| Ticker | Name | Value | Shares | ↓ Weighting | ||||
|---|---|---|---|---|---|---|---|---|
| SGEN | Seagen Inc. | $8,278,767 | -10.5% | 47,269,424 | 0.0% | 31.19% | -15.6% | |
| BGNE | BeiGene, Ltd.sponsored adr | Reduce | $3,015,126 | -20.9% | 11,668,897 | -12.3% | 11.36% | -25.4% |
| INCY | Incyte Corporation | Add | $2,783,337 | -3.1% | 31,999,741 | 0.0% | 10.49% | -8.6% |
| ACAD | ACADIA Pharmaceuticals... | $2,240,219 | 29.6% | 41,904,586 | 0.0% | 8.44% | 22.2% | |
| KOD | Kodiak Sciences Inc. | Add | $2,039,104 | 178.8% | 13,879,952 | 12.4% | 7.68% | 162.9% |
| ALXN | Alexion Pharmaceutical... | $1,368,786 | 36.5% | 8,760,794 | 0.0% | 5.16% | 28.7% | |
| PRLD | Prelude Therapeutics I... | $723,988 | 137.5% | 10,118,636 | 0.0% | 2.73% | 123.9% | |
| BMRN | BioMarin Pharmaceutica... | $665,505 | 15.3% | 7,589,294 | 0.0% | 2.51% | 8.7% | |
| NVTA | Invitae Corporation | Add | $654,292 | 27.4% | 15,649,182 | 32.0% | 2.46% | 20.1% |
| ASND | Ascendis Pharma A/Ssponsored adr | $590,446 | 8.1% | 3,540,270 | 0.0% | 2.22% | 1.9% | |
| AbCellera Biologics Inc. | New | $420,515 | – | 10,450,180 | – | 1.58% | – | |
| MRTX | Mirati Therapeutics, Inc. | $309,645 | 32.3% | 1,409,784 | 0.0% | 1.17% | 24.7% | |
| ARGX | argenx SEsponsored adr | $299,842 | 12.0% | 1,019,557 | 0.0% | 1.13% | 5.6% | |
| IGMS | IGM Biosciences, Inc. | Add | $277,663 | 19.6% | 3,144,892 | 0.0% | 1.05% | 12.8% |
| MDGL | Madrigal Pharmaceutica... | $166,668 | -6.4% | 1,499,213 | 0.0% | 0.63% | -11.7% | |
| AMRN | Amarin Corporation plcsponsored adr | Reduce | $136,880 | 1.5% | 27,991,761 | -12.6% | 0.52% | -4.3% |
| HRTX | Heron Therapeutics, Inc. | $126,878 | 42.8% | 5,994,704 | 0.0% | 0.48% | 34.6% | |
| KYMR | Kymera Therapeutics, Inc. | $121,471 | 91.9% | 1,959,211 | 0.0% | 0.46% | 80.9% | |
| ALLK | Allakos Inc. | Add | $99,995 | 75.8% | 714,250 | 2.3% | 0.38% | 65.7% |
| CERS | Cerus Corporation | $94,895 | 10.5% | 13,713,195 | 0.0% | 0.36% | 4.2% | |
| BCRX | BioCryst Pharmaceutica... | $94,584 | 116.9% | 12,695,818 | 0.0% | 0.36% | 104.5% | |
| PACB | Pacific Biosciences of... | Reduce | $83,059 | 158.9% | 3,201,972 | -1.5% | 0.31% | 144.1% |
| ZYME | Zymeworks Inc. | $80,742 | 1.5% | 1,708,472 | 0.0% | 0.30% | -4.3% | |
| INSM | Insmed Incorporated | Reduce | $71,773 | -1.7% | 2,156,001 | -5.1% | 0.27% | -7.4% |
| FMTX | Forma Therapeutics Hol... | Add | $70,668 | -20.0% | 2,024,876 | 14.3% | 0.27% | -24.5% |
| RYTM | Rhythm Pharmaceuticals... | Reduce | $68,821 | 28.5% | 2,314,873 | -6.3% | 0.26% | 21.2% |
