICS INC$11,811
-26.2%
13,421,283
+4.0%
0.21%
-17.7%
KZR NewKEZAR LIFE SCIENCES INC$11,7431,419,900
+100.0%
0.21%
ETNB  89BIO INC$11,782
-14.6%
3,658,8690.0%0.21%
-4.9%
MIST SellMILESTONE PHARMACEUTICALS IN$11,178
-32.6%
1,817,521
-29.7%
0.20%
-24.5%
DHRPRB  DANAHER CORPORATION5% conv pfd b$10,637
-16.2%
8,0390.0%0.19%
-6.3%
GMTX  GEMINI THERAPEUTICS INC$9,846
+21.6%
5,826,2240.0%0.18%
+35.9%
CMMB  CHEMOMAB THERAPEUTICS LTDsponsored ads$9,539
-22.9%
2,578,1740.0%0.17%
-13.9%
TERN  TERNS PHARMACEUTICALS INC$9,402
-16.5%
3,791,2040.0%0.17%
-7.1%
ORIC  ORIC PHARMACEUTICALS INC$9,352
-16.1%
2,087,5680.0%0.17%
-6.6%
 ERASCA INC$9,289
-35.2%
1,667,6930.0%0.17%
-27.9%
 BRIDGEBIO PHARMA INCnote 2.500% 3/1$9,000
-25.0%
20,000,0000.0%0.16%
-16.4%
JNCE BuyJOUNCE THERAPEUTICS INC$8,875
-54.3%
2,928,900
+2.4%
0.16%
-48.9%
SGEN NewSEAGEN INCcall$8,84750,000
+100.0%
0.16%
CGEM  CULLINAN ONCOLOGY INC$8,599
+22.4%
670,7870.0%0.16%
+36.8%
XBI  SPDR SER TRs&p biotech$8,303
-17.4%
111,8000.0%0.15%
-8.0%
FUSN  FUSION PHARMACEUTICALS INC$8,030
-68.0%
3,224,7700.0%0.15%
-64.0%
MREO  MEREO BIOPHARMA GROUP PLCads$7,9630.0%7,109,9540.0%0.14%
+11.6%
AVTE SellAEROVATE THERAPEUTICS INC$7,480
-20.0%
478,579
-6.2%
0.14%
-10.5%
GLTO  GALECTO INC$7,077
-21.4%
4,090,9370.0%0.13%
-12.3%
SYBX  SYNLOGIC INC$6,934
-52.1%
6,029,9950.0%0.13%
-46.4%
CRVS  CORVUS PHARMACEUTICALS INC$6,875
-39.6%
6,943,6540.0%0.12%
-32.4%
LUNG  PULMONX CORP$6,403
-40.7%
435,0000.0%0.12%
-33.7%
SRRK NewSCHOLAR ROCK HLDG CORP$5,9101,076,540
+100.0%
0.11%
CLXPF  CYBIN INC$5,886
-31.5%
10,524,3000.0%0.11%
-23.0%
HARP  HARPOON THERAPEUTICS INC$5,805
-61.6%
3,039,5080.0%0.10%
-57.1%
MIRM BuyMIRUM PHARMACEUTICALS INC$5,439
+814.1%
279,500
+935.2%
0.10%
+890.0%
IMRA  IMARA INC$5,352
-35.1%
4,386,5680.0%0.10%
-27.6%
NTRA  NATERA INCcall$5,316
-12.9%
150,0000.0%0.10%
-3.0%
IMCR BuyIMMUNOCORE HLDGS PLCads$4,891
+27.7%
131,100
+2.3%
0.09%
+43.5%
 NANOSTRING TECHNOLOGIES INCnote 2.625% 3/0$4,851
-20.3%
6,000,0000.0%0.09%
-11.1%
GRAY  GRAYBUG VISION INC$4,538
-11.4%
4,163,3470.0%0.08%
-1.2%
VOR  VOR BIOPHARMA INC$4,142
-17.7%
833,3330.0%0.08%
-8.5%
APLT NewAPPLIED THERAPEUTICS INC$4,0304,250,000
+100.0%
0.07%
BNR SellBURNING ROCK BIOTECH LTDsponsored ads$4,044
-70.0%
1,389,802
-4.3%
0.07%
-66.7%
ACHL  ACHILLES THERAPEUTICS PLCsponsored ads$3,994
-14.3%
1,584,8450.0%0.07%
-5.3%
CTMX  CYTOMX THERAPEUTICS INC$3,889
-31.5%
2,124,9750.0%0.07%
-23.9%
NVAX NewNOVAVAX INCcall$3,85775,000
+100.0%
0.07%
CLDX SellCELLDEX THERAPEUTICS INC NEW$3,038
-78.0%
112,700
-72.2%
0.06%
-75.4%
AFIB  ACUTUS MED INC$2,966
