$9.89 Billion is the total value of Orbimed Advisors's 160 reported holdings in Q2 2021. The portfolio turnover from Q1 2021 to Q2 2021 was 0.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BMY | BRISTOL-MYERS SQUIBB CO | $301,719,000 | +5.8% | 4,515,400 | 0.0% | 3.05% | +14.5% | |
| EWTX | EDGEWISE THERAPEUTICS INC | $297,440,000 | -34.4% | 13,944,680 | 0.0% | 3.01% | -29.0% | |
| BSX | BOSTON SCIENTIFIC CORP | $295,925,000 | +10.6% | 6,920,600 | 0.0% | 2.99% | +19.7% | |
| MRK | MERCK & CO INC | $290,269,000 | +0.9% | 3,732,400 | 0.0% | 2.94% | +9.1% | |
| PRLD | PRELUDE THERAPEUTICS INC | $287,436,000 | -33.9% | 10,039,691 | 0.0% | 2.91% | -28.5% | |
| SBTX | SILVERBACK THERAPEUTICS INC | $270,006,000 | -29.2% | 8,740,887 | 0.0% | 2.73% | -23.4% | |
| PMVP | PMV PHARMACEUTICALS INC | $250,407,000 | +3.9% | 7,330,423 | 0.0% | 2.53% | +12.4% | |
| PRELUDE THERAPEUTICS INCnonvoting | $249,889,000 | -40.7% | 11,895,652 | 0.0% | 2.53% | -35.9% | ||
| TPTX | TURNING POINT THERAPEUTICS I | $184,231,000 | -17.5% | 2,361,327 | 0.0% | 1.86% | -10.8% | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | $172,906,000 | -17.8% | 6,645,100 | 0.0% | 1.75% | -11.1% | |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | $165,755,000 | -5.7% | 6,073,850 | 0.0% | 1.68% | +2.1% | |
| ISRG | INTUITIVE SURGICAL INC | $128,382,000 | +24.5% | 139,600 | 0.0% | 1.30% | +34.6% | |
| DXCM | DEXCOM INC | $126,990,000 | +18.8% | 297,400 | 0.0% | 1.28% | +28.5% | |
| XTNT | XTANT MED HLDGS INC | $118,784,000 | -30.9% | 72,873,494 | 0.0% | 1.20% | -25.3% | |
| EW | EDWARDS LIFESCIENCES CORP | $116,661,000 | +23.8% | 1,126,400 | 0.0% | 1.18% | +33.9% | |
| RPTX | REPARE THERAPEUTICS INC | $106,833,000 | +1.6% | 3,426,325 | 0.0% | 1.08% | +10.0% | |
| GRCL | GRACELL BIOTECHNOLOGIES INCsponsored ads | $102,503,000 | -15.6% | 7,884,870 | 0.0% | 1.04% | -8.6% | |
| AFIB | ACUTUS MED INC | $93,016,000 | +27.0% | 5,477,958 | 0.0% | 0.94% | +37.4% | |
| PASG | PASSAGE BIO INC | $92,189,000 | -24.3% | 6,962,899 | 0.0% | 0.93% | -18.1% | |
| KNTE | KINNATE BIOPHARMA INC | $89,580,000 | -25.3% | 3,847,929 | 0.0% | 0.91% | -19.2% | |
| SYK | STRYKER CORPORATION | $87,633,000 | +6.6% | 337,400 | 0.0% | 0.89% | +15.4% | |
| AUPH | AURINIA PHARMACEUTICALS INC | $78,655,000 | -0.2% | 6,069,032 | 0.0% | 0.80% | +8.0% | |
| SVA | SINOVAC BIOTECH LTD | $76,800,000 | +6.7% | 2,839,500 | 0.0% | 0.78% | +15.5% | |
| ACET | ADICET BIO INC | $74,426,000 | -21.3% | 7,232,856 | 0.0% | 0.75% | -14.9% | |
| KROS | KEROS THERAPEUTICS INC | $71,325,000 | -31.0% | 1,679,417 | 0.0% | 0.72% | -25.4% | |
| ETNB | 89BIO INC | $69,741,000 | -21.0% | 3,729,442 | 0.0% | 0.70% | -14.6% | |
| MGTX | MEIRAGTX HLDGS PLC | $63,595,000 | +7.4% | 4,102,925 | 0.0% | 0.64% | +16.1% | |