| NBIX | Neurocrine Biosciences... | $64,888 | -0.3% | 676,975 | 0.0% | 0.24% | -6.0% | |
| AXSM | Axsome Therapeutics, Inc. | Reduce | $63,452 | -7.2% | 778,834 | -18.9% | 0.24% | -12.5% |
| RARE | Ultragenyx Pharmaceuti... | New | $61,524 | – | 444,444 | – | 0.23% | – |
| NRIX | Nurix Therapeutics, Inc. | $58,820 | -5.8% | 1,788,921 | 0.0% | 0.22% | -11.2% | |
| BCEL | Atreca, Inc. | $57,054 | 15.6% | 3,532,760 | 0.0% | 0.21% | 9.0% | |
| NLTX | Neoleukin Therapeutics... | $53,887 | 17.5% | 3,821,740 | 0.0% | 0.20% | 10.8% | |
| ADAP | Adaptimmune Therapeuti...sponsored adr | Add | $52,988 | 4.9% | 9,830,877 | 55.3% | 0.20% | -1.1% |
| APLS | Apellis Pharmaceutical... | $51,283 | 89.6% | 896,551 | 0.0% | 0.19% | 78.8% | |
| KNSA | Kiniksa Pharmaceutical... | $49,469 | 15.3% | 2,799,577 | 0.0% | 0.19% | 8.7% | |
| ADCT | ADC Therapeutics SA | Reduce | $45,394 | -18.5% | 1,418,107 | -16.0% | 0.17% | -23.1% |
| ALGS | Aligos Therapeutics, Inc. | New | $44,517 | – | 1,610,000 | – | 0.17% | – |
| HZNP | Horizon Therapeutics P... | Reduce | $43,825 | -15.4% | 599,110 | -10.1% | 0.17% | -20.2% |
| KRYS | Krystal Biotech, Inc. | Reduce | $41,932 | 25.7% | 698,874 | -9.8% | 0.16% | 18.5% |
| CCXI | ChemoCentryx, Inc. | Reduce | $40,663 | -17.5% | 656,710 | -27.0% | 0.15% | -22.3% |
| GBT | Global Blood Therapeut... | $39,861 | -21.5% | 920,375 | 0.0% | 0.15% | -25.9% | |
| DBVT | DBV Technologies S.A.sponsored adr | $38,289 | 51.4% | 14,614,264 | 0.0% | 0.14% | 42.8% | |
| OPT | Opthea Limitedsponsored ads | New | $37,107 | – | 3,308,705 | – | 0.14% | – |
| MRUS | Merus N.V. | $35,717 | 46.1% | 2,037,469 | 0.0% | 0.13% | 37.7% | |
| ALKS | Alkermes plc | Add | $30,626 | 36.0% | 1,535,149 | 13.0% | 0.12% | 28.2% |
| FREQ | Frequency Therapeutics... | Reduce | $30,200 | 65.6% | 856,507 | -9.8% | 0.11% | 56.1% |
| PTGX | Protagonist Therapeuti... | Reduce | $28,954 | -7.2% | 1,436,192 | -10.0% | 0.11% | -12.5% |
| BioAtla, Inc. | New | $28,058 | – | 825,000 | – | 0.11% | – | |
| RETA | Reata Pharmaceuticals,...cl a | Add | $27,688 | 434.4% | 223,976 | 321.1% | 0.10% | 403.9% |
| ATHA | Athira Pharma, Inc. | Reduce | $27,618 | 69.6% | 806,367 | -8.6% | 0.10% | 59.9% |
| AGLE | Aeglea BioTherapeutics... | Reduce | $26,838 | -13.6% | 3,410,106 | -22.1% | 0.10% | -18.5% |
| FLGT | Fulgent Genetics, Inc. | Reduce | $25,819 | 18.1% | 495,573 | -9.3% | 0.10% | 11.3% |
| ADPT | Adaptive Biotechnologi... | Reduce | $22,451 | 4.8% | 379,682 | -13.8% | 0.08% | -1.2% |