-19.4%
2,648,3860.0%0.05%
-10.0%
LOGC  LOGICBIO THERAPEUTICS INC$2,967
-48.5%
8,466,7830.0%0.05%
-41.9%
MREO SellMEREO BIOPHARMA GROUP PLCads$2,914
-74.4%
2,601,468
-74.4%
0.05%
-71.2%
MGTA  MAGENTA THERAPEUTICS INC$2,701
-58.6%
2,250,9530.0%0.05%
-53.8%
ABCL NewABCELLERA BIOLOGICS INCcall$2,663250,000
+100.0%
0.05%
OCX SellONCOCYTE CORP$2,553
-51.0%
2,837,800
-18.8%
0.05%
-45.2%
TARA  PROTARA THERAPEUTICS INC$2,434
-42.7%
830,6410.0%0.04%
-36.2%
GRPH SellGRAPHITE BIO INC$2,333
-70.8%
848,412
-45.8%
0.04%
-67.4%
NMTR Sell9 METERS BIOPHARMA INC$2,218
-64.0%
8,505,729
-17.2%
0.04%
-60.0%
PHGE  BIOMX INC$2,054
-62.2%
2,813,4890.0%0.04%
-58.0%
GH NewGUARDANT HEALTH INCcall$2,01750,000
+100.0%
0.04%
OMIC SellSINGULAR GENOMICS SYSTEMS IN$2,065
-85.8%
540,697
-76.5%
0.04%
-84.3%
KALV NewKALVISTA PHARMACEUTICALS INC$1,824185,400
+100.0%
0.03%
 SIGHT SCIENCES INC$1,798
-22.2%
200,0000.0%0.03%
-10.8%
EYPT NewEYEPOINT PHARMACEUTICALS INC$1,685214,100
+100.0%
0.03%
SRPT SellSAREPTA THERAPEUTICS INC$1,499
-50.9%
20,000
-48.8%
0.03%
-46.0%
XFOR  X4 PHARMACEUTICALS INC$1,326
-44.8%
1,373,8490.0%0.02%
-38.5%
SellSONENDO INC$1,244
-84.2%
723,478
-63.2%
0.02%
-82.0%
TALS SellTALARIS THERAPEUTICS INC$1,064
-56.3%
235,995
-4.5%
0.02%
-51.3%
 VIGIL NEUROSCIENCE INC$1,061
-63.3%
411,1910.0%0.02%
-59.6%
AGLE SellAEGLEA BIOTHERAPEUTICS INC$908
-86.6%
1,797,221
-39.2%
0.02%
-85.5%
LBPH  LONGBOARD PHARMACEUTICALS IN$351
-42.1%
113,5000.0%0.01%
-40.0%
APTX  APTINYX INC$300
-75.5%
538,5000.0%0.01%
-75.0%
ExitOWLET INC*w exp 09/14/202$0-220,704
-100.0%
-0.00%
LABP ExitLANDOS BIOPHARMA INC$0-283,217
-100.0%
-0.01%
ExitPYXIS ONCOLOGY INC$0-143,640
-100.0%
-0.01%
ExitFIELD TRIP HEALTH LTD$0-576,930
-100.0%
-0.01%
CABA ExitCABALETTA BIO INC$0-577,509
-100.0%
-0.02%
GBT ExitGLOBAL BLOOD THERAPEUTICS INcall$0-50,000
-100.0%
-0.03%
ASLN ExitASLAN PHARMACEUTICALS LTDads$0-1,941,219
-100.0%
-0.03%
IMAB ExitI MABsponsored ads$0-111,120
-100.0%
-0.03%
ExitEXSCIENTIA PLCads$0-125,000
-100.0%
-0.03%
ALBO ExitALBIREO PHARMA INC$0-194,000
-100.0%
-0.09%
GLPG ExitGALAPAGOS NVspon adr$0-208,225
-100.0%
-0.21%
ILMN ExitILLUMINA INC$0-45,100
-100.0%
-0.26%
RARE ExitULTRAGENYX PHARMACEUTICAL IN$0-227,600
-100.0%
-0.27%
NSTG ExitNANOSTRING TECHNOLOGIES INC$0-1,157,387
-100.0%
-0.65%
DXCM ExitDEXCOM INC$0-149,900
-100.0%
-1.24%

Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):

The following EDGAR filing(s) were analyzed to create this report:

The EDGAR filing(s) were signed by:

  • Sven H. Borho — Member

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EDGAR filings