| TMO | THERMO FISHER SCIENTIFIC INC | $55,643,000 | +10.5% | 110,300 | 0.0% | 0.56% | +19.5% | |
| CMMB | CHEMOMAB THERAPEUTICS LTDsponsored ads | $49,037,000 | -33.8% | 2,578,174 | 0.0% | 0.50% | -28.3% | |
| TELA | TELA BIO INC | $48,774,000 | +8.1% | 3,027,542 | 0.0% | 0.49% | +16.8% | |
| APLT | APPLIED THERAPEUTICS INC | $46,909,000 | +10.8% | 2,257,387 | 0.0% | 0.47% | +19.7% | |
| TERN | TERNS PHARMACEUTICALS INC | $46,480,000 | -44.3% | 3,791,204 | 0.0% | 0.47% | -39.7% | |
| DBTX | DECIBEL THERAPEUTICS INC | $42,529,000 | -24.3% | 4,945,192 | 0.0% | 0.43% | -18.1% | |
| TCDA | TRICIDA INC | $41,534,000 | -18.3% | 9,614,280 | 0.0% | 0.42% | -11.8% | |
| ORIC | ORIC PHARMACEUTICALS INC | $41,352,000 | -27.8% | 2,337,574 | 0.0% | 0.42% | -21.9% | |
| IKNA | IKENA ONCOLOGY INC | $41,193,000 | -50.3% | 2,933,941 | 0.0% | 0.42% | -46.2% | |
| SIBN | SI-BONE INC | $41,078,000 | -1.1% | 1,305,300 | 0.0% | 0.42% | +7.0% | |
| GMTX | GEMINI THERAPEUTICS INC | $37,696,000 | -52.3% | 5,826,224 | 0.0% | 0.38% | -48.4% | |
| LOGC | LOGICBIO THERAPEUTICS INC | $37,593,000 | -39.0% | 8,466,783 | 0.0% | 0.38% | -34.0% | |
| VRNA | VERONA PHARMA PLCsponsored ads | $37,244,000 | -21.8% | 5,694,841 | 0.0% | 0.38% | -15.3% | |
| CGEM | CULLINAN ONCOLOGY INC | $29,513,000 | -38.2% | 1,146,145 | 0.0% | 0.30% | -33.1% | |
| SCPH | SCPHARMACEUTICALS INC | $29,311,000 | -8.1% | 4,797,148 | 0.0% | 0.30% | -0.7% | |
| KALA | KALA PHARMACEUTICALS INC | $28,965,000 | -21.4% | 5,465,030 | 0.0% | 0.29% | -14.8% | |
| SRRA | SIERRA ONCOLOGY INC | $28,763,000 | +13.0% | 1,477,320 | 0.0% | 0.29% | +22.3% | |
| AGLE | AEGLEA BIOTHERAPEUTICS INC | $27,948,000 | -12.1% | 4,015,524 | 0.0% | 0.28% | -4.7% | |
| ALPN | ALPINE IMMUNE SCIENCES INC | $27,639,000 | -15.1% | 3,070,955 | 0.0% | 0.28% | -7.9% | |
| APTOSE BIOSCIENCES INC | $26,660,000 | -44.4% | 8,030,000 | 0.0% | 0.27% | -39.9% | ||
| FUSN | FUSION PHARMACEUTICALS INC | $26,056,000 | -24.6% | 3,224,770 | 0.0% | 0.26% | -18.3% | |
| GRAY | GRAYBUG VISION INC | $22,607,000 | -2.2% | 4,163,347 | 0.0% | 0.23% | +6.0% | |
| NXTC | NEXTCURE INC | $21,769,000 | -19.8% | 2,711,013 | 0.0% | 0.22% | -13.4% | |
| CRVS | CORVUS PHARMACEUTICALS INC | $21,502,000 | -13.3% | 8,053,298 | 0.0% | 0.22% | -6.5% | |
| IMRA | IMARA INC | $21,487,000 | -6.4% | 2,719,902 | 0.0% | 0.22% | +0.9% | |
| GLTO | GALECTO INC | $20,700,000 | -16.7% | 4,090,937 | 0.0% | 0.21% | -9.9% | |
| GILD | GILEAD SCIENCES INC | $19,804,000 | +6.5% | 287,600 | 0.0% | 0.20% | +14.9% | |
| CTIC | CTI BIOPHARMA CORP | $18,802,000 | -14.1% | 7,520,600 | 0.0% | 0.19% | -7.3% | |
| VRCA | VERRICA PHARMACEUTICALS INC | $16,721,000 | -25.4% | 1,479,733 | 0.0% | 0.17% | -19.5% | |
| GLPG | GALAPAGOS NVspon adr | $15,907,000 | -10.6% | 230,905 | 0.0% | 0.16% | -3.0% | |