| VSTM | Verastem, Inc. | New | $21,607 | – | 10,144,039 | – | 0.08% | – |
| MREO | Mereo BioPharma Group plcads | New | $21,588 | – | 6,030,293 | – | 0.08% | – |
| ALT | Altimmune, Inc. | Reduce | $21,257 | -27.0% | 1,884,451 | -14.6% | 0.08% | -31.2% |
| AUPH | Aurinia Pharmaceutical... | Reduce | $19,501 | -18.2% | 1,410,064 | -12.9% | 0.07% | -22.9% |
| IMTX | Immatics N.V. | Add | $19,476 | 83.3% | 1,805,025 | 80.2% | 0.07% | 72.8% |
| NVAX | Novavax, Inc. | Reduce | $18,924 | -6.8% | 169,706 | -9.4% | 0.07% | -12.1% |
| IDRA | Idera Pharmaceuticals,... | $16,914 | 71.5% | 4,608,786 | 0.0% | 0.06% | 61.7% | |
| CBAY | Cymabay Therapeutics, ... | Reduce | $16,607 | -29.5% | 2,893,276 | -11.0% | 0.06% | -33.5% |
| Invitae Corporationnote 2.0% 9/1/2024 | $16,446 | -2.7% | 10,300,000 | 0.0% | 0.06% | -8.3% | ||
| XNCR | Xencor, Inc. | Reduce | $16,116 | 1.3% | 369,370 | -9.9% | 0.06% | -4.5% |
| BioMarin Pharmaceutica...note 0.599% 8/1/2024 | $16,033 | 2.4% | 15,000,000 | 0.0% | 0.06% | -3.4% | ||
| ALBO | Albireo Pharma, Inc. | Reduce | $15,472 | -15.6% | 412,466 | -24.9% | 0.06% | -20.4% |
| SGMO | Sangamo Therapeutics, ... | Reduce | $13,379 | 49.1% | 857,339 | -9.7% | 0.05% | 40.5% |
| GWPH | GW Pharmaceuticals plcads | Reduce | $13,029 | -3.5% | 112,897 | -18.6% | 0.05% | -9.1% |
| GMDA | Gamida Cell Ltd. | Add | $12,990 | 394.3% | 1,548,314 | 144.5% | 0.05% | 366.0% |
| KDNY | Chinook Therapeutics, ... | New | $11,874 | – | 748,693 | – | 0.04% | – |
| FPRX | Five Prime Therapeutic... | New | $11,363 | – | 668,000 | – | 0.04% | – |
| MIRM | Mirum Pharmaceuticals,... | Add | $11,302 | 6.1% | 647,313 | 17.1% | 0.04% | -0.0% |
| Silverback Therapeutic... | New | $11,033 | – | 238,095 | – | 0.04% | – | |
| XENE | Xenon Pharmaceuticals ... | Reduce | $10,572 | 25.6% | 687,386 | -9.6% | 0.04% | 18.4% |
| BLUE | bluebird bio, Inc. | Reduce | $9,822 | -27.8% | 226,988 | -9.9% | 0.04% | -31.9% |
| ISEE | IVERIC bio, Inc. | $9,716 | 22.5% | 1,406,037 | 0.0% | 0.04% | 15.5% | |
| ASMB | Assembly Biosciences, ... | $9,326 | -63.2% | 1,541,418 | 0.0% | 0.04% | -65.3% | |
| ANAB | AnaptysBio, Inc. | Reduce | $9,184 | 27.8% | 427,179 | -12.3% | 0.03% | 20.5% |
| CRNX | Crinetics Pharmaceutic... | Add | $8,699 | 83.6% | 616,520 | 103.9% | 0.03% | 73.1% |
| VXRT | Vaxart, Inc. | Reduce | $7,987 | -23.3% | 1,398,795 | -10.7% | 0.03% | -27.7% |
| CABA | Cabaletta Bio, Inc. | $7,942 | 15.1% | 636,363 | 0.0% | 0.03% | 8.6% | |
| HOOK | HOOKIPA Pharma Inc. | $7,768 | 17.1% | 700,481 | 0.0% | 0.03% | 10.4% | |
