RA Capital Management Q4 2020 13F Holdings

RA Capital Management Q4 2020 holdings
TickerName ValueShares↓ Weighting
ASND ASCENDIS PHARMA A Ssponsored adrReduce  $978,221
7.3%
5,865,338
-0.8%
13.67%
-18.0%
TGTX TG THERAPEUTICS INCReduce  $451,818
91.3%
8,685,471
-1.6%
6.32%
46.2%
NVAX NOVAVAX INCAdd  $422,463
225.3%
3,788,564
216.1%
5.91%
148.6%
NKTX NKARTA INC  $344,547
104.5%
5,605,1290.0%4.82%
56.3%
FMTX FORMA THERAPEUTICS HLD...  $314,507
-30.0%
9,011,6510.0%4.40%
-46.5%
ARVN ARVINAS INC  $311,937
259.7%
3,672,8720.0%4.36%
174.9%
CCXI CHEMOCENTRYX INCReduce  $295,764
11.8%
4,776,548
-1.0%
4.13%
-14.5%
AVIR ATEA PHARMACEUTICALS INCNew  $224,2945,368,4513.14%
ITOS ITEOS THERAPEUTICS INC  $149,392
37.1%
4,417,2580.0%2.09%
4.8%
KINNATE BIOPHARMA INCNew  $142,9323,593,0522.00%
AXSM AXSOME THERAPEUTICS INCReduce  $134,869
-7.0%
1,655,447
-18.7%
1.89%
-28.9%
KROS KEROS THERAPEUTICS INC  $132,263
82.9%
1,875,0000.0%1.85%
39.8%
PHAT PHATHOM PHARMACEUTICAL...  $127,067
-9.4%
3,825,0080.0%1.78%
-30.8%
RYTM RHYTHM PHARMACEUTICALS...Reduce  $124,244
11.5%
4,179,067
-18.7%
1.74%
-14.8%
TVTX TRAVERE THERAPEUTICS INCNew  $124,2254,557,8671.74%
IMGN IMMUNOGEN INCAdd  $118,793
368.7%
18,417,458
161.6%
1.66%
258.2%
RCKT ROCKET PHARMACEUTICALS...New  $117,1432,136,0811.64%
ETNB 89BIO INC  $115,422
-5.0%
4,736,2140.0%1.61%
-27.4%
ZGNX ZOGENIX INCReduce  $106,859
8.6%
5,345,631
-2.6%
1.49%
-17.0%
PMVP PMV PHARMACEUTICALS INC  $105,198
73.3%
1,710,2650.0%1.47%
32.4%
OLMA OLEMA PHARMACEUTICALS INCNew  $103,3912,150,4041.45%
ADVM ADVERUM BIOTECHNOLOGIE...Add  $103,006
6.3%
9,502,383
1.0%
1.44%
-18.8%
MGNX MACROGENICS INC  $100,017
-9.3%
4,375,2170.0%1.40%
-30.6%
PCVX VAXCYTE INCReduce  $98,593
-62.2%
3,710,699
-29.8%
1.38%
-71.1%
IGMS IGM BIOSCIENCES INC  $86,765
19.6%
982,7230.0%1.21%
-8.6%
BDTX BLACK DIAMOND THERAPEU...  $83,006
6.0%
2,589,9040.0%1.16%
-19.0%
SILVERBACK THERAPEUTIC...New  $80,7331,742,1861.13%
TRILLIUM THERAPEUTICS INCReduce  $77,823
-11.1%
5,290,481
-14.2%
1.09%
-32.1%
SLDB SOLID BIOSCIENCES INCAdd  $75,622
715.0%
9,976,569
118.3%
1.06%
522.9%
KALA KALA PHARMACEUTICALS INC  $73,730
-9.6%
10,874,6130.0%1.03%
-30.9%
FPRX FIVE PRIME THERAPEUTIC...New  $72,8914,285,1611.02%
INBX INHIBRX INC  $70,193
83.2%
2,129,0030.0%0.98%
40.0%
LEGN LEGEND BIOTECH CORPsponsored ads  $67,818
-8.8%
2,408,2920.0%0.95%
-30.3%
CRIS CURIS INCNew  $63,1277,707,7900.88%
WVE WAVE LIFE SCIENCES LTD  $61,191
-7.3%
7,775,2070.0%0.86%
-29.2%
CRDF CARDIFF ONCOLOGY INC  $59,187
26.8%
3,290,0000.0%0.83%
-3.1%
DYN DYNE THERAPEUTICS INC  $58,906
4.0%
2,805,0450.0%0.82%
-20.5%
CNST CONSTELLATION PHARMCET...New  $53,3591,852,7460.75%
PACB PACIFIC BIOSCIENCES OF...New  $51,5691,987,9970.72%
GERN GERON CORP  $47,901
-8.6%
30,126,2990.0%0.67%
-30.2%
STRO SUTRO BIOPHARMA INC  $45,986
116.0%
2,118,2120.0%0.64%
65.1%
CCCC C4 THERAPEUTICS INCNew  $45,6391,377,5690.64%
AKUS AKOUOS INC  $45,237
-13.3%
2,281,2490.0%0.63%
-33.7%
RLAY RELAY THERAPEUTICS INC  $41,560
-2.4%
1,000,0000.0%0.58%
-25.4%
INZY INOZYME PHARMA INC  $41,355
-21.5%
2,003,6530.0%0.58%