| ACHL | ACHILLES THERAPEUTICS PLCsponsored ads | $15,516,000 | -40.8% | 1,584,845 | 0.0% | 0.16% | -35.9% | |
| VOR | VOR BIOPHARMA INC | $15,542,000 | -56.7% | 833,333 | 0.0% | 0.16% | -53.3% | |
| MIST | MILESTONE PHARMACEUTICALS IN | $14,211,000 | -5.0% | 2,583,821 | 0.0% | 0.14% | +2.9% | |
| RLAY | RELAY THERAPEUTICS INC | $12,807,000 | +5.8% | 350,000 | 0.0% | 0.13% | +15.0% | |
| ALEC | ALECTOR INC | $12,737,000 | +3.4% | 611,478 | 0.0% | 0.13% | +12.2% | |
| PHGE | BIOMX INC | $12,632,000 | -23.3% | 2,313,489 | 0.0% | 0.13% | -16.9% | |
| BLU | BELLUS HEALTH INC NEW | $12,272,000 | -18.7% | 3,954,800 | 0.0% | 0.12% | -12.1% | |
| OCX | ONCOCYTE CORP | $12,054,000 | +10.6% | 2,100,000 | 0.0% | 0.12% | +19.6% | |
| SYRS | SYROS PHARMACEUTICALS INC | $10,014,000 | -27.1% | 1,837,500 | 0.0% | 0.10% | -21.7% | |
| CBIO | CATALYST BIOSCIENCES INC | $9,174,000 | -14.1% | 2,118,600 | 0.0% | 0.09% | -7.0% | |
| XFOR | X4 PHARMACEUTICALS INC | $8,930,000 | -24.5% | 1,373,849 | 0.0% | 0.09% | -18.9% | |
| ARPO | AERPIO PHARMACEUTICALS INC | $8,778,000 | +31.0% | 5,193,946 | 0.0% | 0.09% | +41.3% | |
| ASLN | ASLAN PHARMACEUTICALS LTDads | $8,316,000 | -1.5% | 2,520,000 | 0.0% | 0.08% | +6.3% | |
| ALXO | ALX ONCOLOGY HLDGS INC | $8,202,000 | -25.8% | 150,000 | 0.0% | 0.08% | -19.4% | |
| NRIX | NURIX THERAPEUTICS INC | $7,959,000 | -14.7% | 300,000 | 0.0% | 0.08% | -6.9% | |
| LABP | LANDOS BIOPHARMA INC | $7,866,000 | +19.9% | 681,000 | 0.0% | 0.08% | +31.1% | |
| DYN | DYNE THERAPEUTICS INC | $7,364,000 | +35.5% | 350,000 | 0.0% | 0.07% | +45.1% | |
| OTIC | OTONOMY INC | $7,248,000 | -12.5% | 3,250,000 | 0.0% | 0.07% | -5.2% | |
| NBTX | NANOBIOTIX SAsponsored ads | $6,890,000 | -8.4% | 500,000 | 0.0% | 0.07% | 0.0% | |
| RXDX | PROMETHEUS BIOSCIENCES INC | $6,140,000 | +34.5% | 250,000 | 0.0% | 0.06% | +44.2% | |
| LUNG | PULMONX CORP | $5,515,000 | -3.6% | 125,000 | 0.0% | 0.06% | +5.7% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $5,100,000 | -8.8% | 500,000 | 0.0% | 0.05% | 0.0% | |
| SBBP | STRONGBRIDGE BIOPHARMA PLC | $5,182,000 | +7.6% | 1,744,669 | 0.0% | 0.05% | +15.6% | |
| TARA | PROTARA THERAPEUTICS INC | $4,383,000 | -38.1% | 450,000 | 0.0% | 0.04% | -33.3% | |
| ADAG | ADAGENE INCads | $3,729,000 | -24.5% | 275,000 | 0.0% | 0.04% | -17.4% | |
| IFRX | INFLARX NV | $3,160,000 | -23.9% | 1,064,118 | 0.0% | 0.03% | -17.9% |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-08-16
About Orbimed Advisors
Orbimed Advisors is a leading healthcare-focused investment firm that manages over $16 billion in assets. The firm was founded in 1998 by Samuel Isaly, who has over 50 years of experience in the healthcare industry. Isaly is widely regarded as a pioneer in the field of healthcare investing and has been recognized for his contributions to the industry by numerous organizations.