| SYRS | Syros Pharmaceuticals,... | $7,488 | 22.7% | 690,167 | 0.0% | 0.03% | 15.7% | |
| DNLI | Denali Therapeutics Inc. | Reduce | $7,433 | 108.7% | 88,738 | -10.7% | 0.03% | 96.7% |
| KRTX | Karuna Therapeutics, Inc. | Reduce | $7,108 | 18.2% | 69,966 | -10.0% | 0.03% | 11.4% |
| AUTL | Autolus Therapeutics plcsponsored ads | Add | $6,993 | 30.2% | 782,183 | 69.6% | 0.03% | 22.8% |
| HRMY | Harmony Biosciences Ho... | Reduce | $6,507 | -52.0% | 180,000 | -55.0% | 0.02% | -54.8% |
| GTH | Genetron Holdings Limitedads | Add | $6,374 | 433.8% | 455,306 | 355.3% | 0.02% | 403.3% |
| NTLA | Intellia Therapeutics,... | Reduce | $6,055 | 149.2% | 111,296 | -9.0% | 0.02% | 134.9% |
| PASG | Passage Bio, Inc. | Reduce | $6,018 | 75.8% | 235,362 | -9.8% | 0.02% | 65.8% |
| REPL | Replimune Group, Inc. | Reduce | $5,856 | 23.1% | 153,512 | -25.7% | 0.02% | 16.1% |
| ITOS | Iteos Therapeutics, Inc. | Reduce | $5,085 | 23.0% | 150,346 | -10.3% | 0.02% | 16.0% |
| TARA | Protara Therapeutics, ... | $4,834 | 43.9% | 199,671 | 0.0% | 0.02% | 35.6% | |
| BNR | Burning Rock Biotech L...sponsored ads | Reduce | $4,831 | -18.8% | 209,131 | -11.9% | 0.02% | -23.5% |
| GOSS | Gossamer Bio, Inc. | New | $4,649 | – | 480,729 | – | 0.02% | – |
| MGNX | MacroGenics, Inc. | New | $4,588 | – | 200,679 | – | 0.02% | – |
| TCDA | Tricida, Inc. | New | $4,437 | – | 629,300 | – | 0.02% | – |
| IFRX | Inflarx N.V. | Reduce | $4,307 | 0.3% | 856,228 | -15.0% | 0.02% | -5.4% |
| ALEC | Alector, Inc. | Reduce | $3,620 | 29.4% | 239,228 | -9.9% | 0.01% | 22.0% |
| LOGC | LogicBio Therapeutics,... | New | $3,445 | – | 451,478 | – | 0.01% | – |
| TCRR | TCR2 Therapeutics Inc. | Reduce | $3,430 | 37.8% | 110,888 | -9.5% | 0.01% | 29.9% |
| CNST | Constellation Pharmace... | Reduce | $3,304 | 22.3% | 114,735 | -13.9% | 0.01% | 15.3% |
| LEGN | Legend Biotech Corpora...sponsored ads | Reduce | $3,256 | -17.7% | 115,626 | -9.8% | 0.01% | -22.4% |
| NGM | NGM Biopharmaceuticals... | Reduce | $3,230 | 71.9% | 106,616 | -9.7% | 0.01% | 62.1% |
| CHMA | Chiasma, Inc. | $3,228 | 1.2% | 742,133 | 0.0% | 0.01% | -4.6% | |
| AKRO | Akero Therapeutics, Inc. | Reduce | $3,054 | -24.7% | 118,378 | -10.2% | 0.01% | -29.0% |
| XLRN | Acceleron Pharma Inc. | Reduce | $2,870 | -0.5% | 22,430 | -12.5% | 0.01% | -6.2% |
| DRNA | Dicerna Pharmaceutical... | Reduce | $2,250 | 10.6% | 102,121 | -9.7% | 0.01% | 4.2% |
| INZY | Inozyme Pharma, Inc. | Reduce | $2,208 | -29.1% | 106,999 | -9.7% | 0.01% | -33.2% |
| OVID | Ovid Therapeutics Inc. | Add | $2,208 | -34.9% | 955,690 | 61.8% | 0.01% | -38.6% |