-40.0%
ORTX ORCHARD THERAPEUTICS PLCads  $41,155
-18.7%
12,315,2130.0%0.58%
-37.9%
ARDX ARDELYX INCReduce  $39,875
21.3%
6,163,086
-1.6%
0.56%
-7.3%
CERE CEREVEL THERAPEUTICS H...New  $36,4762,200,0000.51%
ARQT ARCUTIS BIOTHERAPEUTIC...  $32,777
-4.0%
1,165,1840.0%0.46%
-26.6%
LRMR LARIMAR THERAPEUTICS INC  $32,439
41.1%
1,515,1510.0%0.45%
7.9%
VRNA VERONA PHARMA PLCsponsored ads  $31,8240.0%5,100,0000.0%0.44%
-23.6%
PAND PANDION THERAPEUTICS INC  $26,285
29.6%
1,770,0230.0%0.37%
-1.0%
ALEC ALECTOR INCReduce  $24,463
-35.8%
1,616,879
-55.3%
0.34%
-51.0%
CNCE CONCERT PHARMACEUTICAL...Reduce  $23,049
26.3%
1,823,520
-1.9%
0.32%
-3.5%
SNDX SYNDAX PHARMACEUTICALS...  $22,753
50.7%
1,023,0670.0%0.32%
15.2%
STSA SATSUMA PHARMACEUTICAL...  $21,583
18.5%
4,681,8580.0%0.30%
-9.4%
ORIC ORIC PHARMACEUTICALS INCNew  $19,768584,0000.28%
SCPH SCPHARMACEUTICALS INC  $18,615
-29.0%
3,518,9980.0%0.26%
-45.7%
MARINUS PHARMACEUTICAL...New  $15,8601,300,0000.22%
VXRT VAXART INCReduce  $15,658
-78.2%
2,742,271
-74.6%
0.22%
-83.4%
MIST MILESTONE PHARMACEUTIC...Reduce  $15,596
-11.9%
2,327,714
-3.8%
0.22%
-32.7%
OCUL OCULAR THERAPEUTIX INCReduce  $15,525
-25.2%
750,000
-72.5%
0.22%
-42.8%
BCTG BCTG ACQUISITION CORP  $14,300
10.4%
1,250,0000.0%0.20%
-15.6%
RPTX REPARE THERAPEUTICS INC  $14,029
11.5%
409,0000.0%0.20%
-14.8%
BLSA BCLS ACQUISITION CORPNew  $13,9251,250,0000.19%
ADAP ADAPTIMMUNE THERAPEUTI...sponds adrReduce  $13,470
-85.1%
2,499,025
-77.9%
0.19%
-88.6%
COGT COGENT BIOSCIENCES INCNew  $11,5181,025,6410.16%
ARYA ARYA SCIENCES ACQUISIT...  $10,850
0.3%
1,000,0000.0%0.15%
-23.3%
FRAZIER LIFESCIENCES A...unit 12/09/2025New  $10,3801,000,0000.15%
TXMD THERAPEUTICSMD INCNew  $9,4537,812,5000.13%
LYRA LYRA THERAPEUTICS INC  $9,301
0.5%
815,8490.0%0.13%
-23.2%
PASG PASSAGE BIO INC  $8,250
95.0%
322,6300.0%0.12%
49.1%
HSAQ HEALTH SCIENCES ACQ CO...  $8,006
16.5%
625,0000.0%0.11%
-11.0%
CRNX CRINETICS PHARMACEUTIC...Reduce  $7,959
-78.2%
564,102
-75.8%
0.11%
-83.3%
HLXA HELIX ACQUISITION CORPNew  $7,959700,0000.11%
FVAM 5 01 ACQUISITION CORPNew  $7,628750,0000.11%
MGEN MIRAGEN THERAPEUTICS INCNew  $7,434451,9320.10%
IMRA IMARA INCReduce  $5,486
8.0%
248,804
-0.4%
0.08%
-17.5%
PROF PROFOUND MEDICAL CORPNew  $3,954192,3110.06%
XFOR X4 PHARMACEUTICALS INCReduce  $3,453
-8.8%
536,962
-4.0%
0.05%
-30.3%
CEREW CEREVEL THERAPEUTICS H...*w exp 06/09/2027New  $1,318233,3330.02%
OVID OVID THERAPEUTICS INC  $658
-59.8%
285,0000.0%0.01%
-69.3%
EPIX ESSA PHARMA INCSold out  $0-470,428-0.06%
CLDX CELLDEX THERAPEUTICS I...Sold out  $0-353,072-0.10%
GRTX GALERA THERAPEUTICS INCSold out  $0-825,118-0.14%
ARYBU ARYA SCIENCES ACQUISIT...unit 06/09/2027Sold out  $0-700,000-0.14%
VSTM VERASTEM INCSold out  $0-8,066,171-0.18%
FSDC FS DEV CORPSold out  $0-1,000,000-0.20%
PRVL PREVAIL THERAPEUTICS INCSold out  $0-1,915,568-0.36%
RLMD RELMADA THERAPEUTICS INCSold out  $0-781,290-0.54%
RTRX RETROPHIN INCSold out  $0-4,635,687-1.57%
EIDX EIDOS THERAPEUTICS INCSold out  $0-2,163,271-2.00%
MCRB SERES THERAPEUTICS INCSold out  $0-4,750,000-2.46%