Orbimed Advisors has a team of over 100 professionals, including investment professionals, research analysts, and operational experts. The firm has offices in New York, San Francisco, Shanghai, and Mumbai, and invests in companies across the healthcare spectrum, including biotechnology, pharmaceuticals, medical devices, and healthcare services.
The firm's investment philosophy is based on a deep understanding of the healthcare industry and a rigorous approach to due diligence. Orbimed Advisors seeks to identify companies with innovative technologies and strong management teams that have the potential to transform the healthcare landscape.
Orbimed Advisors has a strong track record of success, with numerous successful investments in companies such as Juno Therapeutics, Spark Therapeutics, and Kite Pharma. The firm's leadership team, which includes CEO Sven Borho, COO Jonathan Silverstein, and Chief Investment Officer Carl Gordon, has decades of experience in the healthcare industry and is widely respected for their expertise and insights.
Overall, Orbimed Advisors is a leading healthcare investment firm that has a proven track record of success and a deep understanding of the healthcare industry. Investors looking to gain exposure to the healthcare sector may want to consider Orbimed Advisors as a potential investment opportunity.
It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| BIOGEN INC | 42 | Q3 2023 | 5.0% |
| VERTEX PHARMACEUTICALS INC | 42 | Q3 2023 | 3.7% |
| THERMO FISHER SCIENTIFIC INC | 42 | Q3 2023 | 3.2% |
| SINOVAC BIOTECH LTD | 41 | Q3 2023 | 7.2% |
| NEUROCRINE BIOSCIENCES INC | 41 | Q3 2023 | 2.7% |
| BOSTON SCIENTIFIC CORP | 40 | Q3 2023 | 5.6% |
| BRISTOL-MYERS SQUIBB CO | 40 | Q2 2023 | 5.2% |
| AMGEN INC | 40 | Q3 2023 | 5.5% |
| INTUITIVE SURGICAL INC | 40 | Q3 2023 | 3.8% |
| GILEAD SCIENCES INC | 39 | Q3 2023 | 5.5% |
View Orbimed Advisors's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Ikena Oncology, Inc. | September 21, 2023 | 2,189,111 | 5.2% |
| Galecto, Inc. | September 18, 2023 | 749,557 | 2.8% |
| PMV Pharmaceuticals, Inc. | August 23, 2023 | 6,563,077 | 13.5% |
| Gracell Biotechnologies Inc. | August 11, 2023 | 7,641,531 | 8.0% |
| Xtant Medical Holdings, Inc. | August 03, 2023 | 73,114,592 | 56.7% |
| Turnstone Biologics Corp. | July 24, 2023 | 3,099,265 | 13.4% |
| Prelude Therapeutics Inc | May 24, 2023 | 15,716,642 | 28.6% |
| VectivBio Holding AG | May 24, 2023 | 5,156,561 | 7.7% |
| Fusion Pharmaceuticals Inc. | May 16, 2023 | 2,930,670 | 4.6% |
| Verona Pharma plc | May 16, 2023 | 3,777,778 | 4.8% |
View Orbimed Advisors's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 4 | 2024-04-23 |
| 4 | 2024-04-18 |
| 4 | 2024-04-15 |
| 3/A | 2024-04-12 |
| SC 13D/A | 2024-04-12 |
| 4 | 2024-04-05 |
| SC 13D/A | 2024-04-04 |
| 3 | 2024-04-03 |
| SC 13D | 2024-03-28 |
| 3 | 2024-03-27 |
View Orbimed Advisors's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.