| VKTX | Viking Therapeutics, Inc. | Reduce | $2,049 | -12.9% | 363,980 | -10.0% | 0.01% | -17.9% |
| RCUS | Arcus Biosciences, Inc. | Reduce | $1,888 | -4.6% | 72,709 | -37.0% | 0.01% | -10.0% |
| ORTX | Orchard Therapeutics plcads | Reduce | $1,436 | 1.8% | 332,502 | -3.1% | 0.01% | -4.0% |
| LPTX | Leap Therapeutics, Inc. | $1,259 | 13.6% | 559,705 | 0.0% | 0.00% | 7.1% | |
| MTEM | Molecular Templates, Inc. | Reduce | $1,257 | -22.6% | 133,833 | -10.1% | 0.00% | -27.1% |
| OYST | Oyster Point Pharma, Inc. | Reduce | $1,156 | -19.7% | 61,424 | -10.0% | 0.00% | -24.3% |
| GLPG | Galapagos NVsponsored adr | Reduce | $1,107 | -37.1% | 11,180 | -9.9% | 0.00% | -40.7% |
| INFI | Infinity Pharmaceutica... | Reduce | $1,107 | 63.0% | 522,360 | -10.0% | 0.00% | 53.7% |
| EVFM | Evofem Biosciences, Inc. | Reduce | $991 | -3.0% | 411,396 | -5.0% | 0.00% | -8.6% |
| Affimed N.V. | Reduce | $958 | 49.0% | 164,605 | -13.3% | 0.00% | 40.5% | |
| Bellicum Pharmaceutica... | $879 | -46.3% | 249,123 | 0.0% | 0.00% | -49.4% | ||
| KZR | Kezar Life Sciences, Inc. | Reduce | $729 | -73.8% | 139,676 | -75.7% | 0.00% | -75.3% |
| ADMS | Adamas Pharmaceuticals... | Reduce | $641 | -5.0% | 147,996 | -9.7% | 0.00% | -10.5% |
| GLMD | Galmed Pharmaceuticals... | Reduce | $575 | -20.7% | 184,927 | -10.0% | 0.00% | -25.2% |
| QURE | uniQure N.V. | Reduce | $244 | -96.6% | 6,740 | -96.5% | 0.00% | -96.8% |
| SNSS | Sunesis Pharmaceutical... | New | $106 | – | 53,066 | – | 0.00% | – |
| GNFT | Genfit SAads | Reduce | $71 | -52.7% | 14,720 | -48.2% | 0.00% | -55.4% |
| SNSS | Sunesis Pharmaceutical... | Sold out | $0 | – | -53,066 | – | -0.00% | – |
| ARAV | Aravive, Inc. | Sold out | $0 | – | -75,854 | – | -0.00% | – |
| APLT | Applied Therapeutics, ... | Sold out | $0 | – | -38,034 | – | -0.00% | – |
| CPRX | Catalyst Pharmaceutica... | Sold out | $0 | – | -474,400 | – | -0.01% | – |
| UROV | Urovant Sciences Ltd. | Sold out | $0 | – | -978,505 | – | -0.04% | – |
| IMMU | Immunomedics, Inc. | Sold out | $0 | – | -237,694 | – | -0.08% | – |
| Neurocrine Biosciences...note 2.25% 5/15/2024 | Sold out | $0 | – | -30,770,000 | – | -0.17% | – | |
| EXAS | Exact Sciences Corpora... | Sold out | $0 | – | -1,846,139 | – | -0.75% | – |
| MYOK | MyoKardia, Inc. | Sold out | $0 | – | -3,009,344 | – | -1.64% | – |
Download | ||||||||
- Portfolio
- Total value$26.5 Billion
- Holdings126
- Turnover20.0%
- Managers
- Strategy
- Healthcare
- Filings
- EDGAR
February 16, 2021 15:59